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005 20141212020756.0;

008 060125s2005 nyua b 001 0 eng ;

020 a| 1402037635;

020 a| 9781402037634;

035 a| (Sirsi) H1037786;

035 a| (OCoLC)63394908;

049 a| NEHH;

245 00 a| Genome instability in cancer development /c| edited by Erich A. Nigg.;

300 a| xv, 511 pages :b| illustrations (some color) ;c| 26 cm.;

336 a| text2| rdacontent;

337 a| unmediated2| rdamedia;

338 a| volume2| rdacarrier;

490 1 a| Advances in experimental medicine and biology ;v| v. 570;

504 a| Includes bibliographical references and index.;

505 0 a| The problem of genome instability. The multiplicity of mutations in human cancers / Ranga N. Venkatesan and Lawrence A. Loeb. Monitoring chromosome rearrangements / Michael R. Speicher -- DNA repair and mutagenesis. Nucleotide excision repair and its connection with cancer and ageing / Jaan-Olle Andressoo, Jan H.J. Hoeijmakers and Harm de Waard. DNA mismatch repair and colon cancer / Giancarlo Marra and Josef Jiricny. Base excision repair / Lisiane B. Meira, Nicholas E. Burgis and Leona D. Samson. Genomic instability in cancer development / Penny A. Jeggo. Translesion synthesis and error-prone polymerases / Catherine M. Green and Alan R. Lehmann -- Cell cycle progression and chromosome aberration. The INK4A/ARF network-cell cycle checkpoint or emergency brake? / Ana Gutierrez del Arroyo and Gordon Peters. DNA replication and genomic instability / Wenge Zhu, Tarek Abbas and Anindya Dutta. The dream of every chromosome: equal segregation for a healthy life of the host / Tomohiro Matsumoto and Mitsuhiro Yanagida. Telomere structural dynamics in genome integrity control and carcinogenesis / Roger A. Greenberg and K. Lenhard Rudolph. Gene amplification mechanisms / Michelle Debatisse and Bernard Malfoy. DNA methylation and cancer-associated genetic instability / Melanie Ehrlich. Deregulation of the centrosome cycle and the origin of chromosomal instability in cancer / Wilma L. Lingle, Kara Lukaswiewicz and Jeffrey L. Salisbury -- Genome integrity checkpoints. Mammalian DNA damage response pathway / Zhenkun Lou and Junjie Chen. ATM and cellular response to DNA damage / Martin F. Lavin ... [et al.] Mitotic checkpoint, aneuploidy and cancer / Tim J. Yen and Gary D. Kao.;

650 12 a| Neoplasmsx| genetics.=| ^A920613;

650 12 a| Neoplasmsx| etiology.=| ^A917753;

650 22 a| Genomic Instability.=| ^A941562;

650 22 a| Mutation.=| ^A917789;

650 22 a| DNA Repair.=| ^A923057;

700 1 a| Nigg, Erich A.=| ^A869740;

830 0 a| Advances in experimental medicine and biologyv| v. 570.=| ^A103;

994 a| C0b| NEH;

919 a| BOOK;

959 a| 1037786;

096 a| QZ 202 G335 2005;

596 a| 4;

998 a| 1572342;

999 a| QZ 202 G335 2005w| NLMc| 1i| 31740007962263d| 2/2/2011e| 1/7/2009f| 2/2/2011g| 1l| HSLBKm| HSLn| 2p| $159.00r| Ys| Yt| HBKu| 4/11/2006x| BOOKz| HSTACKSo| .STAFF. 0;

Genome instability in cancer development / edited by Erich A. Nigg.

Other author	Nigg, Erich A.
Format	Book
Publication Info	New York : Springer, ©2005.
Description	xv, 511 pages : illustrations (some color) ; 26 cm.
Subjects	Neoplasms--genetics. Neoplasms--etiology. Genomic Instability. Mutation. DNA Repair.

Series	Advances in experimental medicine and biology ; v. 570 Advances in experimental medicine and biology v. 570. ^A103
Contents	The problem of genome instability. The multiplicity of mutations in human cancers / Ranga N. Venkatesan and Lawrence A. Loeb. Monitoring chromosome rearrangements / Michael R. Speicher -- DNA repair and mutagenesis. Nucleotide excision repair and its connection with cancer and ageing / Jaan-Olle Andressoo, Jan H.J. Hoeijmakers and Harm de Waard. DNA mismatch repair and colon cancer / Giancarlo Marra and Josef Jiricny. Base excision repair / Lisiane B. Meira, Nicholas E. Burgis and Leona D. Samson. Genomic instability in cancer development / Penny A. Jeggo. Translesion synthesis and error-prone polymerases / Catherine M. Green and Alan R. Lehmann -- Cell cycle progression and chromosome aberration. The INK4A/ARF network-cell cycle checkpoint or emergency brake? / Ana Gutierrez del Arroyo and Gordon Peters. DNA replication and genomic instability / Wenge Zhu, Tarek Abbas and Anindya Dutta. The dream of every chromosome: equal segregation for a healthy life of the host / Tomohiro Matsumoto and Mitsuhiro Yanagida. Telomere structural dynamics in genome integrity control and carcinogenesis / Roger A. Greenberg and K. Lenhard Rudolph. Gene amplification mechanisms / Michelle Debatisse and Bernard Malfoy. DNA methylation and cancer-associated genetic instability / Melanie Ehrlich. Deregulation of the centrosome cycle and the origin of chromosomal instability in cancer / Wilma L. Lingle, Kara Lukaswiewicz and Jeffrey L. Salisbury -- Genome integrity checkpoints. Mammalian DNA damage response pathway / Zhenkun Lou and Junjie Chen. ATM and cellular response to DNA damage / Martin F. Lavin ... [et al.] Mitotic checkpoint, aneuploidy and cancer / Tim J. Yen and Gary D. Kao.
Bibliography note	Includes bibliographical references and index.
ISBN	1402037635
ISBN	9781402037634

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Laupus	Books - Stacks	QZ 202 G335 2005	✔ Available	Place Hold

Genome instability in cancer development / edited by Erich A. Nigg.

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