Pharmacogenetics of breast cancer : towards the individualization of therapy / edited by Brian Leyland-Jones.

Other author Leyland-Jones, Brian.
Format Book
Publication InfoNew York : Informa Healthcare, ©2008.
Descriptionxiv, 334 pages : illustrations ; 24 cm.
Subjects

SeriesTranslational medicine series ; 7
Translational medicine series ; 7. ^A1249116
Contents Pharmacogenetics of breast cancer: towards the individualization of therapy / Jenny C. Chang ... [et al.] -- Pharmacology, pharmacogenetics, and pharmacoepidemiology: three P's of individualized therapy / Shaheenah Dawood -- Role of genetic variability in breast cancer treatment outcomes / Kandace L. Amend, Ji-Yeob Choi, and Christine B. Ambrosone -- The role of epigenetics in breast cancer: implications for diagnosis, prognosis, and treatments / Amy M. Dworkin, Tim H.-M. Huang, and Amanda E. Toland -- Comparative genomic hybridization and copy number abnormalities in breast cancer / Nicholas Wang and Joe Gray -- Gene expression profiling as an emerging diagnostic tool to personalize chemotherapy selection for early stage breast cancer / Cornelia Liedtke and Lajos Pusztai -- Gene expression-based predictors of prognosis and response to chemotherapy in breast cancer / Soonmyung Paik -- Utilization of genomic signatures for personalized treatment of breast cancer / P. Kelly Marcom ... [et al.] -- Personalized medicine by the use of microarray gene expression profiling / S. Mook, F. Cardoso, Laura J. van 't Veer, and Fatima Cardoso -- Predictive markers for targeted breast cancer treatment / Hans Christian B. Pedersen and John M.S. Bartlett -- Circulating tumor cells in individualizing breast cancer therapy / James M. Reuben and Massimo Cristofanilli -- Individualization of endocrine therapy in breast cancer / Amelia Zelnak, Ruth M. O'Regan , and Clodia Osipo --
Contents TAILORx : rationale for the study design / Joseph A. Sparano -- Taking prognostic signatures to the clinic / Michail Ignatiadis and Christos Sotiriou -- Tissue is the issue / Adekunle Raji -- Acquisition and preservation of tissue for microarray analysis / Brian R. Untch and John A. Olson -- Tapping into the formalin-fixed paraffin-embedded (FFPE) tissue goldmine for individualization of breast cancer treatment / Mark Abramovitz and Brian Leyland-Jones -- Breast cancer stem cells and their niche: lethal seeds in lethal soil / Danuta Balicki, Brian Leyland-Jones, and Max S. Wicha -- Molecular imaging in individualized cancer management / David M. Schuster and Diego R. Martin -- Cancer nanotechnology for molecular profiling and individualized therapy / May Dongmei Wang, Jonathan W. Simons, and Shuming Nie.
Bibliography noteIncludes bibliographical references and index.
LCCN 2008001013
ISBN9781420052930 :
ISBN1420052934