The maturity onset relationship of prostaglandin F₂cc in rabbit serum / by Floyd Ernest Bell, Jr.
| Author/creator | Bell, Floyd E. author. |
| Other author | Smith, W. James, degree supervisor. |
| Other author | East Carolina University. Department of Biology. |
| Format | Theses and dissertations |
| Production | 1976. |
| Description | 54 leaves : illustrations ; 28 cm |
| Supplemental Content | Access via ScholarShip |
| Subjects |
| Summary | The purpose of this study was to determine if there exists a direct relationship between peripheral serum prostaglandin concentration and age. Past research has indicated a strong connection between prostaglandins and the reproductive process. The biologically active group of fatty acids has been the subject of many studies during the last 40 years, but until this time, there has been no study of the relationship of prostaglandin level to sexual maturity. Using past research as a basis for investigation, experiments were arranged to investigate the possibility of a connection between puberty and a rise in serum prostaglandin level. The New Zealand White rabbit (Oryctolagus cuniculus) was the experimental animal and radioimmunoassay was the procedure for the determination of prostaglandin level. The rabbits were tested at ages varying from 1 day to 2 years and the prostaglandin level of the animals was compared to known solutions of prostaglandin. This method was used to determine the prostaglandin concentration in nanograms per milliliter of blood serum from animals of different ages. These results were correlated to determine if there was a direct relationship between Increasing age and blood serum prostaglandin level. The data Indicated that there was no direct relationship between sexual maturity and serum prostaglandin level, but that other factors probably control the blood prostaglandin level. |
| Local note | Joyner-"Presented to the faculty of the Department of Biology ... in partial fulfillment of the requirements for the degree Master of Science in Biology." |
| General note | Presented to the faculty of the Department of Biology |
| General note | Advisor: William James Smith |
| Dissertation note | M.S. East Carolina University |
| Bibliography note | Includes bibliographical references (leaves 52-54). |
| Genre/form | Academic theses. |
| Genre/form | Academic theses. |
| Genre/form | Thèses et écrits académiques. |