The effects of exercise on protein degradation / by Richard T. Williams.
| Author/creator | Williams, Richard T. author. |
| Other author | Dohm, G. Lynis, degree supervisor. |
| Other author | East Carolina University. Department of Biology. |
| Format | Theses and dissertations |
| Production | 1981. |
| Description | 50 leaves : illustrations ; 28 cm |
| Supplemental Content | Access via ScholarShip |
| Subjects |
| Summary | This study was undertaken to further clarify the effects of exhaustive exercise on protein degradation. Measurement of urea and NT- methylhistidine, in both rats and humans, was utilized as an indicator of protein catabolism. In rats, an exhaustive exercise bout resulted in increased urinary levels of urea and NT-methylhistidine. Plasma NT- methylhistidine was also significantly elevated in rats after an exercise bout. Human studies too revealed increased excretion of urea (both urinary and sweat) and NT-methylhistidine accompanied by increases in plasma levels of NT-methylhistldine. The results from this study have demonstrated an increased protein utilization as the result of intense exercise. The large increase in NT- methylhistidine seen in the post-exercise samples Indicates that muscle catabolism is initiated by stressful exercise. The increase in urea from both sweat and urine is probably potentiated through two mechanisms: (1) the direct utilization of the carbon skeletons resulting from catabolism in the TCA cycle and (2) to restore lowered glucose levels in the body via gluconeogenesis. |
| General note | "Presented to the faculty of the Department of Biology ... in partial fulfillment of the requirements for the degree Master of Science in Biology." |
| General note | Advisor: G. Lynis Dohm |
| Dissertation note | M.S. East Carolina University 1981 |
| Bibliography note | Includes bibliographical references (leaves 45-50). |
| Genre/form | dissertations. |
| Genre/form | Academic theses. |
| Genre/form | Academic theses. |
| Genre/form | Thèses et écrits académiques. |