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LEADER 03971cam 2200493 a 4500

001 ocn658536812;

003 OCoLC;

005 20141212054643.0;

008 100823s2011 flua b 001 0 eng ;

010 a| 2010034913;

016 7 a| 1015388392| DNLM;

019 a| 607983128;

020 a| 9781439809648 (hardcover : alk. paper);

020 a| 143980964X (hardcover : alk. paper);

029 1 a| NLMb| 101538839;

029 1 a| AU@b| 000045986900;

035 a| (Sirsi) o658536812;

035 a| (OCoLC)658536812;

042 a| pcc;

049 a| EREE;

050 00 a| QP552.M46b| P765 2011;

082 00 a| 572/.6332| 22;

245 00 a| Protein folding and metal ions :b| mechanisms, biology and disease /c| edited by Cláudio M. Gomes, Pernilla Wittung-Stafshede.;

300 a| xiv, 294 pages :b| illustrations ;c| 25 cm;

336 a| text2| rdacontent;

337 a| unmediated2| rdamedia;

338 a| volume2| rdacarrier;

504 a| Includes bibliographical references and index.;

505 8 a| (Publisher-supplied data) Chapter 1. Metal Ions, Protein Folding, and Conformational States: An Introduction 3 Cláudio M. Gomes and Pernilla Wittung-Stafshede Chapter 2. The Folding Mechanism of c-Type Cytochromes 13 Carlo Travaglini-Allocatelli, Stefano Gianni, and Maurizio Brunori Chapter 3. The Mechanism of Cytochrome C Folding: Early Events and Kinetic Intermediates 37 Eefei Chen, Robert A. Goldbeck, and David S. Kliger Chapter 4. Stability and Folding of Copper-Binding Proteins 61 Irina Pozdnyakova and Pernilla Wittung-Stafshede Chapter 5. Iron-Sulfur Clusters, Protein Folds, and Ferredoxin Stability 81 Sónia S. Leal and Cláudio M. Gomes Chapter 6. Folding and Stability of Myoglobins and Hemoglobins 97 David S. Culbertson and John S. Olson Chapter 7. Frataxin: An Unusual Metal-Binding Protein in Search of a Function 125 Annalisa Pastore Chapter 8. Mechanism of Human Copper Transporter Wilson's Disease Protein 145 Amanda Barry, Zara Akram, and Svetlana Lutsenko Chapter 9. a-Synuclein and Metals 169 Aaron Santner and Vladimir N. Uversky Chapter 10. Zinc and p53 Misfolding 193 James S. Butler and Stewart N. Loh Chapter 11. The Octarepeat Domain of the Prion Protein and Its Role in Metal Ion Coordination and Disease 209 Glenn L. Millhauser Chapter 12. Metallopeptides as Tools to Understand Metalloprotein Folding and Stability 227 Brian R. Gibney Chapter 13. The Folding Landscapes of Metalloproteins 247 Patrick Weinkam and Peter G. Wolynes.;

520 a| "Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher.;

650 0 a| Metalloproteins.=| ^A13122;

650 0 a| Protein folding.=| ^A312811;

700 1 a| Gomes, Cláudio M.,d| 1970-=| ^A1034977;

700 1 a| Wittung-Stafshede, Pernilla,d| 1968-=| ^A1034978;

949 a| QP552.M46b| P765 2011h| JOYNER48o| jmpli| 30372014892589;

994 a| C0b| ERE;

938 a| Baker and Taylorb| BTCPn| BK0008920797;

938 a| Coutts Information Servicesb| COUTn| 12905963;

938 a| YBP Library Servicesb| YANKn| 3476346;

596 a| 1;

998 a| 2389851;

999 a| QP552.M46 P765 2011w| LCc| 1i| 30372014892589d| 4/27/2022e| 7/7/2021l| JGESm| JOYNERn| 3r| Ys| Yt| JGESBKu| 2/14/2011x| BOOKz| JSTACKSo| .STAFF. jmpl;

Protein folding and metal ions : mechanisms, biology and disease / edited by Cláudio M. Gomes, Pernilla Wittung-Stafshede.

Other author	Gomes, Cláudio M., 1970-
Other author	Wittung-Stafshede, Pernilla, 1968-
Format	Book
Publication Info	Boca Raton, FL : CRC Press, ©2011.
Description	xiv, 294 pages : illustrations ; 25 cm
Subjects	Metalloproteins. Protein folding.

Contents	(Publisher-supplied data) Chapter 1. Metal Ions, Protein Folding, and Conformational States: An Introduction 3 Cláudio M. Gomes and Pernilla Wittung-Stafshede Chapter 2. The Folding Mechanism of c-Type Cytochromes 13 Carlo Travaglini-Allocatelli, Stefano Gianni, and Maurizio Brunori Chapter 3. The Mechanism of Cytochrome C Folding: Early Events and Kinetic Intermediates 37 Eefei Chen, Robert A. Goldbeck, and David S. Kliger Chapter 4. Stability and Folding of Copper-Binding Proteins 61 Irina Pozdnyakova and Pernilla Wittung-Stafshede Chapter 5. Iron-Sulfur Clusters, Protein Folds, and Ferredoxin Stability 81 Sónia S. Leal and Cláudio M. Gomes Chapter 6. Folding and Stability of Myoglobins and Hemoglobins 97 David S. Culbertson and John S. Olson Chapter 7. Frataxin: An Unusual Metal-Binding Protein in Search of a Function 125 Annalisa Pastore Chapter 8. Mechanism of Human Copper Transporter Wilson's Disease Protein 145 Amanda Barry, Zara Akram, and Svetlana Lutsenko Chapter 9. a-Synuclein and Metals 169 Aaron Santner and Vladimir N. Uversky Chapter 10. Zinc and p53 Misfolding 193 James S. Butler and Stewart N. Loh Chapter 11. The Octarepeat Domain of the Prion Protein and Its Role in Metal Ion Coordination and Disease 209 Glenn L. Millhauser Chapter 12. Metallopeptides as Tools to Understand Metalloprotein Folding and Stability 227 Brian R. Gibney Chapter 13. The Folding Landscapes of Metalloproteins 247 Patrick Weinkam and Peter G. Wolynes.
Abstract	"Interest in the uses and applications of metallo-chemistry in the life sciences continues to expand. This book provides a broad overview of metals and protein folding. It addresses fundamental aspects of the folding, stability, and design of metal binding proteins and peptides along with biological aspects related to the action of metallochaperones. The text features practical information related to methodologies, particular techniques, and bibliographic references. Readers will gain the molecular basis for protein-metal interactions and a good perspective on the applications of protein coordination chemistry in life sciences and biotechnology"--Provided by publisher.
Bibliography note	Includes bibliographical references and index.
LCCN	2010034913
ISBN	9781439809648 (hardcover : alk. paper)
ISBN	143980964X (hardcover : alk. paper)

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Protein folding and metal ions : mechanisms, biology and disease / edited by Cláudio M. Gomes, Pernilla Wittung-Stafshede.

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