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RNA : life's indispensable molecule / James Darnell.
| Author/creator | Darnell, James E. |
| Format | Book |
| Publication Info | Cold Spring Harbor, N.Y. : Cold Spring Harbor Laboratory Press, ©2011. |
| Description | xiv, 416 pages : illustrations (some color) ; 24 cm |
| Subjects |
| Contents | The dawn of molecular biology : history of macromolecules before RNA -- RNA connects genes and proteins : ribosomes, tRNA, and messenger RNA -- After mRNA : the genetic code, translation, and the biochemistry of controlled RNA synthesis in bacteria -- Gene expression in mammalian cells : discovery of RNA processing, genes in pieces, and new RNA chemistry -- Controlling mRNA : the cell's most complicated task -- RNA and the beginning of life. |
| Abstract | In this textbook the author provides an account of RNA research, illuminated by his own life-long engagement in the field. He describes how scientists unraveled fundamental questions about the biochemical and genetic importance of RNA, how mRNAs are generated and used to produce proteins, how noncoding and catalytic RNAs mediate key cellular processes, and how RNA molecules likely initiated life on Earth. With a scope extending from the early 20th century to the present day, he conveys the intellectual context in which these questions first arose and explains how the key experiments were structured and answers obtained. The book is geared towards scientists from the graduate level on up. |
| Bibliography note | Includes bibliographical references (p. 397-398) and index. |
| LCCN | 2011001258 |
| ISBN | 9781936113194 (hard cover : alk. paper) |
| ISBN | 1936113198 (hard cover : alk. paper) |
| Standard identifier# | 40019764290 |