The toxicant induction of irritant asthma, rhinitis, and related conditions / William J. Meggs, editor.
| Other author | Meggs, William Joel, editor. |
| Format | Book |
| Publication | New York : Springer, [2013] |
| Description | vi, 294 pages : illustrations (some color) ; 24 cm |
| Subjects |
| Contents | Introduction: Irritant Asthma, Irritant Rhinitis, and Related Conditions / William J. Meggs -- Airway Anatomy, Physiology, and Inflammation / Michael R. Van Scott, Joyce Chandler, Stephen Olmstead, Jared M. Brown, Mark Mannie -- Reactive Airways Dysfunction Syndrome (RADS) and Irritant-Induced Asthma / Stuart M. Brooks -- Acute Toxicity of Respiratory Irritant Exposures / Susan Ney Miller -- Particulate Exposure and Cardiovascular Inflammation / Christopher J. Wingard, Emily Cozzi, Michael R. Van Scott, Robert M. Lust -- Products of Tobacco Combustion / Rebecca Bascom, Anne E.F. Dimmock, Judie Ann Howrylak -- Irritant and Airborne Contact Dermatitis / Payton A. Kuhlenbeck, Tanner J. Parrent -- Exposure Limits / Grace Ziem -- Occupational Issues Related to Respiratory Irritants / Ricky Langley, David Lipton -- The Brain as a Target Organ for Allergic and Irritant Sensitivity: A Review and Suggestions for Research / William J. Meggs, Richard M. Bloch, Kori Brewer. -- An Approach to Treating Irritant Airway Inflammation / Grace Ziem -- Summary and Research Needs / William J. Meggs. |
| Abstract | "Untoward reactions to environmental chemicals, particularly when a subject reports difficulties with exposures to chemicals of diverse classes involving more than one organ system, have been poorly understood and an area of great controversy. Studies of airway inflammation induced by respiratory irritants have established neurogenic inflammation as the mechanism for irritant asthma and rhinitis. Remodeling of the airway after an acute irritant exposure can lead to a heightened sensitivity to irritants that persists. Recognition that rhinitis, while sometimes regarded as a trivial disease, is associated with extra-airway manifestations such as fatigue and disturbances of sleep, mood, and cognition, further elucidates how chemical exposures can be serious for susceptible individuals. This book reviews current scientific understanding of irritant airway inflammation and related conditions, including cardiovascular effects of particulate exposures, airborne contact dermatitis and irritant dermatitis, and the brain as a target organ for both allergic and irritant reactions. It is essential reading for physicians and other healthcare workers caring for patients with environmental intolerances. Allergists, toxicologists, occupational and environmental physicians, and pulmonologists will find the materials particularly valuable. Patients and advocates for those with chemical intolerances will also find the book of interest."--Page 4 of cover. |
| Local note | Laupus-ECU authors |
| Local note | The chapter titled "Particulate exposures and cardiovascular inflammation" (pp. 103-130) was written by ECU faculty member, Robert Lust, PhD |
| Bibliography note | Includes bibliographical references and index. |
| LCCN | 2013953882 |
| ISBN | 9781461490432 (alk. paper) |
| ISBN | 146149043X (alk. paper) |
| ISBN | (eBook) |
| ISBN | 1461490448 |
| ISBN | 9781461490449 |
| Standard identifier# | 10.1007/978-1-4614-9044-9 |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Joyner | General Stacks | RC591 .T69 2013 | ✔ Available | Place Hold |
| Laupus | Books - Stacks | WF 553 M497 2013 | ✔ Available | Place Hold |