Biopharmaceutics modeling and simulations theory, practice, methods, and applications / Kiyohiko Sugano.

Author/creator Sugano, Kiyohiko
Format Electronic
Publication InfoHoboken, N.J. : John Wiley & Sons,
Description1 online resource.
Supplemental ContentFull text available from Ebook Central - Academic Complete
Subjects
Biopharmaceutics--methods.
Computer Simulation.
Drug Compounding--methods.
Models, Theoretical.

Contents Introduction -- Theoretical framework I : solubility -- Theoretical framework II : dissolution -- Theoretical framework III : biological membrane permeation -- Theoretical framework IV : gastrointestinal transit models and integration -- Physiology of gastrointestinal tract and other administration sites in humans and animals -- Drug parameters -- Validation of mechanistic models -- Bioequivalence and biopharmaceutical classification system -- Dose and particle size dependency -- Enabling formulations -- Food effect -- Biopharmaceutical modeling for miscellaneous cases -- Intestinal transporters -- Strategy in drug discovery and development -- Epistemology of biopharmaceutical modeling and good simulation practice.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Source of descriptionDescription based on print version record and CIP data provided by publisher.
Issued in other formPrint version: Sugano, Kiyohiko. Biopharmaceutics modeling and simulations Hoboken, N.J. : John Wiley & Sons, c2013 9781118028681 (cloth)
Genre/formElectronic books.
LCCN 2012008118
ISBN9781118354315 (pdf)
ISBN9781118354322 (epub)
ISBN9781118354308 (mobi)