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016 7 a| 0161905752| Uk;

020 a| 9780123979278 (hbk.);

020 a| 0123979277 (hbk.);

035 a| (WaSeSS)ssj0000736957;

042 a| lccopycat;

049 a| EREEa| NEHH;

050 00 a| RC270.8b| .C864 2012;

082 04 a| 616.994062| 23;

245 00 a| Current chalenges in personalized cancer medicineh| [electronic resource] /c| edited by Keiran S.M. Smalley.;

250 a| First edition.;

260 a| Amsterdam ;a| Boston :b| Academic Press,;

300 a| xviii, 558 p. :b| ill. ;c| 24 cm.;

490 1 a| Advances in pharmacology ( San Diego, Calif.) ;v| 65;

504 a| Includes bibliographical references and index.;

505 0 a| Vertical pathway targeting in cancer therapy -- Histone deacetylases (HDACs) as mediators of resistance to apoptosis in melanoma and as targets for combination therapy with selective BRAF inhibitors -- Targeting the tumor stroma as a novel treatment strategy for breast cancer: shifting from the neoplastic cell-centric to a stroma-centric paradigm -- Targeting the metabolic microenvironment of tumors -- Targeted therapy for brain metastases -- Emerging strategies for targeting cell adhesion in multiple myeloma -- Targeting notch signaling for cancer therapeutic intervention -- Stem-like cells and therapy resistance in squamous cell carcinomas -- Targeting the tumor stroma as a novel therapeutic approach for prostate cancer -- Resistance to chemotherapy: short-term drug tolerance and stem cell-like subpopulations -- Intratumoral heterogeneity as a therapy resistance mechanism: role of melanoma subpopulations -- Chemoprevention of melanoma -- Whole genome and exome sequencing of melanoma: a step toward personalized targeted therapy -- Targeted therapy for gastric adenocarcinoma -- HSP90 inhibitors for cancer therapy and overcoming drug resistance -- Apoptosis in targeted therapy responses: the role of BIM.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Pharmacology.=| ^A255;

650 0 a| Cancerx| Treatment.=| ^A13628;

650 12 a| Individualized Medicinex| methods.?| UNAUTHORIZED;

650 12 a| Neoplasmsx| genetics.=| ^A920613;

650 12 a| Neoplasmsx| therapy.=| ^A918606;

650 22 a| Molecular Targeted Therapyx| methods.=| ^A1289122;

650 22 a| Targeted Gene Repairx| methods.?| UNAUTHORIZED;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Smalley, Keiran S. M.?| UNAUTHORIZED;

830 0 a| Advances in pharmacology (San Diego, Calif.) ;v| 65.x| 1054-3589=| ^A932989;

856 40 z| Full text available from Book Series Package - Life Sciences [BSLFSC]u| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbookseries%2F10543589%2F65;

947 a| (OCoLC)ocn802322404;

949 a| CLICK ON WEB ADDRESSw| ASISh| JOYNER188;

949 a| CLICK ON WEB ADDRESSw| ASISh| HSL77;

949 a| CLICK ON WEB ADDRESSw| ASISh| JMUSIC60;

596 a| 1 3 4;

998 a| 4036345;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4036345-1001l| JNETm| JOYNERr| Ys| Yt| JNESSBKu| 1/1/2016x| EBOOKz| JERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4036345-2001l| HSLELECm| HSLr| Ys| Yt| HEBKu| 1/1/2016x| EBOOKz| HERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4036345-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 1/1/2016x| EBOOKz| JERESOURCE;

Current chalenges in personalized cancer medicine / edited by Keiran S.M. Smalley.

Other author	Smalley, Keiran S. M.
Format	Electronic
Edition	First edition.
Publication Info	Amsterdam ; Boston : Academic Press,
Description	xviii, 558 p. : ill. ; 24 cm.
Supplemental Content	Full text available from Book Series Package - Life Sciences [BSLFSC]
Subjects	Pharmacology. Cancer--Treatment. Individualized Medicine--methods. Neoplasms--genetics. Neoplasms--therapy. Molecular Targeted Therapy--methods. Targeted Gene Repair--methods.

Series	Advances in pharmacology ( San Diego, Calif.) ; 65 Advances in pharmacology (San Diego, Calif.) ; 65. 1054-3589 ^A932989
Contents	Vertical pathway targeting in cancer therapy -- Histone deacetylases (HDACs) as mediators of resistance to apoptosis in melanoma and as targets for combination therapy with selective BRAF inhibitors -- Targeting the tumor stroma as a novel treatment strategy for breast cancer: shifting from the neoplastic cell-centric to a stroma-centric paradigm -- Targeting the metabolic microenvironment of tumors -- Targeted therapy for brain metastases -- Emerging strategies for targeting cell adhesion in multiple myeloma -- Targeting notch signaling for cancer therapeutic intervention -- Stem-like cells and therapy resistance in squamous cell carcinomas -- Targeting the tumor stroma as a novel therapeutic approach for prostate cancer -- Resistance to chemotherapy: short-term drug tolerance and stem cell-like subpopulations -- Intratumoral heterogeneity as a therapy resistance mechanism: role of melanoma subpopulations -- Chemoprevention of melanoma -- Whole genome and exome sequencing of melanoma: a step toward personalized targeted therapy -- Targeted therapy for gastric adenocarcinoma -- HSP90 inhibitors for cancer therapy and overcoming drug resistance -- Apoptosis in targeted therapy responses: the role of BIM.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2012277161
ISBN	9780123979278 (hbk.)
ISBN	0123979277 (hbk.)

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Current chalenges in personalized cancer medicine / edited by Keiran S.M. Smalley.

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