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020 a| 9780387403137 (alk. paper);

020 a| 0387403132 (alk. paper);

020 a| 9780387686363 (e-ISBN);

020 a| 0387686363 (e-ISBN);

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100 1 a| Halloran, M. Elizabeth.=| ^A1007957;

245 10 a| Design and analysis of vaccine studiesh| [electronic resource] /c| M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner.;

260 a| New York :b| Springer,;

300 a| xviii, 387 p. :b| ill. ;c| 24 cm.;

490 1 a| Statistics for biology and health,x| 1431-8776;

504 a| Includes bibliographical references (p. 361-379) and index.;

505 0 a| Overview of vaccine effects and study designs -- Immunology and early phase trials -- Binomial and stochastic transmission models -- R[o] and deterministic models -- Evaluating protective effects of vaccination -- Models of action and time-varying VE[s] -- Further evaluation of protective effects -- Vaccine effects on post-infection outcomes -- Household-based studies -- Analysis of households in communities -- Analysis of independent households -- Assessing indirect, total, and overall effects -- Randomization and baseline transmission -- Surrogates of protection.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Vaccinesx| Research.=| ^A140104;

650 0 a| Vaccinesx| Statistical methods.=| ^A140104;

650 0 a| Epidemiologyx| Research.=| ^A280049;

650 0 a| Case-control method.=| ^A1012345;

650 12 a| Research Design.=| ^A918075;

650 12 a| Vaccines.=| ^A923504;

650 22 a| Clinical Trials as Topic.=| ^A920927;

650 22 a| Drug Evaluationx| methods.=| ^A920949;

650 22 a| Researchx| methods.=| ^A918990;

650 22 a| Statistics as Topic.=| ^A918102;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Longini, Ira M.=| ^A1013150;

700 1 a| Struchiner, Claudio J.=| ^A1013152;

830 0 a| Statistics for biology and health,x| 1431-8776.=| ^A695739;

856 40 z| Full text available from Springer Booksu| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Flink.springer.com%2F10.1007%2F978-0-387-68636-3;

856 40 z| Full text available from Springer Nature - Springer Mathematics and Statistics eBooks 2010 English Internationalu| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Flink.springer.com%2F10.1007%2F978-0-387-68636-3;

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Design and analysis of vaccine studies / M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner.

Author/creator	Halloran, M. Elizabeth
Other author	Longini, Ira M.
Other author	Struchiner, Claudio J.
Format	Electronic
Publication Info	New York : Springer,
Description	xviii, 387 p. : ill. ; 24 cm.
Supplemental Content	Full text available from Springer Books
Supplemental Content	Full text available from Springer Nature - Springer Mathematics and Statistics eBooks 2010 English International
Subjects	Vaccines--Research. Vaccines--Statistical methods. Epidemiology--Research. Case-control method. Research Design. Vaccines. Clinical Trials as Topic. Drug Evaluation--methods. Research--methods. Statistics as Topic.

Series	Statistics for biology and health, 1431-8776 Statistics for biology and health, 1431-8776. ^A695739
Contents	Overview of vaccine effects and study designs -- Immunology and early phase trials -- Binomial and stochastic transmission models -- R[o] and deterministic models -- Evaluating protective effects of vaccination -- Models of action and time-varying VE[s] -- Further evaluation of protective effects -- Vaccine effects on post-infection outcomes -- Household-based studies -- Analysis of households in communities -- Analysis of independent households -- Assessing indirect, total, and overall effects -- Randomization and baseline transmission -- Surrogates of protection.
Bibliography note	Includes bibliographical references (p. 361-379) and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2009938829
ISBN	9780387403137 (alk. paper)
ISBN	0387403132 (alk. paper)
ISBN	9780387686363 (e-ISBN)
ISBN	0387686363 (e-ISBN)

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Library	Location	Call Number	Status	Item Actions
	Electronic Resources	Online Content Full text available from Springer Books Full text available from Springer Books	✔ Available

Design and analysis of vaccine studies / M. Elizabeth Halloran, Ira M. Longini, Jr., Claudio J. Struchiner.

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