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245 00 a| Down syndromeh| [electronic resource] :b| from understanding the neurobiology to therapy /c| edited by Mara Dierssen, Rafael de la Torre.;

250 a| 1st ed.;

260 a| Amsterdam ;a| Boston :b| Elsevier,;

300 a| x, 262 p. :b| ill. ;c| 24 cm.;

490 1 a| Progress in brain research,x| 0079-6123 ;v| v. 197;

504 a| Includes bibliographical references and index.;

505 0 a| Therapeutic approaches in the improvement of cognitive performance in Down syndrome: past, present, and future / R. de la Torre and M. Dierssen -- Genomic determinants in the phenotypic variability of Down syndrome / A. Letourneau and S.E. Antonarakis -- Intellectual disabilities, neuronal posttranscriptional RNA metabolism, and RNA-binding proteins: three actors for a complex scenario / B. Bardoni ... [et al.] -- Aberrant epigenetic landscape in intellectual disability / J.V. Sanchez-Mut, D. Huertas and M. Esteller -- Pathways to cognitive deficits in Down syndrome / X. Sturgeon ... [et al.] -- Neurological phenotypes for Down syndrome across the life span / I.T. Lott -- Human and mouse model cognitive phenotypes in Down syndrome: implications for assessment / J.O. Edgin ... [et al.] -- Perturbation of dendritic protrusions in intellectual disability / J. Levenga and R. Willemsen -- The in vivo Down syndrome genomic library in mouse / Y. Herault ... [et al.] -- Discoveries in Down syndrome: moving basic science to clinical care -- A.M. Kleschevnikov ... [et al.] -- A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome / D.G. Currier, R.C. Polk and R.H. Reeves -- Gene therapy for Down syndrome / C. Fillat and X. Altafaj.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Down syndrome.=| ^A2787;

650 0 a| Developmental neurobiology.=| ^A381784;

650 12 a| Down Syndromex| genetics.=| ^A924246;

650 12 a| Down Syndromex| therapy.=| ^A1202465;

650 22 a| Neurobiology.=| ^A918036;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Dierssen, Mara.?| UNAUTHORIZED;

700 1 a| Torre, Rafael de la.?| UNAUTHORIZED;

830 0 a| Progress in brain researchv| v. 197.x| 0079-6123=| ^A75148;

856 40 z| Full text available from Book Series Package - Life Sciences [BSLFSC]u| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbookseries%2F00796123%2F197;

947 a| (OCoLC)ocn761856423;

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Down syndrome from understanding the neurobiology to therapy / edited by Mara Dierssen, Rafael de la Torre.

Other author	Dierssen, Mara.
Other author	Torre, Rafael de la.
Format	Electronic
Edition	1st ed.
Publication Info	Amsterdam ; Boston : Elsevier,
Description	x, 262 p. : ill. ; 24 cm.
Supplemental Content	Full text available from Book Series Package - Life Sciences [BSLFSC]
Subjects	Down syndrome. Developmental neurobiology. Down Syndrome--genetics. Down Syndrome--therapy. Neurobiology.

Series	Progress in brain research, 0079-6123 ; v. 197 Progress in brain research v. 197. 0079-6123 ^A75148
Contents	Therapeutic approaches in the improvement of cognitive performance in Down syndrome: past, present, and future / R. de la Torre and M. Dierssen -- Genomic determinants in the phenotypic variability of Down syndrome / A. Letourneau and S.E. Antonarakis -- Intellectual disabilities, neuronal posttranscriptional RNA metabolism, and RNA-binding proteins: three actors for a complex scenario / B. Bardoni ... [et al.] -- Aberrant epigenetic landscape in intellectual disability / J.V. Sanchez-Mut, D. Huertas and M. Esteller -- Pathways to cognitive deficits in Down syndrome / X. Sturgeon ... [et al.] -- Neurological phenotypes for Down syndrome across the life span / I.T. Lott -- Human and mouse model cognitive phenotypes in Down syndrome: implications for assessment / J.O. Edgin ... [et al.] -- Perturbation of dendritic protrusions in intellectual disability / J. Levenga and R. Willemsen -- The in vivo Down syndrome genomic library in mouse / Y. Herault ... [et al.] -- Discoveries in Down syndrome: moving basic science to clinical care -- A.M. Kleschevnikov ... [et al.] -- A Sonic hedgehog (Shh) response deficit in trisomic cells may be a common denominator for multiple features of Down syndrome / D.G. Currier, R.C. Polk and R.H. Reeves -- Gene therapy for Down syndrome / C. Fillat and X. Altafaj.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2012471162
ISBN	9780444542991
ISBN	044454299X

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Down syndrome from understanding the neurobiology to therapy / edited by Mara Dierssen, Rafael de la Torre.

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