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020 a| 9780123738837 (hbk);

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245 00 a| Genetic dissection of complex traitsh| [electronic resource] /c| edited by D.C. Rao, C. Charles Gu.;

250 a| 2nd ed.;

260 a| Amsterdam ;a| Boston :b| Elsevier/Academic Press,;

300 a| xxvii, 760 p. :b| ill. ;c| 24 cm.;

490 1 a| Advances in genetics,x| 0065-2660 ;v| v. 60;

504 a| Includes bibliographical references and Index.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 12 a| Genetics, Medicalx| methods=| ^A927435;

650 22 a| Genetic Diseases, Inborn=| ^A936142;

650 22 a| Genetic Linkage=| ^A950894;

650 22 a| Genetic Predisposition to Disease=| ^A932601;

650 22 a| Models, Genetic=| ^A927393;

650 22 a| Quantitative Trait, Heritable=| ^A1337310;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Rao, D. C.q| (Dabeeru C.)?| UNAUTHORIZED;

700 1 a| Gu, C. Charles.?| UNAUTHORIZED;

830 0 a| Advances in genetics,v| v. 60.=| ^A669023;

856 40 z| Full text available from Book Series Package - Life Sciences [BSLFSC]u| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbookseries%2F00652660%2F60;

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Genetic dissection of complex traits / edited by D.C. Rao, C. Charles Gu.

Other author	Rao, D. C. (Dabeeru C.)
Other author	Gu, C. Charles.
Format	Electronic
Edition	2nd ed.
Publication Info	Amsterdam ; Boston : Elsevier/Academic Press,
Description	xxvii, 760 p. : ill. ; 24 cm.
Supplemental Content	Full text available from Book Series Package - Life Sciences [BSLFSC]
Subjects	Genetics, Medical--methods. Genetic Diseases, Inborn Genetic Linkage Genetic Predisposition to Disease Models, Genetic Quantitative Trait, Heritable

Series	Advances in genetics, 0065-2660 ; v. 60 Advances in genetics, v. 60. ^A669023
Contents	1. An overview of the genetic dissection of complex traits / D. C. Rao -- 2. Familial resemblance and heritability / Treva K. Rice -- 3. Linkage and association: basic concepts / Ingrid B. Borecki and Michael A. Province -- 4. Definition of phenotype / Mary K. Wojczynski and Hemant K. Tiwari -- 5. Genotyping platforms for mass-throughput genotyping with SNPs, including human genome-wide scans / Karen Maresso and Ulrich Broeckel -- 6. Genotyping errors and their impact on genetic analysis / Michael B. Miller, Karen Schwander, and D. C. Rhao -- 7. Model-based methods for linkage analysis / John P. Rice, Nancy L. Saccone, and Jonathan Corbett -- 8. Contemporary model-free methods for linkage analysis / Laura Almasy and John Blangero -- 9. DNA sequence-based phenotypic association analysis / Nicholas J. Schork, Jennifer Wessel, and Nathalie Malo --
Contents	10. Family-based methods for linkage and association analysis / Nan M. Laird and Christoph Lange -- 11. Searching for additional disease loci in a genomic region / Glenys Thomson, Lisa F. Barcellos, and Ana M. Valdes -- 12. Methods for handling multiple testing / Treva K. Rice, Nicholas J. Schork, and D. C. Rao -- 13. Meta-analysis methods / Thomas A. Trikalinos, Georgia Salanti, Eias Zintzaras, and John P. A. Ioannidis -- 14. Haplotype-association analysis / Nianjun Liu, Kui Zhang, and Hongyu Zhao -- 15. Characterization LD structures and the utility of HapMap in genetic association studies / C. Charles Gu, Kai Yu, and D. C. Rao -- 16. Associations among multiple markers and complex disease: models, algorithms, and applications / Themistocles L. Assimes, Adam B. Olshen, Balasubramanian Narasimhan, and Richard A. Olshen --
Contents	17. Study designs for genome-wide association studies / Peter Kraft and David G. Cox -- 18. Ethical, legal, and social implications of biobanks for genetics research / Susanne B. Haga and Laura M. Beskow -- 19. Admixture mapping and the role of population structure for localizing disease genes / Xiaofeng Zhu, Hua Tang, and Neil Risch -- 20. Integrating global gene expression analysis and genetics / Clarles R. Farber and Aldons J. Lusis -- 21. A systems biology approach to drug discovery / Jun Zhu, Bin Zhang, and Eric E. Schadt -- 22. The promise of composite likelihood methods for addressing computationally intensive challenges / Na Li -- 23 Comparative genomics for detecting human disease genes / Carol Moreno, Jozef Lazar, Howard J. Jacob, and Anne E. Kwitek -- 24. From genetics to mechanism of disease liability / Andreas Rohrwasser, Paul Lott, Robert B. Weiss, and Jean-Marc Lalouel -- 25. Into the Post-HapMap era / Newton E. Morton.
Bibliography note	Includes bibliographical references and Index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
ISBN	9780123738837 (hbk)
ISBN	0123738830 (hbk)

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