Genome organization and function in the cell nucleus / edited by Karsten Rippe.

Other author Rippe, Karsten.
Format Electronic
Publication InfoWeinheim : Wiley-VCH,
Descriptionxxv, 568 pages : illustrations ; 25 cm
Supplemental ContentFull text available from Ebook Central - Academic Complete
Subjects

Contents Front Matter -- Deciphering DNA Sequence Information / Mark Kaganovich, Michael Snyder -- DNA Methylation / Carina Frauer, Fabio Spada, Heinrich Leonhardt -- Nucleosomes as Control Elements for Accessing the Genome / Mekonnen Lemma Dechassa, Karolin Luger -- Histone Modifications and Their Role as Epigenetic Marks / Karl Nightingale -- Chromatin Remodeling and Nucleosome Positioning / Gernot L̃ngst, Vladimir B Teif, Karsten Rippe -- The Folding of the Nucleosome Chain / Karsten Rippe -- The Crowded Environment of the Genome / Ron Hancock -- The Nuclear Lamina as a Chromatin Organizer / Nikolaj Zuleger, Eric C Schirmer -- Three-Dimensional Architecture of Genomes / Job Dekker -- Transcriptional Initiation: Frequency, Bursting, and Transcription Factories / Kieran Finan, Peter R Cook -- Processing of mRNA and Quality Control / Ute Schmidt, Edouard Bertrand -- The Nucleolus / Saskia Hutten, Belinda J Westman, Fraṅois-Michel Boisvert, Silvana van Koningsbruggen, Angus I Lamond -- Non-Coding RNAs as Regulators of Transcription and Genome Organization / Katalin Fejes T̤th, Gregory Hannon -- RNA Networks as Digital Control Circuits of Nuclear Functions / John S Mattick -- DNA Replication and Inheritance of Epigenetic States / Armelle Corpet, Genevïve Almouzni -- Interplay and Quality Control of DNA Damage Repair Mechanisms / Berina Eppink, Jeroen Essers, Roland Kanaar -- Higher Order Chromatin Organization and Dynamics / Hilmar Strickfaden, Thomas Cremer, Karsten Rippe -- The Mitotic Chromosome: Structure and Mechanics / John F Marko -- Meiotic Chromosome Dynamics / Nancy Kleckner, Liangran Zhang, Beth Weiner, Denise Zickler -- Understanding Genome Function: Quantitative Modeling of Chromatin Folding and Chromatin-Associated Processes / Mariliis Tark-Dame, Martijn S Luijsterburg, Dieter W Heermann, Roel van Driel -- Index.
Abstract By way of its clear and logical structure, as well as abundant highresolution illustrations, this is a systematic survey of the players and pathways that control genome function in the mammalian cell nucleus. As such, this handbook and reference ties together recently gained knowledge from a variety of scientific disciplines and approaches, dissecting all major genomic events: transcription, replication, repair, recombination and chromosome segregation. A special emphasis is put on transcriptional control, including genome-wide interactions and non-coding RNAs, chromatin structure, epigenetics and nuclear organization. With its focus on fundamental mechanisms and the associated biomolecules, this will remain essential reading for years to come.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2023302589
ISBN9783527326983 (hardback ; alk. paper)
ISBN3527326987 (hardback ; alk. paper)
ISBN(ePDF)
ISBN(oBook)
ISBN(ePub)
ISBN(Mobi)
ISBN(ePDF)
ISBN(oBook)
ISBN(ePub)
ISBN(Mobi)
Standard identifier# 9783527326983
Publisher numberBest.-Nr.: 1132698 000

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