Improving the quality of cancer clinical trials workshop summary / National Cancer Policy Forum, Margie Patlack and Sharyl Nass, Rapporteurs.
| Format | Electronic |
| Publication Info | Washington, D.C. : National Academies Press, |
| Description | xii, 124 p. : ill. (some col.) ; 23 cm. |
| Supplemental Content | Full text available from Ebook Central - Academic Complete |
| Subjects |
| Other author/creator | Patlak, Margie. |
| Other author/creator | Nass, Sharyl J. |
| Other author/creator | National Cancer Policy Forum (U.S.) |
| Other author/creator | Institute of Medicine (U.S.) |
| Contents | Introduction -- New clinical trial designs. Phase 0 trials -- Adaptive trial designs -- Targeting multiple pathways with multiple drugs -- Preclinical model systems -- Molecular imaging. Current and developing methods -- Challenges of molecular imaging -- Screening for predictive markers. The challenges of clinical validation -- Bioimaging predictive markers -- Clinical translation -- Panel discussion -- Costs of clinical trials. Regulatory costs -- Patient accrual -- Global outsourcing -- Time is money -- Public-private collaborations -- Regulatory issues. Regulatory barriers to innovation -- Patient advocacy perspective -- Regulation of in vitro diagnostics -- Regulatory issues in improving cancer clinical trials -- Reports from the case study discussion groups. Adaptive trial design -- Phase 0 trials -- Imaging -- Use of proteomics/genomics to assign therapy in lung cancer -- Use of genetics/genomics to assign therapy. |
| Bibliography note | Includes bibliographical references. |
| Access restriction | Available only to authorized users. |
| Other forms | Also available on the World Wide Web. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| LCCN | 2008299448 |
| ISBN | 9780309116688 |
| ISBN | 0309116686 |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |