An introduction to statistics in early phase trials / Steven A. Julious, Say Beng Tan, David Machin.

Author/creator Julious, Steven A.
Other author Machin, David, 1939-
Other author Tan, Say Beng.
Format Electronic
Publication InfoThe Atrium, Southern Gate, Chichester, West Sussex, UK ; Hoboken, NJ : Wiley-Blackwell,
Description263 p. : ill. ; 26 cm.
Supplemental ContentFull text available from Ebook Central - Academic Complete
Subjects
Drugs--Testing. --Statistical methods.
Clinical trials--Statistical methods.
Clinical Trials, Phase I as Topic--methods.
Biometry--methods.
Clinical Trials, Phase II as Topic--methods.
Models, Statistical.
Statistics as Topic--methods.

Contents Early phase trials -- Introduction to pharmacokinetics -- Sample size calculations for clinical trials -- Crossover trial basics -- Multi-period crossover trials -- First time into man -- Bayesian and frequentist methods -- First-time-into-new-population studies -- Bioequivalence studies -- Other phase I trials -- Phase II trials : general issues -- Dose-response studies -- Phase II trials with toxic therapies -- Interpreting and applying early phase trial results -- Go/no-go criteria.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2009033763
ISBN9780470059852
ISBN0470059850

Availability

Library Location Call Number Status Item Actions
Electronic Resources Access Content Online ✔ Available