Lead generation approaches in drug discovery / [edited by] Zoran Rankovic, Richard Morphy.

Other author Rankovic, Zoran.
Other author Morphy, Richard.
Format Electronic
Publication InfoHoboken, N.J. : John Wiley,
Descriptionxi, 295 p. : ill. ; 25 cm.
Supplemental ContentFull text available from Ebook Central - Academic Complete
Subjects
Drug development.
Drugs--Design.
High throughput screening (Drug development)
Drug Discovery--methods.

Contents Lead discovery : the process / William F. Michne -- High throughput screening approach to lead discovery / Zoran Rankovic, Craig Jamieson, and Richard Morphy -- In silico screening / Dagmar Stumpfe, Hanna Geppert, and Jürgen Bajorath -- Fragment-based lead discovery / Jeffrey S. Albert -- Design of multitarget ligands / Richard Morphy and Zoran Rankovic -- De novo drug design / Gisbert Schneider, Markus Hartenfeller, Ewgenij Proschak -- Role of natural products in drug discovery / Hugo Lachance, Stefan Wetzel, and Herbert Waldmann -- Early screening for ADMET properties / Dennis A. Smith -- Role of chemistry in lead discovery / Roland E. Dolle and Karin Worm.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2009040188
ISBN9780470257616 (cloth)
ISBN047025761X (cloth)