Chirality from Dynamic Kinetic Resolution

Author/creator Pellissier, Hélène Author
Format Electronic
Publication InfoCambridge : Royal Society of Chemistry, The LaVergne : Ingram Publisher Services [Distributor]
Description318 p. ill 23.400 x 015.600 cm.
Supplemental ContentFull text available from Ebook Central - Academic Complete
Subjects

Summary Annotation <div>The last 15 years have witnessed significant developments in the efficiency and scope of the application of DKR. These now offer a serious alternative to conventional methods for asymmetric synthesis. Indeed, impressive examples using new enzymes and major progress in the DKR of racemates have taken place over the past few years. The powerful combination of enzymes and metals has also been the subject of spectacular development. In addition, a new type of DKR, involving organocatalysts, has recently appeared. Although asymmetric catalysis has undergone development during the last two decades, the most common industrial process used to obtain enantiomerically pure compounds is still via resolution of racemic mixtures. This is despite the major disadvantage that only a maximum of 50% product yield can be obtained. It is not surprising that DKR, which solves the problem of the limitation in yield, has attracted an increasing amount of interest from both the industrial and the academic perspective. This book provides an up-date on the principle methods employed to obtain dynamic kinetic resolution (DKR) by either enzymatic or non-enzymatic methods. It also illustrates the diversity of useful chiral products that can be obtained through this powerful concept. Divided into three sections, the book deals successively with non-enzymatic methods, enzymatic methods, and the use of transition metals and enzymes in tandem.</div>
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
ISBN9781849731973
ISBN1849731977 (Trade Cloth) Active Record
Standard identifier# 9781849731973
Stock number00154291

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