Kelley and Firestein's textbook of rheumatology / [edited by] Gary S. Firestein, MD, Distinguished Professor of Medicine, Dean and Associate Vice Chancellor, Translational Medicine, University of California, San Diego School of Medicine, La Jolla, California, Ralph C. Budd, MD, Professor of Medicine and Microbiology and Molecular Genetics, Director, Vermont Center for Immunology and Infectious Diseases, University of Vermont College of Medicine Distinguished University Professor, The University of Vermont College of Medicine, Burlington, Vermont, Sherine E. Gabriel, MD, MSc, Professor and Dean, Rutgers Robert Wood Johnson Medical School, CEO, Robert Wood Johnson Medical Group, Emeritus Professor, Mayo Clinic, New Brunswick, New Jersey, Iain B. McInnes, PhD, FRCP, FRSE, FMedSci, Muirhead Professor of Medicine, Arthritis Research UK Professor of Rheumatology, Director of Institute of Infection, Immunity, and Inflamation, College of Medical, Veterinary, and Life Sciences, University of Glasgow, Glasgow, United Kingdom, James R. O'Dell, MD, Bruce Professor and Vice Chair of Internal Medicine, University of Nebraska Medical Center, Chief of Rheumatology, Department of Medicine, Omaha Veterans Affairs, Omaha, Nebraska.