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010 a| 2007045553;

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020 a| 9780470018774 (cloth : alk. paper);

020 a| 0470018771 (cloth : alk. paper);

035 a| (WaSeSS)ssj0000251055;

042 a| pcc;

049 a| EREEa| NEHH;

050 00 a| RM301.25b| .S46 2007;

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100 1 a| Senn, Stephen.=| ^A812732;

245 10 a| Statistical issues in drug developmenth| [electronic resource] /c| Stephen Senn.;

250 a| 2nd ed.;

260 a| Chichester, England ;a| Hoboken, NJ :b| John Wiley & Sons,;

300 a| xix, 498 p. :b| ill. ;c| 25 cm.;

440 0 a| Statistics in practice;

504 a| Includes bibliographical references and index.;

505 0 a| A brief and superficial history of statistics for drug developers -- Design and interpretation of clinical trials as seen by a statistician -- Probability, Bayes, P-values, tests of hypotheses, and confidence intervals -- The work of the pharmaceutical statistician -- Allocating treatments to patients in clinical trials -- Baselines and covariate information --;

505 0 a| The measurement of treatment effects -- Demographic subgroups : representation and analysis -- Multiplicity -- Intention to treat, missing data and related matters -- One-sided and two-sided tests and other issues to do with significance and P-values -- Determining the sample size -- Multicentre trials -- Active control equivalence studies --;

505 0 a| Meta-analysis -- Cross-over trials -- n-of-1 trials -- Sequential trials -- Dose-finding -- Concerning pharmacokinetics and pharmacodynamics -- Bioequivalence studies -- Safety data, harms, drug monitoring, and pharmaco-epidemiology -- Pharmaco-economics and portfolio management -- Concerning pharmacogenetics, pharmacogenomics, and related matters.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Drug developmentx| Statistical methods.=| ^A443888;

650 12 a| Clinical Trials as Topic.=| ^A920927;

650 22 a| Drug Design.=| ^A925973;

650 22 a| Statistics as Topicx| methods.=| ^A919341;

655 0 a| Electronic books.=| ^A491897;

856 40 z| Full text available from eBooks on EBSCOhostu| https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=233276&scope=site&custid=s5822723&authtype=ip,shib;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=351458;

947 a| (OCoLC)ocn180907943;

947 a| (OCoLC)180907943;

949 a| CLICK ON WEB ADDRESSw| ASISh| JOYNER188;

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949 a| CLICK ON WEB ADDRESSw| ASISh| JMUSIC60;

596 a| 1 3 4;

998 a| 4638739;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4638739-1001l| JNETm| JOYNERr| Ys| Yt| JNESSBKu| 3/2/2017x| EBOOKz| JERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4638739-2001l| HSLELECm| HSLr| Ys| Yt| HEBKu| 3/2/2017x| EBOOKz| HERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4638739-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 3/2/2017x| EBOOKz| JERESOURCE;

Statistical issues in drug development / Stephen Senn.

Author/creator	Senn, Stephen
Format	Electronic
Edition	2nd ed.
Publication Info	Chichester, England ; Hoboken, NJ : John Wiley & Sons,
Description	xix, 498 p. : ill. ; 25 cm.
Supplemental Content	Full text available from eBooks on EBSCOhost
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Drug development--Statistical methods. Clinical Trials as Topic. Drug Design. Statistics as Topic--methods.

Series	Statistics in practice
Contents	A brief and superficial history of statistics for drug developers -- Design and interpretation of clinical trials as seen by a statistician -- Probability, Bayes, P-values, tests of hypotheses, and confidence intervals -- The work of the pharmaceutical statistician -- Allocating treatments to patients in clinical trials -- Baselines and covariate information --
Contents	The measurement of treatment effects -- Demographic subgroups : representation and analysis -- Multiplicity -- Intention to treat, missing data and related matters -- One-sided and two-sided tests and other issues to do with significance and P-values -- Determining the sample size -- Multicentre trials -- Active control equivalence studies --
Contents	Meta-analysis -- Cross-over trials -- n-of-1 trials -- Sequential trials -- Dose-finding -- Concerning pharmacokinetics and pharmacodynamics -- Bioequivalence studies -- Safety data, harms, drug monitoring, and pharmaco-epidemiology -- Pharmaco-economics and portfolio management -- Concerning pharmacogenetics, pharmacogenomics, and related matters.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2007045553
ISBN	9780470018774 (cloth : alk. paper)
ISBN	0470018771 (cloth : alk. paper)

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Library	Location	Call Number	Status	Item Actions
	Electronic Resources	Online Content Full text available from eBooks on EBSCOhost Full text available from Ebook Central - Academic Complete	✔ Available

Statistical issues in drug development / Stephen Senn.

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