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245 00 a| Molecular and cellular therapies for motor neuron diseasesh| [electronic resource] /c| edited by Nicholas Boulis, Deirdre O'Connor, and Anthony Donsante.;

260 a| London :b| Elsevier, Academic Press,c| [2017].;

300 a| xiii, 321 pages :b| illustrations ;c| 24 cm;

504 a| Includes bibliographical references and index.;

505 0 a| 1. Molecular and extracellular cues in motor neuron specification and differentiation / R.L. Swetenburg, S.L. Stice and L. Karumbaiah -- 2. Natural history of amyotrophic lateral sclerosis / M.J. Magnussen and J.D. Glass -- 3. Genetics of amyotrophic lateral sclerosis / K.P. Kenna, J.E. Landers and N. Ticozzi -- 4. Molecular mechanisms of amytrophic lateral sclerosis / M. Collins and R. Bowser -- 5. An introduction to natural history, genetic mapping, and clinical spectrum of spinal muscular atrophy / A. McDonough, L. Urquia and N. Boulis -- 6. Genetics of spinal muscular atrophy / A.H.M. Burghes and V.L. McGovern -- 7. Introduction to gene and stem-cell therapy / D.M. O'Connor -- 8. Gene therapy for amytrophic lateral sclerosis / A. Dosante -- 9. Stem cell therapy for amytrophic lateral sclerosis / K.S. Chen and E.L. Feldman -- 10. Gene therapy for spinal muscular atrophy / M.R. Miller, E.Y. Osman and C.L. Lorson -- 11. Cellular therapy for spinal muscular atrophy / I. Faravelli and S. Corti -- 12. Clinical trials to date / B.J. Mader and N. Boulis.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Motor neuronsx| Diseasesx| Treatment.=| ^A1000066;

650 0 a| Neuromuscular diseasesx| Treatment.=| ^A4270;

650 12 a| Motor Neuron Diseasex| therapy.=| ^A962067;

650 22 a| Molecular Targeted Therapyx| methods.=| ^A1289122;

650 22 a| Cell- and Tissue-Based Therapyx| methods.=| ^A1205596;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Boulis, Nicholas.=| ^A1359076;

700 1 a| O'Connor, Deirdreq| (Deirdre M.)=| ^A1359077;

700 1 a| Donsante, Anthony.=| ^A1359078;

856 40 z| Full text available from ClinicalKey Flexu| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fwww.clinicalkey.com%2Fdura%2Fbrowse%2FbookChapter%2F3-s2.0-C20140018941;

947 a| (OCoLC)ocn956959080;

949 a| CLICK ON WEB ADDRESSw| ASISh| JOYNER188;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4843882-2001l| HSLELECm| HSLr| Ys| Yt| HEBKu| 4/20/2018x| EBOOKz| HERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4843882-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 4/20/2018x| EBOOKz| JERESOURCE;

Molecular and cellular therapies for motor neuron diseases / edited by Nicholas Boulis, Deirdre O'Connor, and Anthony Donsante.

Other author	Boulis, Nicholas.
Other author	O'Connor, Deirdre (Deirdre M.)
Other author	Donsante, Anthony.
Format	Electronic
Publication Info	London : Elsevier, Academic Press, [2017].
Description	xiii, 321 pages : illustrations ; 24 cm
Supplemental Content	Full text available from ClinicalKey Flex
Subjects	Motor neurons--Diseases. --Treatment. Neuromuscular diseases--Treatment. Motor Neuron Disease--therapy. Molecular Targeted Therapy--methods. Cell- and Tissue-Based Therapy--methods.

Contents	1. Molecular and extracellular cues in motor neuron specification and differentiation / R.L. Swetenburg, S.L. Stice and L. Karumbaiah -- 2. Natural history of amyotrophic lateral sclerosis / M.J. Magnussen and J.D. Glass -- 3. Genetics of amyotrophic lateral sclerosis / K.P. Kenna, J.E. Landers and N. Ticozzi -- 4. Molecular mechanisms of amytrophic lateral sclerosis / M. Collins and R. Bowser -- 5. An introduction to natural history, genetic mapping, and clinical spectrum of spinal muscular atrophy / A. McDonough, L. Urquia and N. Boulis -- 6. Genetics of spinal muscular atrophy / A.H.M. Burghes and V.L. McGovern -- 7. Introduction to gene and stem-cell therapy / D.M. O'Connor -- 8. Gene therapy for amytrophic lateral sclerosis / A. Dosante -- 9. Stem cell therapy for amytrophic lateral sclerosis / K.S. Chen and E.L. Feldman -- 10. Gene therapy for spinal muscular atrophy / M.R. Miller, E.Y. Osman and C.L. Lorson -- 11. Cellular therapy for spinal muscular atrophy / I. Faravelli and S. Corti -- 12. Clinical trials to date / B.J. Mader and N. Boulis.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2016944633
ISBN	9780128022573
ISBN	0128022574

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Molecular and cellular therapies for motor neuron diseases / edited by Nicholas Boulis, Deirdre O'Connor, and Anthony Donsante.

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