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007 cr unu||||||||;

008 181015s2018 ncua obm 000 0 eng d;

035 a| (Sirsi) o1056953829;

035 a| (OCoLC)1056953829;

049 a| EREE;

090 a| TA357.5.D37;

100 1 a| Agarwal, Ritesh,e| author.?| UNAUTHORIZED;

245 10 a| Passive micromixers for DNA analysis using CFD modelling /c| by Ritesh Agarwal.;

264 1 a| [Greenville, N.C.] :b| [East Carolina University],c| 2018.;

300 a| 90 pages :b| illustrations(some color);

336 a| textb| txt2| rdacontent;

337 a| computerb| c2| rdamedia;

338 a| online resourceb| cr2| rdacarrier;

347 a| text fileb| PDFc| 1.761 MB2| rda;

538 a| System requirements: Adobe Reader.;

538 a| Mode of access: World Wide Web.;

502 b| M.S.c| East Carolina Universityd| 2018.;

500 a| Presented to the faculty of the Department of Engineering;

500 a| Advisor: Tarek Abdel-Salam;

500 a| Title from PDF t.p. (viewed December 7, 2018).;

520 3 a| Mixing efficiency is an important issue in the design of micromixers, since effective mixing is required between Deoxyribonucleic acid (DNA) sample and restriction enzyme for a fast digestion process. Mixing is improved by chaotic advection through serpentine mixing channels. This leads to the desired reduction in the fluid diffusion path while at the same time increasing the fluid contact areas. The purpose of this research is to evaluate mixing efficiency in microchannel mixers, through a numerical study of different micromixing configuration. To accomplish this, a numerical study is conducted using computational fluid dynamics (CFD) approach using ANSYS Fluent and CFX Software for different geometries designed. Different geometric configuration were proposed and used: bottleneck near the inlet and along the zig zag and curved shaped rectangular zig zag geometry. Mixing analysis is done by different conditions such as Reynold's number, effect of geometry on fluid flow and different diffusion coefficients by evaluating mixing index of the fluid. Results have shown better and faster mixing index around bottleneck region compared to other. This geometry can be used to model passive micromixers and other microfluidic devices with shorter mixing length and for faster mixing between reagents.;

504 a| Includes bibliographical references.;

650 0 a| Computational fluid dynamics.=| ^A367780;

653 a| Numerical Analysis;

653 a| passive micromixer;

700 1 a| Abdel-Salam, Tarek,e| degree supervisor.?| UNAUTHORIZED;

710 2 a| East Carolina University.b| Department of Engineering.=| ^A1231592;

856 40 z| Access via ScholarShipu| http://hdl.handle.net/10342/6944;

949 o| wjh;

994 a| C0b| ERE;

596 a| 1 4;

998 a| 4931012;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4931012-1001l| JNETm| JOYNERr| Ys| Yt| JNE3ETDu| 10/15/2018x| ETDz| JERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4931012-2001l| HSLELECm| HSLr| Ys| Yt| HEETDu| 10/15/2018x| ETDz| HERESOURCE;

Passive micromixers for DNA analysis using CFD modelling / by Ritesh Agarwal.

Author/creator	Agarwal, Ritesh author.
Other author	Abdel-Salam, Tarek, degree supervisor.
Other author	East Carolina University. Department of Engineering.
Format	Theses and dissertations
Publication	[Greenville, N.C.] : [East Carolina University], 2018.
Description	90 pages : illustrations(some color)
Supplemental Content	Access via ScholarShip
Subjects	Computational fluid dynamics.

Summary	Mixing efficiency is an important issue in the design of micromixers, since effective mixing is required between Deoxyribonucleic acid (DNA) sample and restriction enzyme for a fast digestion process. Mixing is improved by chaotic advection through serpentine mixing channels. This leads to the desired reduction in the fluid diffusion path while at the same time increasing the fluid contact areas. The purpose of this research is to evaluate mixing efficiency in microchannel mixers, through a numerical study of different micromixing configuration. To accomplish this, a numerical study is conducted using computational fluid dynamics (CFD) approach using ANSYS Fluent and CFX Software for different geometries designed. Different geometric configuration were proposed and used: bottleneck near the inlet and along the zig zag and curved shaped rectangular zig zag geometry. Mixing analysis is done by different conditions such as Reynold's number, effect of geometry on fluid flow and different diffusion coefficients by evaluating mixing index of the fluid. Results have shown better and faster mixing index around bottleneck region compared to other. This geometry can be used to model passive micromixers and other microfluidic devices with shorter mixing length and for faster mixing between reagents.
General note	Presented to the faculty of the Department of Engineering
General note	Advisor: Tarek Abdel-Salam
General note	Title from PDF t.p. (viewed December 7, 2018).
Dissertation note	M.S. East Carolina University 2018.
Bibliography note	Includes bibliographical references.
Technical details	System requirements: Adobe Reader.
Technical details	Mode of access: World Wide Web.

Passive micromixers for DNA analysis using CFD modelling / by Ritesh Agarwal.

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