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130 0 a| Antibody-drug conjugates (Olivier)?| UNAUTHORIZED;

245 10 a| Antibody-drug conjugatesh| [electronic resource] :b| fundamentals, drug development, and clinical outcomes to target cancer /c| edited by Kenneth J. Olivier Jr., Sara A. Hurvitz.;

260 a| Hoboken, New Jersey :b| John Wiley & Sons, Inc.,c| [2017];

300 a| 1 online resource.;

504 a| Includes bibliographical references and index.;

505 0 a| Typical antibody-drug conjugates / John Lambert -- Selecting optimal ADC targets using indication-dependent or indication-independent approaches / Robert Hollingsworth and Jay Harper -- Antibody drug conjugates : an overview of the CMC and characterization process / Janet Wolfe and Phillip Ross -- Linker and conjugation technology and improvements / Riley Ennis and Sourav Sinha -- Formulation and stability / Kouhei Tsumoto, Anthony Young, and Satoshi Ohtake -- QC assay development / Xiao-Hong Chen and Mate Tolnay -- Occupational health and safety aspects of ADCs and their toxic payloads / Robert Sussman and John Farris -- Bioanalytical strategies enabling successful ADC translation / Xiaogang Han, Lindsay King, and Steve Hansel -- Nonclinical pharmacology and mechanistic modeling of antibody drug conjugates in support of human clinical trials / Brian J. Schmidt, Chin Pan, Heather E. Vezina, Huadong Sun, Douglas D. Leipold, and Manish Gupta -- Pharmacokinetics of antibody-drug conjugates / Amrita Kamath -- Path to market approval : regulatory perspective of ADC nonclinical safety assessments / Stacey Ricci and Natalie Simpson -- Antibody drug conjugates : clinical strategies and applications / Heather E. Vezina, Lucy Lee, Brian J. Schmidt, Manish Gupta -- Antibody-drug conjugates (ADCs) in clinical development / Patricia LoRusso and Joseph McLaughlin -- ADCs approved for use : Trastuzumab emtansine (Kadcyla, T-DM1) in patients with previously treated HER2-positive metastatic breast cancer / Gail Lewis Phillips, Sanne de Hass, Sandhya Girish, and Ellie Guardino -- ADCs approved for use : Brentuximab Vedotin / Sven DeVos and Monica Mead -- Radioimmunotherapy / Jeffrey Wong and Savita Dandapani -- Radiolabeled antibody-based imaging in clinical oncology / Bart Hendriks and Daniel Gaddy -- Antibody-drug conjugates : the next evolution in the cure for cancer -- William C. Olson and Amy Q. Han.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

588 a| Description based on print version record and CIP data provided by publisher.;

650 12 a| Immunoconjugates=| ^A1337251;

650 12 a| Antibodies, Monoclonal=| ^A921952;

650 22 a| Antineoplastic Agents=| ^A918039;

650 22 a| Neoplasmsx| drug therapy=| ^A918295;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Olivier, Kenneth J.,c| Jr.,d| 1968-?| UNAUTHORIZED;

700 1 a| Hurvitz, Sara A.,d| 1970-?| UNAUTHORIZED;

776 08 i| Print version:d| Hoboken, New Jersey : John Wiley & Sons, Inc., [2017]z| 9781119060680w| (DLC) 2016032954;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=4745624;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 4949570-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 11/28/2018x| EBOOKz| JERESOURCE;

Antibody-drug conjugates fundamentals, drug development, and clinical outcomes to target cancer / edited by Kenneth J. Olivier Jr., Sara A. Hurvitz.

Other author	Olivier, Kenneth J., Jr., 1968-
Other author	Hurvitz, Sara A., 1970-
Format	Electronic
Publication Info	Hoboken, New Jersey : John Wiley & Sons, Inc., [2017]
Description	1 online resource.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Immunoconjugates Antibodies, Monoclonal Antineoplastic Agents Neoplasms--drug therapy.

Uniform title	Antibody-drug conjugates (Olivier)
Contents	Typical antibody-drug conjugates / John Lambert -- Selecting optimal ADC targets using indication-dependent or indication-independent approaches / Robert Hollingsworth and Jay Harper -- Antibody drug conjugates : an overview of the CMC and characterization process / Janet Wolfe and Phillip Ross -- Linker and conjugation technology and improvements / Riley Ennis and Sourav Sinha -- Formulation and stability / Kouhei Tsumoto, Anthony Young, and Satoshi Ohtake -- QC assay development / Xiao-Hong Chen and Mate Tolnay -- Occupational health and safety aspects of ADCs and their toxic payloads / Robert Sussman and John Farris -- Bioanalytical strategies enabling successful ADC translation / Xiaogang Han, Lindsay King, and Steve Hansel -- Nonclinical pharmacology and mechanistic modeling of antibody drug conjugates in support of human clinical trials / Brian J. Schmidt, Chin Pan, Heather E. Vezina, Huadong Sun, Douglas D. Leipold, and Manish Gupta -- Pharmacokinetics of antibody-drug conjugates / Amrita Kamath -- Path to market approval : regulatory perspective of ADC nonclinical safety assessments / Stacey Ricci and Natalie Simpson -- Antibody drug conjugates : clinical strategies and applications / Heather E. Vezina, Lucy Lee, Brian J. Schmidt, Manish Gupta -- Antibody-drug conjugates (ADCs) in clinical development / Patricia LoRusso and Joseph McLaughlin -- ADCs approved for use : Trastuzumab emtansine (Kadcyla, T-DM1) in patients with previously treated HER2-positive metastatic breast cancer / Gail Lewis Phillips, Sanne de Hass, Sandhya Girish, and Ellie Guardino -- ADCs approved for use : Brentuximab Vedotin / Sven DeVos and Monica Mead -- Radioimmunotherapy / Jeffrey Wong and Savita Dandapani -- Radiolabeled antibody-based imaging in clinical oncology / Bart Hendriks and Daniel Gaddy -- Antibody-drug conjugates : the next evolution in the cure for cancer -- William C. Olson and Amy Q. Han.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Source of description	Description based on print version record and CIP data provided by publisher.
Issued in other form	Print version: Hoboken, New Jersey : John Wiley & Sons, Inc., [2017] 9781119060680
Genre/form	Electronic books.
LCCN	2016034128
ISBN	9781119060840 (pdf)
ISBN	9781119060802 (epub)

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Antibody-drug conjugates fundamentals, drug development, and clinical outcomes to target cancer / edited by Kenneth J. Olivier Jr., Sara A. Hurvitz.

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