Biodiversity new leads for the pharmaceutical and agrochemical industries / edited by Stephen K. Wrigley ... [et al.].
| Author/creator | International Meeting Biodiversity: A Source of New Leads for the Pharmaceutical and Agrochemical Industries |
| Other author | Wrigley, Stephen. |
| Other author | Royal Society of Chemistry (Great Britain). Biotechnology Group. |
| Other author | Royal Society of Chemistry (Great Britain) |
| Format | Electronic |
| Publication Info | Cambridge, UK : Royal Society of Chemistry, [2000] |
| Description | 313 pages : illustrations ; 24 cm |
| Supplemental Content | Full text available from Ebook Central - Academic Complete |
| Subjects |
| Series | Special publication ; no. 257 Special publication (Royal Society of Chemistry (Great Britain)) ; no. 257. ^A102120 |
| Contents | Microbial natural products : a past with a future / A.L. Demain -- New concepts and approaches to biodiversity / D.F. Marshall and J.R. Hillman -- Natural products drug discovery at the National Cancer Institute : past achievements and new directions for the new millennium / G.M. Cragg, M.R. Boyd, Y.F. Hallock, D.J. Newman, E.A. Sausville and M.K. Wolpert -- Secondary metabolites as a vital source of animal health products / J.C. Ruddock -- The relationship between natural products and synthetic chemistry in the discovery process / S. Brewer -- Natural products vs. combinatorials : a case study / D. Baker, U. Mocek and C. Garr -- Mushrooms, microbes and medicines / A. Buss and M.A. Hayes -- Signal transduction inhibitors from microorganisms / S.K. Wrigley, D.A. Kau, B. Waters and J.E. Davies -- Novel inhibitors of lipoprotein associated phospholipase A2 produced by Pseudomonas fluorescens DSM 11579 / J. Thirkettle -- Marine organisms as a source of novel lead structures for drug development / A.E. Wright -- The anticancer dolastatins as cyanobacterial metabolites / G.G. Harrigan, H. Luesch, R.E. Moore and V.J. Paul -- A Cu2+ selective marine metabolite / L.A. Morris and M. Jaspars -- Water soluble bioactive alkaloids / A.A. Watson and R.J. Nash -- 'Lessons from nature' : can ecology provide new leads in the search for novel bioactive chemicals from tropical rainforests? / P. Reddell and V. Gordon -- Brazilian biodiversity : a source of phytomedicines, natural drugs and leads for the pharmaceutical and agrochemical industries / B. Gilbert -- A modern perspective to the traditional use of plants in the Highlands of Scotland / R. Constadouros -- In vivo and in vitro biosynthetic studies : understanding and exploiting natural pathways / T.J. Simpson -- Fused ring aromatic polyketides are formed by different cyclisation pathways in fungi and streptomycetes / R. Thomas -- The strobilurin fungicides--from mushroom to molecule to market / J.M. Clough -- A synthesis of (+)-Prelog-Djerassi lactonic acid / S.D. Hiscock, P.B. Hitchcock and P.J. Parsons -- N-([alpha]-aminoacyl)-5ʹ-O-sulfamoyladenosines : natural product based inhibitors of amino acyl tRNA synthetases / K. Beautemont, E.J.T. Chrystal, J. Howard and S.M. Ridley. |
| Summary | "The continuing quest for new drugs and agrochemicals has seen researchers looking to the natural world for potential products. Plants and microorganisms have long been investigated as sources of new lead compounds, but the scope of this book has been widened to include substances derived from marine organisms. Advances in genetic engineering, high throughput screening and structure elucidation have also opened up further avenues for exploration. Competitive pressure from the field of combinatorial chemistry has expedited new approaches to natural product analysis and stimulated debate on the industrial utilization of natural products. Biodiversity: New Leads for the Pharmaceutical and Agrochemical Industries reviews and discusses aspects of modern natural products research. The central theme of many articles is the sustainable use of global biodiversity. Microbial, plant and marine products are presented as the sources of new drugs, including antifungal products, antibiotics, anticancer agents and animal health products. There is also coverage of the biosynthesis of polyketides and the chemical synthesis of natural products and their derivatives"--Page 4 of cover. |
| General note | "The proceedings of the International Meeting Biodiversity: A Source of New Leads for the Pharmaceutical and Agrochemical Industries held on 5-8 September 1999 at the University of St Andrews"--Title page verso. |
| General note | Conference organized by the Biotechnology Group of the Industrial Division of The Royal Society of Chemistry. |
| Bibliography note | Includes bibliographical references and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| LCCN | 2014432643 |
| ISBN | 0854048308 |
| ISBN | 9780854048304 |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |