The future of HIV-1 therapeutics : resistance is futile? / Bruce E. Torbett, David S. Goodsell, Douglas D. Richman, editors.
| Other author | Torbett, Bruce E. (Bruce Edward), editor. |
| Other author | Goodsell, David S., editor. |
| Other author | Richman, Douglas D., editor. |
| Format | Electronic |
| Publication | London : Springer, 2015. |
| Description | 1 online resource : color illustrations. |
| Supplemental Content | ProQuest Ebook Central |
| Subjects |
| Series | Current topics in microbiology and immunology ; volume 389 Current topics in microbiology and immunology ; 389. ^A654827 |
| Contents | HIV Therapy--Looking Towards the Future -- Computational challenges of structure-based approaches applied to HIV -- Nucleocapsid Protein: A Desirable Target For Future Therapies Against HIV-1 -- HIV-1 integrase multimerization as a therapeutic target -- Targeting HIV transcription: The quest for a functional cure -- Targeting the HIV RNA Genome: High-Hanging Fruit Only Needs a Longer Ladder -- HIV-1 Gag: An Emerging Target for Antiretroviral Therapy -- The Triple Threat of HIV-1 Protease Inhibitors -- Illustrations of the HIV Life Cycle. |
| Abstract | This volume thoroughly covers HIV-1 antiretrovirals currently in clinical use, together with their advantages and limitations. HIV-1 inhibitor resistance is discussed in detail, and critical assessments as to what will be required of future antiretrovirals in order to halt viral replication, reduce viral resistance, and alter the state of viral latency are presented. Experts at the forefront of HIV-1 research provide overviews of approaches from the fields of virology, chemical biology and structural biology for obtaining small molecule inhibitors that target viral regulatory and structural components at multiple points in the viral lifecycle. The individual chapters will appeal to scientists and clinicians alike. |
| Bibliography note | Includes bibliographical references and index. |
| Source of description | Vendor-supplied metadata. |
| Issued in other form | Print version: Future of HIV-1 therapeutics. Cham : Springer, [2015] 9783319185170 |
| Genre/form | Electronic books. |
| Genre/form | Electronic books. |
| ISBN | 9783319185187 (electronic bk.) |
| ISBN | 3319185187 (electronic bk.) |
| ISBN | 3319185179 |
| ISBN | 9783319185170 |
| Standard identifier# | 10.1007/978-3-319-18518-7 |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |