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003 OCoLC;

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007 cr unu||||||||;

008 210914s2021 ncua obm 000 0 eng d;

035 a| (Sirsi) o1268150288;

035 a| (OCoLC)1268150288;

049 a| EREE;

090 a| QC793.5.E627;

100 1 a| Hawkins, Wilson L.,e| author.?| UNAUTHORIZED;

245 10 a| Electron emission from fast proton and carbon ion interactions with gold nanoparticles and amorphous solid water /c| by Wilson Hawkins.;

264 1 a| [Greenville, N.C.] :b| [East Carolina University],c| 2021.;

300 a| 1 online resource (149 pages) :b| color illustrations;

336 a| textb| txt2| rdacontent;

337 a| computerb| c2| rdamedia;

338 a| online resourceb| cr2| rdacarrier;

347 a| text file;

347 b| PDF;

347 c| 17.59 MB;

538 a| System requirements: Adobe Reader.;

538 a| Mode of access: World Wide Web.;

502 b| Ph. D.c| East Carolina Universityd| 2021;

500 a| Presented to the faculty of the Department of Physics;

500 a| Advisor: Jefferson Shinpaugh;

500 a| Title from PDF t.p. (viewed August 31, 2022).;

520 3 a| Widely used in the treatment of cancer, radiation therapy delivers a lethal dose of energy to malignant tissue. Modeling the deposition of energy in the interactions of the radiation with biological material is important to accurately predict the dosimetry and the subsequent biological outcomes. Recently, nanoparticles have been observed to increase the effective damage during radiation therapy. In this study, charged particle interactions with biological materials were studied to model energy deposition and electron transport, as well as a comparison study of fast ion interactions with gold nanoparticles acting as radiosensitizers. Electron emission from metal and hydrated metal surfaces was measured for irradiation by protons and carbon ions in an energy range of maximum energy deposition, 1 to 6 MeV (near the so-called Bragg peak). Doubly differential electron emission yields were measured under ultra-high vacuum conditions using the spectroscopic technique time-of-flight analysis for low-energy electrons. This study included targets that are relevant for biological modeling, such as amorphous solid water, as well as for nanoparticle radiosensitizers, such as gold nanostructures, for which surface plasmon resonances have been proposed to contribute to the secondary electron emission.;

504 a| Includes bibliographical references.;

650 0 a| Electronsx| Emission.=| ^A283789;

650 0 a| Nanoparticles.=| ^A210009;

650 0 a| Gold.=| ^A18782;

653 a| Proton;

653 a| Carbon;

655 7 a| Academic theses.2| fast0| (OCoLC)fst01726453;

655 7 a| Academic theses.2| lcgft;

655 7 a| Thèses et écrits académiques.2| rvmgf0| (CaQQLa)RVMGF-000001173;

655 2 a| Academic Dissertation.0| (DNLM)D019478?| UNAUTHORIZED;

700 1 a| Shinpaugh, Jefferson L.,e| degree supervisor.?| UNAUTHORIZED;

710 2 a| East Carolina University.b| Department of Physics.?| UNAUTHORIZED;

856 40 u| http://hdl.handle.net/10342/9389z| Access via ScholarShip;

949 o| wjh;

994 a| C0b| ERE;

596 a| 1 4;

998 a| 5668833;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 5668833-1001l| JNETm| JOYNERr| Ys| Yt| JNE3ETDu| 9/14/2021x| ETDz| JERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 5668833-2001l| HSLELECm| HSLr| Ys| Yt| HEETDu| 9/14/2021x| ETDz| HERESOURCE;

Electron emission from fast proton and carbon ion interactions with gold nanoparticles and amorphous solid water / by Wilson Hawkins.

Author/creator	Hawkins, Wilson L. author.
Other author	Shinpaugh, Jefferson L., degree supervisor.
Other author	East Carolina University. Department of Physics.
Format	Theses and dissertations
Publication	[Greenville, N.C.] : [East Carolina University], 2021.
Description	1 online resource (149 pages) : color illustrations
Supplemental Content	Access via ScholarShip
Subjects	Electrons--Emission. Nanoparticles. Gold.

Summary	Widely used in the treatment of cancer, radiation therapy delivers a lethal dose of energy to malignant tissue. Modeling the deposition of energy in the interactions of the radiation with biological material is important to accurately predict the dosimetry and the subsequent biological outcomes. Recently, nanoparticles have been observed to increase the effective damage during radiation therapy. In this study, charged particle interactions with biological materials were studied to model energy deposition and electron transport, as well as a comparison study of fast ion interactions with gold nanoparticles acting as radiosensitizers. Electron emission from metal and hydrated metal surfaces was measured for irradiation by protons and carbon ions in an energy range of maximum energy deposition, 1 to 6 MeV (near the so-called Bragg peak). Doubly differential electron emission yields were measured under ultra-high vacuum conditions using the spectroscopic technique time-of-flight analysis for low-energy electrons. This study included targets that are relevant for biological modeling, such as amorphous solid water, as well as for nanoparticle radiosensitizers, such as gold nanostructures, for which surface plasmon resonances have been proposed to contribute to the secondary electron emission.
General note	Presented to the faculty of the Department of Physics
General note	Advisor: Jefferson Shinpaugh
General note	Title from PDF t.p. (viewed August 31, 2022).
Dissertation note	Ph. D. East Carolina University 2021
Bibliography note	Includes bibliographical references.
Technical details	System requirements: Adobe Reader.
Technical details	Mode of access: World Wide Web.
Genre/form	Academic theses.
Genre/form	Academic theses.
Genre/form	Thèses et écrits académiques.

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Electron emission from fast proton and carbon ion interactions with gold nanoparticles and amorphous solid water / by Wilson Hawkins.

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