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245 00 a| DNA methylation and cancer therapyh| [electronic resource] /c| [edited by] Moshe Szyf.;

260 a| Georgetown, Tex. :b| Landes Bioscience/Eurekah.com ;a| New York, N.Y. :b| Kluwer Academic/Plenum,;

300 a| 239 p. :b| ill.;

490 1 a| Medical intelligence unit;

504 a| Includes bibliographical references and index.;

505 0 a| DNA methylation: three decades in search of function / Aharon Razin -- Epigenetic mechanisms of gene regulation: relationships between DNA methylation, histone modification, and chromatin structure / Keith D. Robertson -- DNA hypo- vs. hypermethylation in cancer: tumor specificity, tumor progression, and therapeutic implications / Melanie Ehrlich and Guanchao Jiang -- DNA methylation in urological cancers / Wolfgang A. Schulz and Hans-Helge Seifert -- DNA methylation in colorectal cancer / Jeremy R. Jass ... [et al.] -- CpG island hypermethylation of tumor suppressor genes in human cancer: concepts, methodologies and uses / Michel Herranz and Manel Esteller -- The loss of methyl groups in DNA of tumor cells and tissues: the immunochemical approach / Alain Niveleau ... [et al.] -- Identifying clinicopathological association of DNA hypermethylation in cancers using CpG island microarrays / Susan H. Wei ... [et al.] -- Methylation analysis in cancer: (epi)genomic fast track from discovery to clinical routine / Carolina Haefliger, Sabine Maier and Alexander Olek --;

505 0 a| Regulation of DNA methyltransferases in cancer / Nancy Detich and Moshe Szyf -- Inhibition of poly(ADP-ribosyl)ation allows DNA hypermethylation / Anna Reale ... [et al.] -- The role of active demethylation in cancer and its therapeutic potential / Moshe Szyf ... [et al.] -- Purine analogues and their role in methylation and cancer chemotherapy / Katherine L. Seley and Sylvester L. Mosley -- DNA methyltransferase inhibitors: paving the way for epigenetic cancer therapeutics / Gregory K. Reid and A. Robert MacLeod -- Preclinical and clinical studies on 5-aza-2'-deoxycytidine, a potent inhibitor of DNA methylation, in cancer therapy / Richard L. Momparler -- Anticancer gene therapy by in vivo DNA electrotransfer of MBD2 antisense / Pascal Bigey and Daniel Scherman.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 12 a| Neoplasmsx| genetics=| ^A920613;

650 22 a| Neoplasmsx| therapy=| ^A918606;

650 22 a| DNA Methylation=| ^A930381;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Szyf, Moshe.=| ^A872137;

830 0 a| Medical intelligence unit (Unnumbered : 2003)=| ^A676181;

856 40 z| Full text available from eBooks on EBSCOhostu| https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=125907&scope=site&custid=s5822723&authtype=ip,shib;

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DNA methylation and cancer therapy / [edited by] Moshe Szyf.

Other author	Szyf, Moshe.
Format	Electronic
Publication Info	Georgetown, Tex. : Landes Bioscience/Eurekah.com ; New York, N.Y. : Kluwer Academic/Plenum,
Description	239 p. : ill.
Supplemental Content	Full text available from eBooks on EBSCOhost
Subjects	Neoplasms--genetics. Neoplasms--therapy. DNA Methylation

Series	Medical intelligence unit Medical intelligence unit (Unnumbered : 2003) ^A676181
Contents	DNA methylation: three decades in search of function / Aharon Razin -- Epigenetic mechanisms of gene regulation: relationships between DNA methylation, histone modification, and chromatin structure / Keith D. Robertson -- DNA hypo- vs. hypermethylation in cancer: tumor specificity, tumor progression, and therapeutic implications / Melanie Ehrlich and Guanchao Jiang -- DNA methylation in urological cancers / Wolfgang A. Schulz and Hans-Helge Seifert -- DNA methylation in colorectal cancer / Jeremy R. Jass ... [et al.] -- CpG island hypermethylation of tumor suppressor genes in human cancer: concepts, methodologies and uses / Michel Herranz and Manel Esteller -- The loss of methyl groups in DNA of tumor cells and tissues: the immunochemical approach / Alain Niveleau ... [et al.] -- Identifying clinicopathological association of DNA hypermethylation in cancers using CpG island microarrays / Susan H. Wei ... [et al.] -- Methylation analysis in cancer: (epi)genomic fast track from discovery to clinical routine / Carolina Haefliger, Sabine Maier and Alexander Olek --
Contents	Regulation of DNA methyltransferases in cancer / Nancy Detich and Moshe Szyf -- Inhibition of poly(ADP-ribosyl)ation allows DNA hypermethylation / Anna Reale ... [et al.] -- The role of active demethylation in cancer and its therapeutic potential / Moshe Szyf ... [et al.] -- Purine analogues and their role in methylation and cancer chemotherapy / Katherine L. Seley and Sylvester L. Mosley -- DNA methyltransferase inhibitors: paving the way for epigenetic cancer therapeutics / Gregory K. Reid and A. Robert MacLeod -- Preclinical and clinical studies on 5-aza-2'-deoxycytidine, a potent inhibitor of DNA methylation, in cancer therapy / Richard L. Momparler -- Anticancer gene therapy by in vivo DNA electrotransfer of MBD2 antisense / Pascal Bigey and Daniel Scherman.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2004022708
ISBN	9780306478482
ISBN	030647848X

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DNA methylation and cancer therapy / [edited by] Moshe Szyf.

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