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016 7 a| 0133874822| Uk;

016 7 a| 0134580932| Uk;

016 a| B06006762| bccb;

020 a| 1402037635 (hbk.);

020 a| 9781402037634 (hbk.);

020 a| 1402037643 (ebook);

020 a| 9781402037641 (ebook);

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245 00 a| Genome instability in cancer developmenth| [electronic resource] /c| edited by Erich A. Nigg.;

260 a| New York :b| Springer,;

300 a| xv, 511 p. :b| ill. (some col.) ;c| 26 cm.;

440 0 a| Advances in experimental medicine and biology ;v| v. 570;

504 a| Includes bibliographical references and index.;

505 0 a| The problem of genome instability. The multiplicity of mutations in human cancers / Ranga N. Venkatesan and Lawrence A. Loeb. Monitoring chromosome rearrangements / Michael R. Speicher -- DNA repair and mutagenesis. Nucleotide excision repair and its connection with cancer and ageing / Jaan-Olle Andressoo, Jan H.J. Hoeijmakers and Harm de Waard. DNA mismatch repair and colon cancer / Giancarlo Marra and Josef Jiricny. Base excision repair / Lisiane B. Meira, Nicholas E. Burgis and Leona D. Samson. Genomic instability in cancer development / Penny A. Jeggo. Translesion synthesis and error-prone polymerases / Catherine M. Green and Alan R. Lehmann -- Cell cycle progression and chromosome aberration. The INK4A/ARF network-cell cycle checkpoint or emergency brake? / Ana Gutierrez del Arroyo and Gordon Peters. DNA replication and genomic instability / Wenge Zhu, Tarek Abbas and Anindya Dutta. The dream of every chromosome: equal segregation for a healthy life of the host / Tomohiro Matsumoto and Mitsuhiro Yanagida. Telomere structural dynamics in genome integrity control and carcinogenesis / Roger A. Greenberg and K. Lenhard Rudolph. Gene amplification mechanisms / Michelle Debatisse and Bernard Malfoy. DNA methylation and cancer-associated genetic instability / Melanie Ehrlich. Deregulation of the centrosome cycle and the origin of chromosomal instability in cancer / Wilma L. Lingle, Kara Lukaswiewicz and Jeffrey L. Salisbury -- Genome integrity checkpoints. Mammalian DNA damage response pathway / Zhenkun Lou and Junjie Chen. ATM and cellular response to DNA damage / Martin F. Lavin ... [et al.] Mitotic checkpoint, aneuploidy and cancer / Tim J. Yen and Gary D. Kao.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Cancerx| Genetic aspects.=| ^A6215;

650 0 a| Genomics.=| ^A528942;

650 12 a| Neoplasmsx| genetics.=| ^A920613;

650 12 a| Neoplasmsx| etiology.=| ^A917753;

650 22 a| Genomic Instability.=| ^A941562;

650 22 a| Mutation.=| ^A917789;

650 22 a| DNA Repair.=| ^A923057;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Nigg, Erich A.=| ^A869740;

856 40 z| Full text available from eBooks on EBSCOhostu| https://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&AN=150899&scope=site&custid=s5822723&authtype=ip,shib;

947 a| (OCoLC)ocm63394908;

949 a| CLICK ON WEB ADDRESSw| ASISh| JOYNER188;

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596 a| 1 3 4;

998 a| 5687642;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 5687642-1001l| JNETm| JOYNERr| Ys| Yt| JNESSBKu| 9/18/2021x| EBOOKz| JERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 5687642-2001l| HSLELECm| HSLr| Ys| Yt| HEBKu| 9/18/2021x| EBOOKz| HERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 5687642-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 9/18/2021x| EBOOKz| JERESOURCE;

Genome instability in cancer development / edited by Erich A. Nigg.

Other author	Nigg, Erich A.
Format	Electronic
Publication Info	New York : Springer,
Description	xv, 511 p. : ill. (some col.) ; 26 cm.
Supplemental Content	Full text available from eBooks on EBSCOhost
Subjects	Cancer--Genetic aspects. Genomics. Neoplasms--genetics. Neoplasms--etiology. Genomic Instability. Mutation. DNA Repair.

Series	Advances in experimental medicine and biology ; v. 570
Contents	The problem of genome instability. The multiplicity of mutations in human cancers / Ranga N. Venkatesan and Lawrence A. Loeb. Monitoring chromosome rearrangements / Michael R. Speicher -- DNA repair and mutagenesis. Nucleotide excision repair and its connection with cancer and ageing / Jaan-Olle Andressoo, Jan H.J. Hoeijmakers and Harm de Waard. DNA mismatch repair and colon cancer / Giancarlo Marra and Josef Jiricny. Base excision repair / Lisiane B. Meira, Nicholas E. Burgis and Leona D. Samson. Genomic instability in cancer development / Penny A. Jeggo. Translesion synthesis and error-prone polymerases / Catherine M. Green and Alan R. Lehmann -- Cell cycle progression and chromosome aberration. The INK4A/ARF network-cell cycle checkpoint or emergency brake? / Ana Gutierrez del Arroyo and Gordon Peters. DNA replication and genomic instability / Wenge Zhu, Tarek Abbas and Anindya Dutta. The dream of every chromosome: equal segregation for a healthy life of the host / Tomohiro Matsumoto and Mitsuhiro Yanagida. Telomere structural dynamics in genome integrity control and carcinogenesis / Roger A. Greenberg and K. Lenhard Rudolph. Gene amplification mechanisms / Michelle Debatisse and Bernard Malfoy. DNA methylation and cancer-associated genetic instability / Melanie Ehrlich. Deregulation of the centrosome cycle and the origin of chromosomal instability in cancer / Wilma L. Lingle, Kara Lukaswiewicz and Jeffrey L. Salisbury -- Genome integrity checkpoints. Mammalian DNA damage response pathway / Zhenkun Lou and Junjie Chen. ATM and cellular response to DNA damage / Martin F. Lavin ... [et al.] Mitotic checkpoint, aneuploidy and cancer / Tim J. Yen and Gary D. Kao.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2007275129
ISBN	1402037635 (hbk.)
ISBN	9781402037634 (hbk.)
ISBN	1402037643 (ebook)
ISBN	9781402037641 (ebook)

Genome instability in cancer development / edited by Erich A. Nigg.

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