Small molecule drug discovery methods, molecules and applications / [edited by] Andrea Trabocchi, Elena Lenci.
| Other author | Trabocchi, Andrea. |
| Other author | Lenci, Elena. |
| Format | Electronic |
| Publication Info | Amsterdam, Netherlands ; Cambridge, MA : Elsevier, [2020] |
| Description | xxiii, 332 pages : illustrations (some color) ; 24 cm |
| Supplemental Content | Full text available from eBook - Chemistry 2020 [EBCC20] |
| Subjects |
| Contents | 1 Synthetic approaches toward small molecule libraries -- 2 Chemical reactions for building small molecules -- 3 Chemoinformatics approaches to assess chemical diversity and complexity of small molecules -- 4 Virtual screening of small-molecule libraries -- 5 Screening and biophysics in small molecule discovery -- 6 Principles and applications of small molecule peptidomimetics -- 7 sp2-Iminosugars as chemical mimics for glycodrug design -- 8 Synthesis and biological properties of spiroacetal-containing small molecules -- 9 Centrocountins--synthesis and chemical biology of nature inspired indoloquinolizines -- 10 PPIs as therapeutic targets for anticancer drug discovery: the case study of MDM2 and BET bromodomain inhibitors -- 11 Discovery of small molecules for the treatment of Alzheimer's disease |
| Bibliography note | Includes bibliographical references and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Issued in other form | Electronic version: Small Molecule Drug Discovery. Amsterdam, Netherlands ; Cambridge, MA : Elsevier, [2020] 0128183500 |
| Genre/form | Electronic books. |
| LCCN | 2019956293 |
| ISBN | 9780128183496 (paperback) |
| ISBN | 0128183497 (paperback) |