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245 00 a| Clinical genome sequencingh| [electronic resource] :b| psychological considerations /c| edited by Aad Tibben, Barbara B. Biesecker.;

260 a| London, UK :b| Academic Press,c| [2019];

300 a| xii, 245 pages :b| illustrations ;c| 24 cm;

504 a| Includes bibliographical references and index.;

505 0 a| Genetic Testing Expanded / Aad Tibben, Barbara B. Biesecker -- Genome Sequencing and Individual Responses to Results / Leslie G. Biesecker, Barbara B. Biesecker -- Consenting Patients to Genome Sequencing -- Emilia Niemiec, Heidi Carmen Howard -- Judgment and Decision Making in Genome Sequencing / William M.P. Klein, Barbara B. Biesecker, Erin Turbitt -- Uncertainties in Genome Sequencing / Barbara B. Biesecker, Aad Tibben, Joel Vos -- Direct-to-Consumer Genetic Testing / A. Cecile J.W. Janssens -- Assessing the Psychological Impact of Next-Generation Sequencing Information in the Clinic: An Attempt to Map Terra Incognita? / Marc S. Williams -- Genetic Counseling and Genomic Sequencing / Barbara A. Bernhardt -- Genome Sequencing in Pediatrics: Ethical Issues / Candice Cornelis, Roel H.P. Wouters -- Genome Sequencing in Prenatal Testing and Screening: Lessons Learned From Broadening the Scope of Prenatal Genetics From Conventional Karyotyping to Whole-Genome Microarray Analysis / Sam Riedijk, Karin Diderich, Robert-Jan Galjaard, Gosia Srebniak -- Clinical Genetic Testing and Counseling in Psychiatry / Christian G. Bouwkamp, Zaid Afawi, Steven A. Kushner -- Opportunistic Genomic Screening: Ethical Exploration / Guido de Wert, Wybo Dondorp -- Summary of Key Areas for Research / Barbara B. Biesecker, Aad Tibben;

506 a| Available only to authorized users.;

520 a| Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine.;

538 a| Mode of access: World Wide Web;

650 0 a| Human gene mapping.=| ^A358997;

650 0 a| Human gene mappingx| Moral and ethical aspects.=| ^A358997;

650 12 a| Whole Genome Sequencingx| ethics.?| UNAUTHORIZED;

650 22 a| Precision Medicinex| psychology.=| ^A1018099;

650 22 a| Precision Medicinex| ethics.=| ^A1018099;

650 22 a| Genetic Servicesx| ethics.=| ^A1326622;

650 7 a| Human gene mapping.2| fast0| (OCoLC)fst00963066;

650 7 a| Human gene mappingx| Moral and ethical aspects.2| fast0| (OCoLC)fst00963071;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Tibben, Aad.?| UNAUTHORIZED;

700 1 a| Biesecker, Barbara.?| UNAUTHORIZED;

856 40 z| Full text available from eBook - Biochemistry, Genetics and Molecular Biology 2019u| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbook%2F9780128133354;

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Clinical genome sequencing psychological considerations / edited by Aad Tibben, Barbara B. Biesecker.

Other author	Tibben, Aad.
Other author	Biesecker, Barbara.
Format	Electronic
Publication Info	London, UK : Academic Press, [2019]
Description	xii, 245 pages : illustrations ; 24 cm
Supplemental Content	Full text available from eBook - Biochemistry, Genetics and Molecular Biology 2019
Subjects	Human gene mapping. Human gene mapping--Moral and ethical aspects. Whole Genome Sequencing--ethics. Precision Medicine--psychology. Precision Medicine--ethics. Genetic Services--ethics.

Contents	Genetic Testing Expanded / Aad Tibben, Barbara B. Biesecker -- Genome Sequencing and Individual Responses to Results / Leslie G. Biesecker, Barbara B. Biesecker -- Consenting Patients to Genome Sequencing -- Emilia Niemiec, Heidi Carmen Howard -- Judgment and Decision Making in Genome Sequencing / William M.P. Klein, Barbara B. Biesecker, Erin Turbitt -- Uncertainties in Genome Sequencing / Barbara B. Biesecker, Aad Tibben, Joel Vos -- Direct-to-Consumer Genetic Testing / A. Cecile J.W. Janssens -- Assessing the Psychological Impact of Next-Generation Sequencing Information in the Clinic: An Attempt to Map Terra Incognita? / Marc S. Williams -- Genetic Counseling and Genomic Sequencing / Barbara A. Bernhardt -- Genome Sequencing in Pediatrics: Ethical Issues / Candice Cornelis, Roel H.P. Wouters -- Genome Sequencing in Prenatal Testing and Screening: Lessons Learned From Broadening the Scope of Prenatal Genetics From Conventional Karyotyping to Whole-Genome Microarray Analysis / Sam Riedijk, Karin Diderich, Robert-Jan Galjaard, Gosia Srebniak -- Clinical Genetic Testing and Counseling in Psychiatry / Christian G. Bouwkamp, Zaid Afawi, Steven A. Kushner -- Opportunistic Genomic Screening: Ethical Exploration / Guido de Wert, Wybo Dondorp -- Summary of Key Areas for Research / Barbara B. Biesecker, Aad Tibben
Abstract	Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2019938477
ISBN	9780128133354 (paperback)
ISBN	012813335X (paperback)

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