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010 a| 2021277559;

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016 7 a| 0195461422| Uk;

020 a| 9781785483080q| hardcover;

020 a| 1785483080q| hardcover;

035 a| (WaSeSS)ssj0002500474;

042 a| lccopycat;

049 a| EREEa| NEHH;

050 00 a| QR185.2b| .I56 2019;

060 4 a| QW 541;

082 04 a| 571.962| 23;

100 1 a| Carton, Yves.?| UNAUTHORIZED;

245 10 a| Innate immunityh| [electronic resource] :b| from Louis Pasteur to Jules Hoffmann /c| Yves Carton.;

300 a| xiv, 309 pages :b| illustrations ;c| 24 cm;

504 a| Includes bibliographical references and index.;

505 00 a| Machine generated contents note:g| ch. 1t| Louis Pasteur and Silkworm Disease (1865 -- 1870) --g| 1.1.t| Introduction --g| 1.2.t| Current knowledge about silkworms and pebrine disease --g| 1.3.t| A disaster announced in France for silkworm farms --g| 1.4.t| Knowledge acquired on pebrine in the 19th Century --g| 1.5.t| Louis Pasteur's work on pebrine --g| 1.5.1.t| Louis Pasteur's career before 1865 --g| 1.5.2.t| 1865: the discovery of pepper disease (pebrine) --g| 1.5.3.t| 1866: what problems to solve? --g| 1.5.4.t| 1867: the first results obtained on pebrine --g| 1.5.5.t| 1868: industrial egg laying and flacherie disease --g| 1.5.6.t| 1869: having his method approved by rearers --g| 1.5.7.t| 1870: Villa Vicentina in Italy --g| 1.6.t| Conclusion --g| ch. 2t| Ilya Metchnikov at the Pasteur Institute (1886 -- 1916) --g| 2.1.t| Introduction --g| 2.2.t| Ilya Metchnikov's biography --g| 2.3.t| The discovery of phagocytosis, the basis of immunity, in Messina --g| 2.4.t| Search for a phagocytic function in vivo --g| 2.5.t| Metchnikov in search of a place of freedom to conduct his work --g| 2.6.t| 1887: a meeting with Louis Pasteur --g| 2.7.t| Metchnikov at the Pasteur Institute: affirming his conceptions --g| 2.8.t| Metchnikov, a quality teacher-researcher: steps towards the Nobel Prize (1908) --g| 2.9.t| Conclusion --g| ch. 3t| The Post-Metchnikov Era at the Pasteur Institute (1920 -- 1940) --g| 3.1.t| Introduction --g| 3.2.t| The researchers trained by I. Metchnikov --g| 3.2.1.t| Alexandre Besredka, Metchnikov's official successor --g| 3.2.2.t| Jules Bordet (1870 -- 1961) Nobel Prize 1919 --g| 3.2.3.t| Jean Cantacuzene (1863 -- 1934), the Franco-Romanian student --g| 3.2.4.t| Felix Mesnil (1868 -- 1938), Head of Department at the Pasteur Institute --g| 3.3.t| Creation of a group on Insect immunity --g| 3.3.1.t| Serguei Metalnikov (1870 -- 1946): his scientific career before 1918 --g| 3.3.2.t| S. Metalnikov's work on Insects --g| 3.3.3.t| S. Metalnikov's collaborators --g| 3.4.t| Conclusion --g| ch. 4t| Andre Paillot against the "Phagocytic" Dogma: Humoral Immunity --g| 4.1.t| Introduction --g| 4.2.t| Precursors --g| 4.2.1.t| Felix D'herelle --g| 4.2.2.t| Rudolph W. Glaser in the United States --g| 4.3.t| Andre Paillot (1885 -- 1944), the rebel --g| 4.3.1.t| His biography --g| 4.3.2.t| Andre Paillot's work on the humoral immunity of Insects --g| 4.4.t| "Continuers" --g| 4.4.1.t| The work of Vladimir Zernoff --g| 4.4.2.t| The work of Andre Charles Holland in Nancy --g| 4.4.3.t| The work of Emile Couvreur in Lyon --g| 4.5.t| Conclusion --g| ch. 5t| The Crossing of the Desert for Invertebrate Immunity (1960 -- 1990) --g| 5.1.t| Introduction --g| 5.2.t| The humoral immunity of Insects in North America --g| 5.3.t| Research in France on the innate immunity of Insects --g| 5.3.1.t| The comparative pathology laboratory (Saint-Christol-les-Ales) --g| 5.3.2.t| The biological control laboratory at the Pasteur Institute --g| 5.3.3.t| The CNRS Evolutionary Biology Laboratory (Gif-sur-Yvette) --g| 5.4.t| Transplantation: the "door opener" expected by Invertebrate immunologists --g| 5.5.t| Wanting to do well, results discussed and questioned --g| 5.6.t| Conclusion --g| ch. 6t| The Strasbourg Laboratory: Towards the Nobel Prize (2011) --g| 6.1.t| Introduction --g| 6.2.t| The Strasbourg laboratory in the 1960s and 1980s --g| 6.3.t| The recruitment of Jules Hoffmann --g| 6.4.t| The work oriented towards the Insect's molting hormone: ecdysone --g| 6.5.t| Early work on locust immunity --g| 6.6.t| Hans Boman's laboratory, Stockholm University (Sweden) --g| 6.7.t| Establishment of an "Insect Immunity" team in the Strasbourg laboratory --g| 6.8.t| The entire laboratory switch to "all-immunity" --g| 6.8.1.t| Identification of antibacterial factors (AMPs) in Drosophila --g| 6.8.2.t| How are the genes encoding these antimicrobial peptides (AMPs) controlled and expressed? --g| 6.8.3.t| How does the Insect perceive the aggression of the pathogen, and can it discriminate between these different aggressions? --g| 6.9.t| The 2011 Nobel Prize Award recognizing innate immunity --g| 6.10.t| Conclusion.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Natural immunity.=| ^A2992;

650 2 a| Immunity, Innate.=| ^A925515;

650 22 a| History, 19th Century.=| ^A941126;

650 22 a| History, 20th Century.=| ^A941311;

650 22 a| History, 21st Century.=| ^A943886;

650 7 a| Natural immunity.2| fast0| (OCoLC)fst01034361;

655 0 a| Electronic books.=| ^A491897;

856 40 z| Full text available from eBook - Biomedical Science and Medicine 2019u| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbook%2F9781785483080;

947 a| (OCoLC)on1113309674;

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Innate immunity from Louis Pasteur to Jules Hoffmann / Yves Carton.

Author/creator	Carton, Yves
Format	Electronic
Publication Info	London, UK : ISTE Press, Ltd ; Kidlington, Oxford, UK : Elsevier Ltd, 2019.
Description	xiv, 309 pages : illustrations ; 24 cm
Supplemental Content	Full text available from eBook - Biomedical Science and Medicine 2019
Subjects	Natural immunity. Immunity, Innate. History, 19th Century. History, 20th Century. History, 21st Century.

Contents	Machine generated contents note: ch. 1 Louis Pasteur and Silkworm Disease (1865 -- 1870) -- 1.1. Introduction -- 1.2. Current knowledge about silkworms and pebrine disease -- 1.3. A disaster announced in France for silkworm farms -- 1.4. Knowledge acquired on pebrine in the 19th Century -- 1.5. Louis Pasteur's work on pebrine -- 1.5.1. Louis Pasteur's career before 1865 -- 1.5.2. 1865: the discovery of pepper disease (pebrine) -- 1.5.3. 1866: what problems to solve? -- 1.5.4. 1867: the first results obtained on pebrine -- 1.5.5. 1868: industrial egg laying and flacherie disease -- 1.5.6. 1869: having his method approved by rearers -- 1.5.7. 1870: Villa Vicentina in Italy -- 1.6. Conclusion -- ch. 2 Ilya Metchnikov at the Pasteur Institute (1886 -- 1916) -- 2.1. Introduction -- 2.2. Ilya Metchnikov's biography -- 2.3. The discovery of phagocytosis, the basis of immunity, in Messina -- 2.4. Search for a phagocytic function in vivo -- 2.5. Metchnikov in search of a place of freedom to conduct his work -- 2.6. 1887: a meeting with Louis Pasteur -- 2.7. Metchnikov at the Pasteur Institute: affirming his conceptions -- 2.8. Metchnikov, a quality teacher-researcher: steps towards the Nobel Prize (1908) -- 2.9. Conclusion -- ch. 3 The Post-Metchnikov Era at the Pasteur Institute (1920 -- 1940) -- 3.1. Introduction -- 3.2. The researchers trained by I. Metchnikov -- 3.2.1. Alexandre Besredka, Metchnikov's official successor -- 3.2.2. Jules Bordet (1870 -- 1961) Nobel Prize 1919 -- 3.2.3. Jean Cantacuzene (1863 -- 1934), the Franco-Romanian student -- 3.2.4. Felix Mesnil (1868 -- 1938), Head of Department at the Pasteur Institute -- 3.3. Creation of a group on Insect immunity -- 3.3.1. Serguei Metalnikov (1870 -- 1946): his scientific career before 1918 -- 3.3.2. S. Metalnikov's work on Insects -- 3.3.3. S. Metalnikov's collaborators -- 3.4. Conclusion -- ch. 4 Andre Paillot against the "Phagocytic" Dogma: Humoral Immunity -- 4.1. Introduction -- 4.2. Precursors -- 4.2.1. Felix D'herelle -- 4.2.2. Rudolph W. Glaser in the United States -- 4.3. Andre Paillot (1885 -- 1944), the rebel -- 4.3.1. His biography -- 4.3.2. Andre Paillot's work on the humoral immunity of Insects -- 4.4. "Continuers" -- 4.4.1. The work of Vladimir Zernoff -- 4.4.2. The work of Andre Charles Holland in Nancy -- 4.4.3. The work of Emile Couvreur in Lyon -- 4.5. Conclusion -- ch. 5 The Crossing of the Desert for Invertebrate Immunity (1960 -- 1990) -- 5.1. Introduction -- 5.2. The humoral immunity of Insects in North America -- 5.3. Research in France on the innate immunity of Insects -- 5.3.1. The comparative pathology laboratory (Saint-Christol-les-Ales) -- 5.3.2. The biological control laboratory at the Pasteur Institute -- 5.3.3. The CNRS Evolutionary Biology Laboratory (Gif-sur-Yvette) -- 5.4. Transplantation: the "door opener" expected by Invertebrate immunologists -- 5.5. Wanting to do well, results discussed and questioned -- 5.6. Conclusion -- ch. 6 The Strasbourg Laboratory: Towards the Nobel Prize (2011) -- 6.1. Introduction -- 6.2. The Strasbourg laboratory in the 1960s and 1980s -- 6.3. The recruitment of Jules Hoffmann -- 6.4. The work oriented towards the Insect's molting hormone: ecdysone -- 6.5. Early work on locust immunity -- 6.6. Hans Boman's laboratory, Stockholm University (Sweden) -- 6.7. Establishment of an "Insect Immunity" team in the Strasbourg laboratory -- 6.8. The entire laboratory switch to "all-immunity" -- 6.8.1. Identification of antibacterial factors (AMPs) in Drosophila -- 6.8.2. How are the genes encoding these antimicrobial peptides (AMPs) controlled and expressed? -- 6.8.3. How does the Insect perceive the aggression of the pathogen, and can it discriminate between these different aggressions? -- 6.9. The 2011 Nobel Prize Award recognizing innate immunity -- 6.10. Conclusion.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2021277559
ISBN	9781785483080 hardcover
ISBN	1785483080 hardcover

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