Quantitative pharmacology and individualized therapy strategies in development of therapeutic proteins for immune-mediated inflammatory diseases / edited by Honghui Zhou, Janssen Research and Development, LLC, Spring House, PA, Diane R. Mould, Projections Research, Inc., Phoenixville, PA.

Other author Zhou, Honghui.
Other author Mould, Diane R. (Diane Renee), 1960-
Format Electronic
Publication InfoHoboken, NJ : Wiley, 2019.
Descriptionxxviii, 465 pages : illustrations ; 23 cm.
Supplemental ContentFull text available from Ebook Central - Academic Complete
Subjects

Abstract "Focused on quantitative pharmacology and individualized therapy for developing biotherapeutics in immune-mediated inflammatory diseases, this book discusses both theoretical and practical aspects and includes case studies illustrating applications in drug development. Provides frontline knowledge of using PK/PD modeling tools to address a variety of problems in development of therapeutic proteins. Reviews and discusses biomarkers, systems pharmacology, PBPK modeling, and target-mediated modeling, as translational tools. Helps readers understand disease progression and identify of mechanisms-based biomarkers with clinical relevance"--Provided by publisher.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2018051418
ISBN9781119289197 (hardback)
ISBN(PDF)
ISBN(ePub)

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Electronic Resources Access Content Online ✔ Available