RNA-based regulation in human health and disease / edited by Rajesh Pandey.
| Other author | Pandey, Rajesh. |
| Format | Electronic |
| Publication Info | London : Elsevier Academic Press, [2020] |
| Description | xix, 424 pages : illustrations (chiefly color), color charts ; 24 cm |
| Supplemental Content | Full text available from eBook - Biochemistry, Genetics and Molecular Biology 2020 [EBCBGMB20] |
| Subjects |
| Series | Translational epigenetics ; 19 Translational epigenetics series 19. ^A1311478 |
| Contents | Introduction / Rajesh Pandey -- Non-coding RNAs: ever-expanding diversity of types and functions / Subhash Chandra Lakhotia, Bibekanand Mallick and Jyoti Roy -- Functional categories of RNA regulation / Pavithra L. Chavali, Reshma Ramachandran and Sreenivas Chavali -- The dynamic aspects of RNA regulation / Ravi Shankar -- RNA beyond humans / Nar Singh Chauhan, Monika, Tarun Kumar, Pinki Sharma and Khushboo Goyal -- Extracellular RNA in human health and disease / Arijit Mukhopadhyay, Nishtha Bhargava and Sowmya Chinta -- RNA and malaria pathogenesis / Mritunjay Saxena and Gunjan Arora -- RNA and metabolic disorders / Gaurav Verma and Susana González-Rico -- RNA toxicity in tandem nucleotide repeats mediated neurodegenerative disorders / Nishu Tyagi, Uzma Shamim and Mohammed Faruq -- Regulation by non-coding RNAs in respiratory disorders / Ankur Kulshreshtha and Anurag Agrawal -- RNA in cancer / Maciej Ciésla -- RNA and inflammatory autoimmune diseases / Bhawna Gupta, Archana Tripathy and Kumar Sagar Jaiswal -- RNA and bacterial infection / Amitesh Anand and Vijay Soni -- RNA and stress / Janani Srinivasa Vasudevan, Akshay Kanakan, Shweta Sahni and Rajesh Pandey -- RNA and aging / Milan Mus̆o -- Experimental toolkit to study RNA level regulation / Aniket Bhattacharya, Gaura Chaturvedi, Khushboo Singhal and Rajesh Pandey -- Industry perspective / Praveen Gupta and Debjani Saha -- Summary and future perspectives / Rajesh Pandey. |
| Abstract | Rajesh Pandey's lab focuses on Integrative Genomics of Host-Pathogen wherein RNA plays a central role towards modulating pathogenicity. RNA-Based Regulation in Human Health and Disease offers an in-depth exploration of RNA-mediated genome regulation at different hierarchies. Beginning with a multitude of canonical and noncanonical RNA populations, especially noncoding RNA in human physiology and evolution, further sections examine the various classes of RNAs (from small to large noncoding and extracellular RNAs), functional categories of RNA regulation (RNA-binding proteins, alternative splicing, RNA editing, antisense transcripts, and RNA G-quadruplexes), dynamic aspects of RNA regulation modulating physiological homeostasis (aging), role of RNA beyond humans, tools and technologies for RNA research (wet lab and computational), and future prospects for RNA-based diagnostics and therapeutics. One of the core strengths of the book includes spectrum of disease-specific chapters from experts in the field highlighting RNA-based regulation in metabolic and neurodegenerative disorders, cancer, inflammatory disease, viral and bacterial infections. We hope the book helps researchers, students, and clinicians appreciate the role of RNA-based regulation in genome regulation, aiding the development of useful biomarkers for prognosis, diagnosis, and novel RNA-based therapeutics. -- Page 4 of cover. |
| Bibliography note | Includes bibliographical references and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| LCCN | 2020951109 |
| ISBN | 9780128171936 |
| ISBN | 0128171936 |