Biomarkers of Postpartum Psychiatric Disorders.
| Author/creator | Payne, Jennifer L. |
| Other author | Osborne, Lauren M. |
| Format | Electronic |
| Publication Info | San Diego : Elsevier Science & Technology, 2019. |
| Description | 1 online resource (238 pages) |
| Supplemental Content | Direct link to ebook |
| Subjects |
| Contents | Front Cover; BIOMARKERS OF POSTPARTUM PSYCHIATRIC DISORDERS; BIOMARKERS OF POSTPARTUM PSYCHIATRIC DISORDERS; Copyright; Contents; Contributors; Preface; References; 1 -- Clinical phenotypes of peripartum depression and time of onset: the PACT Consortium; Introduction; Rationale and creation of the PACT Consortium; Membership and committees; Approach; Specific research aims of the PACT Consortium; Summary and future directions; References; 2 -- Genetic basis for postpartum depression; Introduction; General approach to genetic studies; Heritability and familial aggregation of PPD |
| Contents | Heritability of PPD versus nonpostpartum MDESPPD and bipolar disorder; Genome-wide linkage and association studies; Candidate gene studies; Moving forward: approaches for identifyng the genetic basis of PPD; Conclusions; References; 3 -- Epigenetic biomarkers of postpartum depression; Introduction; Estrogen-based epigenetic studies in postpartum depression; Oxytocin receptor epigenetic studies of postpartum depression; Conclusions; References; 4 -- Potential hormonal and neurochemical biomarkers for postpartum depression; Introduction; Neuroactive steroid hormones |
| Contents | Progesterone and allopregnanoloneEstrogens; Testosterone; The HPA axis; Thyroid hormones; The monoamines; Serotonin; Epinephrine and norepinephrine; Dopamine; Brain-derived Neurotrophic factor; The microbiome; Conclusions; References; 5 -- Immunological biomarkers of postpartum depression; Introduction; Early work; Interleukin 6; Other cytokines; More complex immune markers and associations; Discussion; References; 6 -- Phenomenology of perinatal obsessive-compulsive disorder; Introduction; Clinical phenomenology; The nature of obsessive-compulsive disorder |
| Contents | Perinatal obsessive-compulsive disorder symptomsComorbidity and differential diagnoses; Postpartum depression; Postpartum psychosis; Prevalence and incidence; Prenatal obsessive-compulsive disorder; Postpartum obsessive-compulsive disorder; Maintaining factors; Normally occurring intrusive thoughts; Situational and cognitive factors; Effects of avoidance and compulsive rituals; Case vignette; Summary and conclusions; References; 7 -- Genetics of perinatal obsessive-compulsive disorder: a focus on past genetic studies to inform future inquiry; Introduction; Family and twin studies |
| Contents | Linkage studiesGenome-wide association studies; Candidate genes; SERT genes; Dopamine receptor and transporter genes; COMT gene; Monoamine oxidase-A gene; Glutamate transporter gene; BDNF gene; Oxytocin receptor; Estrogen receptor genes; Conclusion; References; Further reading; 8 -- Hormonal contributions to perinatal obsessive-compulsive disorder; Introduction; Evidence for contribution by specific hormones; Estrogen; Progesterone; Allopregnanolone; Oxytocin; The hypothalamic-pituitaryadrenal axis and cortisol; Challenges; Future directions; References |
| Contents | 9 -- Immunological biomarkers of postpartum obsessive-compulsive disorder |
| Source of description | Print version record. |
| Issued in other form | Print version: Payne, Jennifer L. Biomarkers of Postpartum Psychiatric Disorders. San Diego : Elsevier Science & Technology, ©2019 9780128155080 |
| ISBN | 9780128158364 |
| ISBN | 0128158360 |