Early identification of perioperative acute kidney injury utilizing novel renal biomarkers / by Angela M. Ciuca.
| Author/creator | Ciuca, Angela M. author. |
| Other author | Bolin, Linda P., degree supervisor. |
| Other author | East Carolina University. College of Nursing. |
| Format | Theses and dissertations |
| Publication | [Greenville, N.C.] : [East Carolina University], 2023. |
| Description | 1 online resource (64 pages) : illustrations (some color) |
| Supplemental Content | Access via ScholarShip |
| Subjects |
| Series | ECU College of Nursing thesis ECU College of Nursing thesis. |
| Summary | Acute kidney injury (AKI) is a complication of major surgery. Novel renal biomarkers have been identified that show good sensitivity for assessing the risk of AKI development much earlier than current diagnostic measures. These biomarkers were primarily studied in a specific cardiac surgical population. The gold standard diagnostic measure of AKI is a change in serum creatinine (SCr), which is a late marker of renal functional loss. The aim of this study is to utilize NephroCheck[registered] urine assay for tissue inhibitor of metalloproteinase-2 and insulin-like growth factor binding protein 7 (uTIMP-2*IGFBP7), two novel renal inflammatory biomarkers, to assess the risk of developing an AKI after major intraabdominal surgery for adult surgical patients. |
| General note | Presented to the Faculty of the Department of Nursing Science |
| General note | Advisor: Linda P. Bolin |
| General note | Title from PDF t.p. (viewed September 9, 2024). |
| Dissertation note | Ph.D. East Carolina University 2023. |
| Bibliography note | Includes bibliographical references. |
| Technical details | System requirements: Adobe Reader. |
| Technical details | Mode of access: World Wide Web. |