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010 a| 2013011177;

020 a| 9780262019699 (hardcover : alk. paper);

020 a| 0262019698 (hardcover : alk. paper);

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245 00 a| Genetic influences on addictionh| [electronic resource] :b| an intermediate phenotype approach /c| edited by James MacKillop and Marcus R. Munafò.;

260 a| Cambridge, Massachusetts :b| The MIT Press,c| [2013];

300 a| x, 386 pages :b| illustrations ;c| 24 cm;

504 a| Includes bibliographical references and index.;

505 0 a| An intermediate phenotype approach to addiction genetics / James MacKillop & Marcus R. Munafò -- Electrophysiological intermediate phenotypes for the detection of genetic influences on alcoholism / Mary-Anne Enoch -- Differential metabolism of alcohol as an intermediate phenotype of risk for alcohol use disorders : alcohol and aldehyde dehydrogenase variants / Tamara L. Wall, Susan Luczak, Daria Orlowska, and Danielle Pandika -- Nicotine metabolism as an intermediate phenotype / Meghan J. Chenoweth & Rachel F. Tyndale -- Subjective responses to alcohol as an endophenotype : implications for alcoholism etiology and treatment development / Lara A. Ray & Markus Heilig -- Subjective drug effects as intermediate phenotypes for substance use / Leah M. Mayo, Abraham A. Palmer, Harriet de Wit -- Developmental considerations in gene identification efforts / Danielle M. Dick -- Enhancing addiction genetics via behavioral economic intermediate phenotypes / James MacKillop & John Acker -- Using FMRI to develop intermediate phenotypes for substance use disorders / Rachel E. Thayer & Kent E. Hutchison -- Implicit cognition : an intermediate phenotype for addiction? / Reinout W. Wiers, Thomas E. Gladwin & Eske D. Derks -- Role of genetics in addiction and the expectancy principle / Mark S. Goldman & Richard R. Reich -- Intermediate phenotypes for alcohol use and alcohol dependence : empirical findings and conceptual issues / Michael Windle -- Epigenetic effects as intermediate phenotypes / Beach, S.R.H., Gerrard, M., Brody, G.H., Simons, R.L., Kogan, S. M., Gibbons, F.X., Philibert, R.A. -- Differential sensitivity to context : GABRG1 enhances the acquisition of prototypes that serve as intermediate phenotypes for substance use / Ronald L. Simons, Man Kit Lei, Steven R.H. Beach, Gene H. Brody, Robert A. Philibert, Frederick X. Gibbons, Meg Gerrard -- From genes to behavior change : treatment response as an intermediate phenotype / Courtney J. Stevens, Hollis C. Karoly, Renee E. Magnan, and Angela D. Bryan -- Using intermediate phenotypes to bridge the gap between human and mouse genetics / Clarissa C. Parker & Abraham A. Palmer.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Compulsive behaviorx| Genetic aspects.=| ^A6384;

650 0 a| Substance abusex| Genetic aspects.=| ^A317;

650 0 a| Phenotype.=| ^A4005;

650 12 a| Substance-Related Disordersx| genetics.=| ^A943554;

650 22 a| Phenotype.=| ^A918918;

655 0 a| Electronic books.=| ^A491897;

700 1 a| MacKillop, James,d| 1975-=| ^A1151497;

700 1 a| Munafò, Marcus,d| 1972-=| ^A1201295;

856 40 z| Full text available from MIT Press Direct to Open Backfile STEAM Monographs D2Ou| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fdoi.org%2F10.7551%2Fmitpress%2F9391.001.0001%3Flocatt%3Dmode%3Alegacy;

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Genetic influences on addiction an intermediate phenotype approach / edited by James MacKillop and Marcus R. Munafò.

Other author	MacKillop, James, 1975-
Other author	Munafò, Marcus, 1972-
Format	Electronic
Publication Info	Cambridge, Massachusetts : The MIT Press, [2013]
Description	x, 386 pages : illustrations ; 24 cm
Supplemental Content	Full text available from MIT Press Direct to Open Backfile STEAM Monographs D2O
Subjects	Compulsive behavior--Genetic aspects. Substance abuse--Genetic aspects. Phenotype. Substance-Related Disorders--genetics. Phenotype.

Contents	An intermediate phenotype approach to addiction genetics / James MacKillop & Marcus R. Munafò -- Electrophysiological intermediate phenotypes for the detection of genetic influences on alcoholism / Mary-Anne Enoch -- Differential metabolism of alcohol as an intermediate phenotype of risk for alcohol use disorders : alcohol and aldehyde dehydrogenase variants / Tamara L. Wall, Susan Luczak, Daria Orlowska, and Danielle Pandika -- Nicotine metabolism as an intermediate phenotype / Meghan J. Chenoweth & Rachel F. Tyndale -- Subjective responses to alcohol as an endophenotype : implications for alcoholism etiology and treatment development / Lara A. Ray & Markus Heilig -- Subjective drug effects as intermediate phenotypes for substance use / Leah M. Mayo, Abraham A. Palmer, Harriet de Wit -- Developmental considerations in gene identification efforts / Danielle M. Dick -- Enhancing addiction genetics via behavioral economic intermediate phenotypes / James MacKillop & John Acker -- Using FMRI to develop intermediate phenotypes for substance use disorders / Rachel E. Thayer & Kent E. Hutchison -- Implicit cognition : an intermediate phenotype for addiction? / Reinout W. Wiers, Thomas E. Gladwin & Eske D. Derks -- Role of genetics in addiction and the expectancy principle / Mark S. Goldman & Richard R. Reich -- Intermediate phenotypes for alcohol use and alcohol dependence : empirical findings and conceptual issues / Michael Windle -- Epigenetic effects as intermediate phenotypes / Beach, S.R.H., Gerrard, M., Brody, G.H., Simons, R.L., Kogan, S. M., Gibbons, F.X., Philibert, R.A. -- Differential sensitivity to context : GABRG1 enhances the acquisition of prototypes that serve as intermediate phenotypes for substance use / Ronald L. Simons, Man Kit Lei, Steven R.H. Beach, Gene H. Brody, Robert A. Philibert, Frederick X. Gibbons, Meg Gerrard -- From genes to behavior change : treatment response as an intermediate phenotype / Courtney J. Stevens, Hollis C. Karoly, Renee E. Magnan, and Angela D. Bryan -- Using intermediate phenotypes to bridge the gap between human and mouse genetics / Clarissa C. Parker & Abraham A. Palmer.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2013011177
ISBN	9780262019699 (hardcover : alk. paper)
ISBN	0262019698 (hardcover : alk. paper)

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Genetic influences on addiction an intermediate phenotype approach / edited by James MacKillop and Marcus R. Munafò.

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