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020 a| 9780262045216q| (hardcover);

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245 00 a| Rethinking cancerh| [electronic resource] :b| a new paradigm for the post genomics era /c| edited by Bernhard Strauss, Marta Bertolaso, Ingemar Ernberg, and Mina J. Bissell.;

260 a| Cambridge, Massachusetts :b| The MIT Press,c| [2021];

300 a| xv, 413 pages :b| illustrations ;c| 24 cm;

490 1 a| Vienna series in theoretical biology;

504 a| Includes bibliographical references and index.;

505 0 a| The search for progress and a new theory framework in cancer research / Marta Bertolaso and Bernhard Strauss -- Cancer as a system : hard lessons from physics, and a way forward / Thea J. Newman -- The logic of cancer treatment : Why it is so hard to cure cancer / Sui Huang -- The cell attractor concept as a tool to advance our understanding of cancer / Ingemar Ernberg -- Adaptation of molecular interaction networks in cancer cells / Peter Csermely -- The role of genomic dark-matter in cancer--using AI to shine a light on it : why cancer genes are not the whole story / Kahn Rhrissorrakrai and Laxmi Parida -- Darwinism, not mutationalism, for new cancer therapies / Jacob Scott, David Basanta, and Andriy Marusyk -- Cancer as a reversion to an ancestral phenotype / Kimberly J. Bussey and Paul C. W. Davies -- Time and timing in oncology : What therapy scheduling can teach us about cancer biology / Larry Norton -- Tissue tension modulates metabolism and chromatin organization to promote malignancy / Roger Oria, Dhruv Thakar, and Valerie M. Weaver -- Cancer Metabolism & Therapeutic Perspectives : Exploiting Acidic, Nutritional and Oxidative stresses / Maša Ždralević and Jacques Pouysségur -- Corrupted vascular tumor niches confer aggressiveness and chemoresistance to neoplastic cells / Luca V. Capelli, Liron Yoffe, and Giorgio Inghirami -- Metastasis as a tug of war between cell autonomy and microenvironmental control : Re-addressing unresolved questions in cancer metastasis / Courtney König and Christoph A. Klein -- Niche re-construction to revert or transcend the cancer state / Emmy W. Verschuren.;

506 a| Available only to authorized users.;

520 a| "Steps toward an explanatory paradigm for cancer that integrates its different levels of organization (molecular, genetic, etc.) and also integrates theoretical and experimental biology with oncology"--c| Provided by publisher.;

538 a| Mode of access: World Wide Web;

650 12 a| Neoplasmsx| genetics=| ^A920613;

650 22 a| Neoplasmsx| therapy=| ^A918606;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Strauss, Bernhard.?| UNAUTHORIZED;

700 1 a| Bertolaso, Marta.?| UNAUTHORIZED;

700 1 a| Ernberg, Ingemar,d| 1948-?| UNAUTHORIZED;

700 1 a| Bissell, Mina.=| ^A1184334;

830 0 a| Vienna series in theoretical biology.=| ^A691420;

856 40 z| Full text available from MIT Press Direct to Open Backfile STEAM Monographs D2Ou| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fdoi.org%2F10.7551%2Fmitpress%2F12111.001.0001%3Flocatt%3Dmode%3Alegacy;

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Rethinking cancer a new paradigm for the post genomics era / edited by Bernhard Strauss, Marta Bertolaso, Ingemar Ernberg, and Mina J. Bissell.

Format	Electronic
Publication Info	Cambridge, Massachusetts : The MIT Press, [2021]
Description	xv, 413 pages : illustrations ; 24 cm
Supplemental Content	Full text available from MIT Press Direct to Open Backfile STEAM Monographs D2O
Subjects	Neoplasms--genetics. Neoplasms--therapy.

Other author/creator	Strauss, Bernhard.
Other author/creator	Bertolaso, Marta.
Other author/creator	Ernberg, Ingemar, 1948-
Other author/creator	Bissell, Mina.
Series	Vienna series in theoretical biology Vienna series in theoretical biology. ^A691420
Contents	The search for progress and a new theory framework in cancer research / Marta Bertolaso and Bernhard Strauss -- Cancer as a system : hard lessons from physics, and a way forward / Thea J. Newman -- The logic of cancer treatment : Why it is so hard to cure cancer / Sui Huang -- The cell attractor concept as a tool to advance our understanding of cancer / Ingemar Ernberg -- Adaptation of molecular interaction networks in cancer cells / Peter Csermely -- The role of genomic dark-matter in cancer--using AI to shine a light on it : why cancer genes are not the whole story / Kahn Rhrissorrakrai and Laxmi Parida -- Darwinism, not mutationalism, for new cancer therapies / Jacob Scott, David Basanta, and Andriy Marusyk -- Cancer as a reversion to an ancestral phenotype / Kimberly J. Bussey and Paul C. W. Davies -- Time and timing in oncology : What therapy scheduling can teach us about cancer biology / Larry Norton -- Tissue tension modulates metabolism and chromatin organization to promote malignancy / Roger Oria, Dhruv Thakar, and Valerie M. Weaver -- Cancer Metabolism & Therapeutic Perspectives : Exploiting Acidic, Nutritional and Oxidative stresses / Maša Ždralević and Jacques Pouysségur -- Corrupted vascular tumor niches confer aggressiveness and chemoresistance to neoplastic cells / Luca V. Capelli, Liron Yoffe, and Giorgio Inghirami -- Metastasis as a tug of war between cell autonomy and microenvironmental control : Re-addressing unresolved questions in cancer metastasis / Courtney König and Christoph A. Klein -- Niche re-construction to revert or transcend the cancer state / Emmy W. Verschuren.
Abstract	"Steps toward an explanatory paradigm for cancer that integrates its different levels of organization (molecular, genetic, etc.) and also integrates theoretical and experimental biology with oncology"-- Provided by publisher.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2020029807
ISBN	9780262045216 (hardcover)

Rethinking cancer a new paradigm for the post genomics era / edited by Bernhard Strauss, Marta Bertolaso, Ingemar Ernberg, and Mina J. Bissell.

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