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010 a| 2023302775;

020 a| 9783527343348;

035 a| (WaSeSS)ssj0002500560;

040 a| DLCb| engc| DLCd| WaSeSS;

049 a| EREEa| NEHH;

050 00 a| MLCM 2024/40868 (T);

245 00 a| Cell culture engineeringh| [electronic resource] :b| recombinant protein production /c| edited by Gyun Min Lee, Helene Faustrup Kildegaard.;

260 a| Weinheim, Germany :b| Wiley-VCH,c| [2020];

300 a| xviii, 418 pages :b| illustrations (some color) ;c| 25 cm.;

490 0 a| Advanced biotechnology ;v| volume 9;

504 a| Includes bibliographical references and index.;

505 0 a| 1. Platform Technology for Therapeutic Protein Production -- 2. Cell Line Development for Therapeutic Protein Production -- 3. Transient Gene Expression-Based Protein Production in Recombinant Mammalian Cells -- 4. Enhancing Product and Bioprocess Attributes Using Genome-Scale Models of CHO Metabolism -- 5. Genome Variation, the Epigenome and Cellular Phenotypes -- 6. Adaption of Generic Metabolic Models to Specific Cell Lines for Improved Modeling of Biopharmaceutical Production and Prediction of Processes -- 7. Toward Integrated Multi-omics Analysis for Improving CHO Cell Bioprocessing -- 8. CRISPR Toolbox for Mammalian Cell Engineering -- 9. CHO Cell Engineering for Improved Process Performance and Product Quality -- 10. Metabolite Profiling of Mammalian Cells -- 11. Current Considerations and Future Advances in Chemically Defined Medium Development for the Production of Protein Therapeutics in CHO Cells -- 12. Host Cell Proteins During Biomanufacturing -- 13. Mammalian Fed-batch Cell Culture for Biopharmaceuticals -- 14. Continuous Biomanufacturing -- 15. Process Analytical Technology and Quality by Design for Animal Cell Culture -- 16. Development and Qualification of a Cell Culture Scale-Down Mode -- References -- Index.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Cell culture.=| ^A3429;

650 0 a| Biotechnology.=| ^A147110;

650 0 a| Bioreactors.=| ^A428021;

650 0 a| Bioengineering.=| ^A50577;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Lee, Gyun Min,d| 1958-?| UNAUTHORIZED;

700 1 a| Kildegaard, Helene Faustrap.?| UNAUTHORIZED;

856 40 z| Full text available from Ebook Central - Academic Completeu| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=5896262;

949 a| CLICK ON WEB ADDRESSw| ASISh| JOYNER188;

949 a| CLICK ON WEB ADDRESSw| ASISh| HSL77;

949 a| CLICK ON WEB ADDRESSw| ASISh| JMUSIC60;

596 a| 1 3 4;

998 a| 6494733;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6494733-1001l| JNETm| JOYNERr| Ys| Yt| JNESSBKu| 11/13/2024x| EBOOKz| JERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6494733-2001l| HSLELECm| HSLr| Ys| Yt| HEBKu| 11/13/2024x| EBOOKz| HERESOURCE;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6494733-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 11/13/2024x| EBOOKz| JERESOURCE;

Cell culture engineering recombinant protein production / edited by Gyun Min Lee, Helene Faustrup Kildegaard.

Other author	Lee, Gyun Min, 1958-
Other author	Kildegaard, Helene Faustrap.
Format	Electronic
Publication Info	Weinheim, Germany : Wiley-VCH, [2020]
Description	xviii, 418 pages : illustrations (some color) ; 25 cm.
Supplemental Content	Full text available from Ebook Central - Academic Complete
Subjects	Cell culture. Biotechnology. Bioreactors. Bioengineering.

Series	Advanced biotechnology ; volume 9
Contents	1. Platform Technology for Therapeutic Protein Production -- 2. Cell Line Development for Therapeutic Protein Production -- 3. Transient Gene Expression-Based Protein Production in Recombinant Mammalian Cells -- 4. Enhancing Product and Bioprocess Attributes Using Genome-Scale Models of CHO Metabolism -- 5. Genome Variation, the Epigenome and Cellular Phenotypes -- 6. Adaption of Generic Metabolic Models to Specific Cell Lines for Improved Modeling of Biopharmaceutical Production and Prediction of Processes -- 7. Toward Integrated Multi-omics Analysis for Improving CHO Cell Bioprocessing -- 8. CRISPR Toolbox for Mammalian Cell Engineering -- 9. CHO Cell Engineering for Improved Process Performance and Product Quality -- 10. Metabolite Profiling of Mammalian Cells -- 11. Current Considerations and Future Advances in Chemically Defined Medium Development for the Production of Protein Therapeutics in CHO Cells -- 12. Host Cell Proteins During Biomanufacturing -- 13. Mammalian Fed-batch Cell Culture for Biopharmaceuticals -- 14. Continuous Biomanufacturing -- 15. Process Analytical Technology and Quality by Design for Animal Cell Culture -- 16. Development and Qualification of a Cell Culture Scale-Down Mode -- References -- Index.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2023302775
ISBN	9783527343348

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