Tools

LEADER 06895cam 22006377a 4500

001 on1397572758;

003 OCoLC;

005 20250422153035.0;

006 m o d ;

007 cr un|---aucuu;

008 230923s2023 sz o 000 0 eng d;

019 a| 1396974693a| 1405398195a| 1406510800a| 1407323133a| 1409050481a| 1415218987a| 1480586997;

020 a| 9783031351396q| (electronic bk.);

020 a| 3031351398q| (electronic bk.);

020 z| 303135138X;

020 z| 9783031351389;

024 7 a| 10.1007/978-3-031-35139-62| doi;

035 a| (Sirsi) o1397572758;

049 a| NEHH;

050 4 a| RC112b| .S48 2023;

082 04 a| 616.92| 23/eng/20230925;

245 00 a| Sex and gender differences in infection and treatments for infectious diseases /c| Sabra L. Klein, Craig W. Roberts, editors.;

250 a| 2nd ed.;

260 a| Cham :b| Springer,c| 2023.;

300 a| 1 online resource (281 pages).;

336 a| textb| txt2| rdacontent;

337 a| computerb| c2| rdamedia;

338 a| online resourceb| cr2| rdacarrier;

490 1 a| Current Topics in Microbiology and Immunology ;v| v. 441;

505 0 a| Intro -- Contents -- Genetics of Sex Differences in Immunity -- 1 Evolutionary Perspective -- 2 Sex Chromosomes -- 2.1 X Chromosome Inactivation -- 2.2 Immune-Related Genes on the Sex Chromosomes -- 2.3 Sex Chromosome Abnormalities and the Immune System -- 3 Experimental Models for Studying the Sex Effect on Immunity -- 3.1 Four Core Genotypes Mouse Model -- 3.2 Human Cell Lines with Sex Chromosome Aberrations -- 3.3 Additional Mouse Models -- 4 Female-Specific States and Their Immune Consequences -- 4.1 Pregnancy as a Graft -- 4.2 Microchimerism in Fetal Cells -- 5 Concluding Remarks;

504 a| Bibliography -- The Influence of Sex Hormones and X Chromosome in Immune Responses -- 1 Introduction -- 2 Sex Hormone Signaling and X Chromosome Dosage Effects -- 2.1 Sex Steroid Hormones Signaling -- 2.2 X Chromosome Gene Dosage and X Chromosome Inactivation Escape -- 3 Biological Role of Sex-Linked Factors in Autoimmunity -- 3.1 Sex Hormone and X Chromosome Regulation in Organ-Specific Autoimmunity: The Example of Multiple Sclerosis. -- 3.2 Sex Hormones and X Chromosome Effects in Systemic Autoimmunity (SLE);

505 8 a| 4 Sex Differences in Allergic Asthma: A Prominent Role of Sex Steroid Hormone Signaling -- 4.1 Sex Bias in Asthma Prevalence and Severity -- 4.2 Impact of Sex Hormones in Type 2 Mediated Allergic Airway Inflammation -- 5 Biological Sex Influences Natural Immunity to Neonatal Pathogens and Cancer -- 5.1 Sex-Biased Dimorphism in Bloodstream Infections: The Role of Estrogens/Peritoneal Macrophages/B-1 Cells Axis -- 5.2 Sex Dimorphism in Solid Tumor Control: From Innate to Acquired Immunity -- References -- Sex Differences in HIV Infection -- 1 Introduction -- 2 Sex Differences in HIV Acquisition;

505 8 a| 3 Sex Differences in HIV Pathogenesis -- 4 Immune Mechanisms Underlying Sex Differences -- 5 Sex Differences in ART-Treated Disease -- 6 Summary -- References -- Effects of Biological Sex and Pregnancy on SARS-CoV-2 Pathogenesis and Vaccine Outcomes -- 1 Sex Differences in Viral Pathogenesis -- 2 Sex Differences in SARS-CoV-2 Pathogenesis -- 2.1 SARS-CoV-2 Entry, Replication, and Transmission -- 2.2 Development of Innate and Adaptive Immune Responses -- 2.3 Sex Differences in Post-Acute Sequelae SARS-CoV-2 Infection (PASC) -- 2.4 Comorbidities, Sex Difference, and COVID-19;

505 8 a| 2.5 Role of Sex Steroids -- 2.6 Role of Genetic Variations -- 3 Pregnancy and SARS-CoV-2 Pathogenesis -- 4 Sex Differences in COVID-19 Vaccine Outcomes -- 4.1 Immunogenicity -- 4.2 Effectiveness -- 4.3 Vaccine Reactogenicity -- 5 Pregnancy and COVID-19 Vaccines -- 6 Conclusions and Future Directions -- References -- Biological Sex and Pregnancy Affect Influenza Pathogenesis and Vaccination -- 1 Introduction -- 2 Sex Differences in Influenza Pathogenesis -- 2.1 Seasonal Influenza Epidemics -- 2.2 Outbreaks of Avian Influenza -- 2.3 Influenza A Virus Pandemics;

500 a| 2.4 Animal Models of Sex Differences in Influenza Pathogenesis;

520 a| This fully revised and significantly expanded second edition examines sex and gender differences in the immune system's response to bacterial, viral, and parasitic infections. The volume discusses both common and distinct molecular mechanisms that mediate these differences and illustrates how responses to vaccines may differ between the sexes and in pregnant individuals. Special emphasis is placed on the interplay between hormones and the immune system in the pathogenesis of HIV, SARS-CoV-2, influenza, malaria, tuberculosis, and amebiasis. This second edition includes completely rewritten chapters as well as all new contents. This book is intended for researchers in academia and industry as well as clinicians in the fields of microbiology, immunology, and pharmacology. By expanding knowledge in sex and gender medicine as a basis for developing personalized treatment strategies, the book contributes to UN Sustainable Development Goals 3 (health and well-being) and 5 (gender equality).;

588 0 a| Online resource; title from PDF title page (SpringerLink, viewed September 25, 2023).;

650 0 a| Communicable diseasesx| Sex factors.=| ^A824;

650 0 a| Communicable diseasesx| Treatmentx| Sex factors.=| ^A824;

650 0 a| Sex factors in disease.=| ^A157999;

650 2 a| Sex Factors.0| (DNLM)D012737=| ^A920113;

700 1 a| Klein, Sabra L.=| ^A1009543;

700 1 a| Roberts, Craig W.=| ^A1478042;

758 i| has work:a| Sex and gender differences in infection and treatments for infectious diseases (Text)1| https://id.oclc.org/worldcat/entity/E39PCFyVPwQgjfWcrQGPJrb6JC4| https://id.oclc.org/worldcat/ontology/hasWork;

830 0 a| Current topics in microbiology and immunology ;v| v. 441.=| ^A654827;

856 40 z| Direct link to eBooku| https://ebookcentral.proquest.com/lib/eastcarolina/detail.action?docID=30739089;

949 a| CLICK ON WEB ADDRESSw| ASISh| HSL102p| $185.220| HSLo| HMT;

949 a| CLICK ON WEB ADDRESSw| ASISh| JOYNER96o| HMT;

994 a| C0b| NEH;

596 a| 1 4;

998 a| 6565716;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6565716-1001l| HSLELECm| HSLp| $185.22r| Ys| Yt| HGENEBKu| 4/8/2025x| EBOOKz| HERESOURCE0| HSLo| .STAFF. HMT;

999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6565716-2001l| JNETm| JOYNERr| Ys| Yt| JNE3BKu| 4/8/2025x| EBOOKz| JERESOURCEo| .STAFF. HMT;

Sex and gender differences in infection and treatments for infectious diseases / Sabra L. Klein, Craig W. Roberts, editors.

Other author	Klein, Sabra L.
Other author	Roberts, Craig W.
Format	Electronic
Edition	2nd ed.
Publication Info	Cham : Springer, 2023.
Description	1 online resource (281 pages).
Supplemental Content	Direct link to eBook
Subjects	Communicable diseases--Sex factors. Communicable diseases--Treatment. --Sex factors. Sex factors in disease. Sex Factors.

Series	Current Topics in Microbiology and Immunology ; v. 441 Current topics in microbiology and immunology ; v. 441. ^A654827
Contents	Intro -- Contents -- Genetics of Sex Differences in Immunity -- 1 Evolutionary Perspective -- 2 Sex Chromosomes -- 2.1 X Chromosome Inactivation -- 2.2 Immune-Related Genes on the Sex Chromosomes -- 2.3 Sex Chromosome Abnormalities and the Immune System -- 3 Experimental Models for Studying the Sex Effect on Immunity -- 3.1 Four Core Genotypes Mouse Model -- 3.2 Human Cell Lines with Sex Chromosome Aberrations -- 3.3 Additional Mouse Models -- 4 Female-Specific States and Their Immune Consequences -- 4.1 Pregnancy as a Graft -- 4.2 Microchimerism in Fetal Cells -- 5 Concluding Remarks
Contents	4 Sex Differences in Allergic Asthma: A Prominent Role of Sex Steroid Hormone Signaling -- 4.1 Sex Bias in Asthma Prevalence and Severity -- 4.2 Impact of Sex Hormones in Type 2 Mediated Allergic Airway Inflammation -- 5 Biological Sex Influences Natural Immunity to Neonatal Pathogens and Cancer -- 5.1 Sex-Biased Dimorphism in Bloodstream Infections: The Role of Estrogens/Peritoneal Macrophages/B-1 Cells Axis -- 5.2 Sex Dimorphism in Solid Tumor Control: From Innate to Acquired Immunity -- References -- Sex Differences in HIV Infection -- 1 Introduction -- 2 Sex Differences in HIV Acquisition
Contents	3 Sex Differences in HIV Pathogenesis -- 4 Immune Mechanisms Underlying Sex Differences -- 5 Sex Differences in ART-Treated Disease -- 6 Summary -- References -- Effects of Biological Sex and Pregnancy on SARS-CoV-2 Pathogenesis and Vaccine Outcomes -- 1 Sex Differences in Viral Pathogenesis -- 2 Sex Differences in SARS-CoV-2 Pathogenesis -- 2.1 SARS-CoV-2 Entry, Replication, and Transmission -- 2.2 Development of Innate and Adaptive Immune Responses -- 2.3 Sex Differences in Post-Acute Sequelae SARS-CoV-2 Infection (PASC) -- 2.4 Comorbidities, Sex Difference, and COVID-19
Contents	2.5 Role of Sex Steroids -- 2.6 Role of Genetic Variations -- 3 Pregnancy and SARS-CoV-2 Pathogenesis -- 4 Sex Differences in COVID-19 Vaccine Outcomes -- 4.1 Immunogenicity -- 4.2 Effectiveness -- 4.3 Vaccine Reactogenicity -- 5 Pregnancy and COVID-19 Vaccines -- 6 Conclusions and Future Directions -- References -- Biological Sex and Pregnancy Affect Influenza Pathogenesis and Vaccination -- 1 Introduction -- 2 Sex Differences in Influenza Pathogenesis -- 2.1 Seasonal Influenza Epidemics -- 2.2 Outbreaks of Avian Influenza -- 2.3 Influenza A Virus Pandemics
Abstract	This fully revised and significantly expanded second edition examines sex and gender differences in the immune system's response to bacterial, viral, and parasitic infections. The volume discusses both common and distinct molecular mechanisms that mediate these differences and illustrates how responses to vaccines may differ between the sexes and in pregnant individuals. Special emphasis is placed on the interplay between hormones and the immune system in the pathogenesis of HIV, SARS-CoV-2, influenza, malaria, tuberculosis, and amebiasis. This second edition includes completely rewritten chapters as well as all new contents. This book is intended for researchers in academia and industry as well as clinicians in the fields of microbiology, immunology, and pharmacology. By expanding knowledge in sex and gender medicine as a basis for developing personalized treatment strategies, the book contributes to UN Sustainable Development Goals 3 (health and well-being) and 5 (gender equality).
General note	2.4 Animal Models of Sex Differences in Influenza Pathogenesis
Bibliography note	Bibliography -- The Influence of Sex Hormones and X Chromosome in Immune Responses -- 1 Introduction -- 2 Sex Hormone Signaling and X Chromosome Dosage Effects -- 2.1 Sex Steroid Hormones Signaling -- 2.2 X Chromosome Gene Dosage and X Chromosome Inactivation Escape -- 3 Biological Role of Sex-Linked Factors in Autoimmunity -- 3.1 Sex Hormone and X Chromosome Regulation in Organ-Specific Autoimmunity: The Example of Multiple Sclerosis. -- 3.2 Sex Hormones and X Chromosome Effects in Systemic Autoimmunity (SLE)
Source of description	Online resource; title from PDF title page (SpringerLink, viewed September 25, 2023).
Issued in other form	Print version: Klein, Sabra L. Sex and Gender Differences in Infection and Treatments for Infectious Diseases Cham : Springer International Publishing AG,c2023 9783031351389
ISBN	9783031351396 (electronic bk.)
ISBN	3031351398 (electronic bk.)
Standard identifier#	10.1007/978-3-031-35139-6

Availability

Library	Location	Call Number	Status	Item Actions
	Electronic Resources	Access Content Online	✔ Available

Sex and gender differences in infection and treatments for infectious diseases / Sabra L. Klein, Craig W. Roberts, editors.

Click here for more information about this title

Availability