Biology of infectious disease : from molecules to ecosystems / Michael G. Milgroom.

Author/creator Milgroom, Michael G.
Format Electronic
PublicationCham : Springer, 2024.
Description1 online resource (334 pages)
Supplemental ContentDirect link to eBook
Subjects

Contents Intro -- Preface -- Acknowledgments -- Contents -- 1: Introduction to Infectious Diseases -- 1.1 Current Impact of Human Infectious Diseases: The Good News -- 1.2 Emergence and Reemergence of Human Infectious Diseases: The Bad News -- 1.3 Infectious Diseases in Animals -- 1.4 Infectious Diseases in Plants -- 1.5 Biology and the Need for Better Understanding of Infectious Diseases -- 1.6 Chapter Summary -- Further Reading -- 2: The Germ Theory Paradigm -- 2.1 Perceptions of Infectious Diseases Before the Germ Theory -- 2.2 Early Contributions to Germ Theory
Contents 2.3 Louis Pasteur's Contributions to the Germ Theory -- 2.4 Robert Koch's Contributions to the Germ Theory -- 2.5 Major Advancements Since the Acceptance of Germ Theory -- 2.6 Contributions of Germ Theory to Combating Disease -- 2.6.1 Water, Sanitation, and Hygiene -- 2.6.2 Vector Control -- 2.6.3 Vaccination -- 2.6.4 Antibiotics -- 2.7 Chapter Summary -- Further Reading -- 3: Host-Microbe Interactions and Infectious Disease -- 3.1 Microbes as Pathogens -- 3.2 Basic Concepts in Host-Microbe Interactions -- 3.3 Temporal Progression of a Host-Microbe Interaction
Contents 3.4 The Diversity of Host-Microbe Interactions: Mutualism, Commensalism, and Parasitism -- 3.5 What Is a Pathogen? Pathogenicity and Virulence -- 3.6 Damage-Response Framework -- 3.7 An Interaction-Centric Perspective on Disease -- 3.8 The Environmental Context of Host-Microbe Interactions -- 3.9 Chapter Summary -- Further Reading -- 4: Viruses -- 4.1 Viral Morphology -- 4.2 Viral Genomes -- 4.3 Evolutionary Origin of Viruses -- 4.4 Classification of Viruses by Production of Messenger RNA (mRNA) -- 4.5 Viral Gene Expression and Pathogenesis
Contents 4.6 Mutation and Recombination/Reassortment in Viruses -- 4.7 Viral Infection Cycles -- 4.8 Positive-Sense ssRNA Viruses: Poliovirus -- 4.9 dsDNA Viruses: Adenovirus -- 4.10 Negative-Sense ssRNA Viruses: Influenza A Virus -- 4.11 Retroviruses: HIV -- 4.12 Viruses of Bacteria and Archaea -- 4.13 Plant Viruses: Tobacco Mosaic Virus -- 4.14 Prions -- 4.15 Chapter Summary -- Further Reading -- 5: Bacteria -- 5.1 Bacterial Morphology -- 5.2 Biofilms -- 5.3 Bacterial Genomes -- 5.4 Horizontal Gene Transfer -- 5.5 Bacterial Pathogenesis and Virulence Factors -- 5.6 E. coli
Contents 5.7 Vibrio cholerae -- 5.8 Staphylococcus aureus -- 5.9 Mycobacterium tuberculosis -- 5.10 Bacterial Plant Pathogens -- 5.11 Chapter Summary -- Further Reading -- 6: Protozoa -- 6.1 Protozoan Morphology -- 6.2 Protozoan Reproduction -- 6.2.1 Asexual Reproduction -- 6.2.2 Sexual Reproduction -- 6.3 Protozoan Genomics -- 6.4 Protozoan Life Cycles -- 6.5 Entamoeba histolytica -- 6.6 Plasmodium falciparum -- 6.7 Toxoplasma gondii -- 6.8 Trypanosomes -- 6.8.1 Trypanosoma brucei -- 6.8.2 Trypanosoma cruzi -- 6.9 Leishmania Species -- 6.10 Protozoan Parasites of Animals
Abstract This textbook provides a broad introduction to the biological processes underlying infectious diseases in a range of hosts and pathogens. The text covers topics at all levels of biological organization, from the molecular and cellular level, organismal level, and population and ecosystem level, and goes well beyond infectious diseases of humans. The details of how microbes interact with their hosts are unique for each interaction, but emphasis is on the common principles of host-pathogen interactions that result in disease. Biology of Infectious Disease: From Molecules to Ecosystems is aimed at undergraduate and early graduate-level students in biology or public health, including pre-medical and pre-public-health students, who are interested in a broad introduction to infectious disease but do not have any previous background in microbiology or immunology.
General note6.11 Protozoan Parasites of Plants
Issued in other formPrint version: Milgroom, Michael G. Biology of Infectious Disease Cham : Springer International Publishing AG,c2024 9783031389405
ISBN9783031389412 (electronic bk.)
ISBN3031389417 (electronic bk.)
Standard identifier# 10.1007/978-3-031-38941-2

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