Gastroesophageal Reflux Disease : From Pathophysiology to Treatment.

Author/creator Schlottmann, Francisco
Other author Herbella, Fernando A. M.
Other author Patti, Marco G.
Format Electronic
Edition1st ed.
PublicationCham : Springer, 2024.
Copyright Date©2023
Description1 online resource (166 pages)
Supplemental ContentDirect link to eBook
Subjects

Contents Intro -- Contents -- Esophageal Anatomy: The Antireflux Barrier -- Introduction -- Historical Aspects -- The Anti Reflux Barrier Components -- Conclusions -- References -- Pathophysiology of Gastroesophageal Reflux Disease -- Introduction -- Natural Anti-reflux Mechanism -- Trans-Diaphragmatic Pressure -- GERD in Different Clinical Scenarios -- Refluxate Characteristics and GERD -- Conclusions -- References -- Clinical Presentation of Gastroesophageal Reflux Disease: Esophageal and Extraesophageal Manifestations -- Introduction -- Esophageal Symptoms -- Extraesophageal Symptoms -- Ear-Nose-Throat Symptoms -- Thoracic Symptoms -- Pulmonary Symptoms -- Conclusions -- References -- Refractory Gastroesophageal Reflux Disease. Real Reflux or Fake Reflux? -- Introduction -- Diagnostic Evaluation of GERD. Distinguishing "Real" from "Fake" Reflux. -- Limitations of the Symptomatic Evaluation -- Limitations of Endoscopy in the Diagnosis of GERD -- A Complete work-up: The Key for Success -- Persistent Symptoms After Antireflux Surgery: Distinguishing "Real" from "Fake" Reflux -- Conclusions -- References -- Radiologic Evaluation of Gastroesophageal Reflux Disease -- Introduction -- Barium Esophagram or Esophagography -- Technique -- Gerd Evaluation -- Hiatal Hernias -- Computed Tomography -- Conclusions -- References -- Endoscopic Evaluation of Gastroesophageal Reflux Disease -- Introduction -- Indications for EGD -- Endoscopic Findings -- Conclusions -- Conflicts of Interest -- References -- Esophageal Manometry and Ambulatory pH Monitoring -- Introduction -- Esophageal Manometry -- Indications and Contraindications -- Technique -- Interpretation -- The Lower Esophageal Sphincter and the Esophagogastric Junction -- Esophageal Body -- Upper Esophageal Sphincter -- Ambulatory pH Monitoring -- Indications and Contraindications -- Technique -- Interpretation.
Contents GERD Diagnosis -- Reflux Height -- Symptoms -- Conclusions -- Conflicts of Interest -- References -- Medical Therapy for Gastroesophageal Reflux Disease -- Lifestyle Modifications -- Non-proton Pump Inhibitor-Based Medical Therapy -- Non-absorbable Agents -- Inhibitors of Transient Lower Esophageal Sphincter Relaxations (TLESRs) -- Anti-secretory Agents -- Potassium Competitive Acid Blockers (P-CABs) -- Proton Pump Inhibitors (PPIs) -- Brief History of PPIs -- Pharmacology of PPIs -- Omeprazole -- Esomeprazole -- Pantoprazole -- Lansoprazole -- Dexlansoprazole -- Rabeprazole -- Drug Interactions -- Long-Term PPI Therapy: Safety Concerns -- Approach to Pharmacologic Therapy -- Conclusions -- References -- Endoscopic Management of Gastroesophageal Reflux Disease -- Introduction -- Endoscopic Diagnosis of GERD -- Endoscopic Examination for GERD -- Ambulatory pH Testing -- Endoscopic Treatment of GERD -- Radiofrequency Ablation (RFA) -- Transoral Incisionless Fundoplication (TIF) -- Anti-reflux Mucosectomy (ARMS) and Anti-reflux Mucosal Ablation (ARMA) -- Conclusions -- References -- Laparoscopic Antireflux Surgery -- Introduction -- Preoperative Work-Up -- Surgical Technique -- Positioning of the Patient and Surgical Team -- Trocar Placement -- Division of the Gastrohepatic Ligament -- Division of the Phrenoesophageal Membrane -- Division of Short Gastric Vessels -- Placement of Penrose Drain and Mediastinal Dissection -- Closure of the Esophageal Hiatus -- Fundoplication -- Final Inspection -- Postoperative Care -- References -- Robotic Antireflux Surgery -- Introduction -- Robotic Antireflux Surgery -- Preoperative Evaluation -- Patient Positioning and Port Placement -- Operative Technique -- Postoperative Care -- Conclusions -- References -- Gastroesophageal Reflux Disease in Obese Patients -- Introduction -- Pathophysiology.
Contents Lower Esophageal Sphincter Abnormalities -- Altered Transdiaphragmatic Pressure Gradient -- Defective Esophageal Clearance -- Altered Hormone Profile -- Diet -- Treatment of GERD in Obese Patients -- Medical Therapy -- Surgical Treatment -- Conclusions -- References -- Gastroesophageal Reflux Disease After Bariatric Surgery -- Introduction -- GERD and Obesity -- GERD and Bariatric Surgery -- Diagnosis of GERD After Bariatric Surgery -- Management of GERD After Bariatric Surgery -- Medical Therapy -- Endoscopic Procedures -- Surgical Procedures -- Conclusions -- References -- Failed Antireflux Surgery -- Introduction -- Defining What is a Failed Antireflux Operation -- Anatomic Causes of Antireflux Surgery Failures -- Physiologic Causes of Antireflux Surgery Failures -- Evaluation of the Patient with Recurrent Symptoms After a Fundoplication -- Management/Treatment -- Medical/Conservative Care for Nonoperative Adverse Events -- Conclusions -- References -- Gastroesophageal Reflux Disease, Barrett's Esophagus and Beyond -- Introduction -- Pathophysiology -- Diagnosis of Barrett's Esophagus -- Management of Barrett's Esophagus -- Endoscopic Therapies -- Surgical Therapies -- Conclusions -- References -- Gastroesophageal Reflux Disease. From Heartburn to Lung Fibrosis and Beyond -- Introduction -- GERD and IPF -- GERD and Lung Transplantation -- Conclusions -- References.
Abstract This comprehensive book on reflux disease, edited by Francisco Schlottmann, Fernando A. M. Herbella, and Marco G. Patti, explores the anatomy, diagnosis, and treatment of gastroesophageal reflux disease (GERD). It covers the physiological and anatomical aspects of the esophagus and the antireflux barrier, providing insights into medical and surgical management strategies for reflux disease. The book is intended for medical professionals and researchers, offering detailed discussions on topics such as esophageal manometry, pH monitoring, endoscopic and radiologic evaluation, and various surgical interventions. It also addresses the condition's presentation in special populations, such as obese patients and those post-bariatric surgery. Generated by AI
Source of descriptionDescription based on publisher supplied metadata and other sources.
Source of descriptionPart of the metadata in this record was created by AI, based on the text of the resource.
Issued in other formPrint version: Schlottmann, Francisco Gastroesophageal Reflux Disease Cham : Springer,c2024 9783031482403
ISBN9783031482410
ISBN3031482417

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