Infertility in the male / edited by Larry I. Lipshultz, Stuart S. Howards, Craig S. Niederberger, Dolores J. Lamb.

Format Electronic
EditionFifth edition.
PublicationCambridge, United Kingdom ; New York, NY : Cambridge University Press, [2023]
Description1 online resource (xvii, 565 pages) : illustrations (chiefly color)
Supplemental ContentDirect link to eBook
Subjects

Other author/creatorLipshultz, Larry I., 1942- editor. https://id.oclc.org/worldcat/entity/E39PCjwT9QxRbDb6thHMxkqpvb
Other author/creatorHowards, Stuart S., 1937- editor. https://id.oclc.org/worldcat/entity/E39PCjrHJjGGCjjCKKFmpx8MxC
Other author/creatorNiederberger, Craig S., editor.
Other author/creatorLamb, Dolores, editor.
Contents Cover -- Half-title -- Title page -- Copyright information -- Contents -- Contributors -- Foreword -- Abbreviations -- Introduction -- References -- Section 1: Scientific Foundations of Male Infertility -- Chapter 1 Anatomy and Embryology of the Male Reproductive Tract and Gonadal Development, the Epididymis, and Accessory Sex Organs -- Introduction -- Fertilization to Germ Layers -- Renal Development -- Bladder Development -- Male Gonadal and Genital Duct Development -- Female Gonadal Development -- Male External Genitalia -- Conclusion -- Further Reading -- References
Contents Chapter 2 Cellular Architecture and Function of the Testis -- Introduction -- Cellular Architecture of the Testis -- Seminiferous Tubules and the Epithelial Cycle of Spermatogenesis -- Cell Polarity, Planar Cell Polarity, and Cell Polarity and Planar Cell Polarity Proteins -- Cell Polarity and Regulatory Proteins -- Planar Cell Polarity -- A Local Regulatory Axis to Support Changes of Cellular Architecture during the Epithelial Cycle -- The F5-Peptide -- The NC1-Peptide -- Background -- Type IV Collagens in the Testis -- NC1-Peptide from Collagen ?3(IV) Chain -- The LG3/4/5-Peptide
Contents Future Perspectives and Conclusion -- Acknowledgments -- References -- Chapter 3 Maturation and Function of Sperm -- Introduction -- Spermatogenesis -- Epididymal Development, Structure, and Function -- Epididymal Development -- General Epididymal Structure -- Initial Segment -- Efferent Ducts -- Caput -- Corpus -- Cauda -- Effects of Aging on the Epididymis -- General Function of the Epididymis -- Molecular Composition of the Epididymis -- Cellular Composition of the Epididymis and Blood-Epididymal Barrier -- Macrophages -- Dendritic Cells -- Basal Cells -- Blood-Epididymis Barrier
Contents Gene Expression in the Epididymis -- Androgen Receptor (AR) -- Estrogen Receptor (ESR) -- Phosphatase and Tensin Homolog (PTEN) -- Dicarbonyl and L-Xylulose Reductase (DCXR, P34H) -- Adhesion G Protein-Coupled Receptor (ADGRG2) -- Human Sperm Antigen 11 (SPAG11, HE2) -- Binder of Sperm Protein Homolog 1 (BSPH1) -- Niemann Pick Disease Type C2 (NPC2, HE1) -- ADAM Metallopeptidase Domain 7 (ADAM7) -- Cysteine-Rich Secretory Protein 1 (CRISP1) -- Cluster of Differentiation 52 (CD52) -- Adenylate Kinases 1 and 7 (AK1 and AK7) -- Defensin Beta (DEFB) -- Lipocalin (LCN) -- Aquaporin (AQP) -- Other
Contents Sperm Transport and Maturation Beyond the Epididymis -- Sperm Transport from the Epididymis -- Sperm Transport Within the Female Genital Tract -- Sperm Maturation Beyond the Epididymis and Within the Female Genital Tract -- Capacitation of Sperm -- Sperm Channels Involved in Capacitation -- Intracellular Alkalinization -- Calcium Signaling -- Membrane Polarization -- Epididymal Dysfunction and Male Infertility -- Epididymal Disorders and Male Infertility -- Congenital Defects of the Epididymis -- Congenital Absence of the Vas Deferens -- Cryptorchidism
Abstract "The 5th edition of Infertility in the Male continues to be the gold standard in the field of Infertility Urology. The editors represent three generations of pioneers and leaders in the field. Within the text, each has brought their own editorial skills and writing acumen. This classic is up to date as in the past. This is a rapidly changing field stimulated by the introduction to society of IVF, ICSI and MESA. 40 years ago, infertility in the male was a sleepy, not very interesting pursuit. Today it is exploding with new information, cures, and insights. As in many fields, genetics has had a profound affect. Surgical procedures as well as basic science research has changed hyperbolically"-- Provided by publisher.
Bibliography noteIncludes bibliographical references and index.
Source of descriptionDescription based on online resource; title from digital title page (viewed on July 12, 2023).
Issued in other formPrint version: Infertility in the male 5th edition. Cambridge, United Kingdom ; New York, NY : Cambridge University Press, 2022 9781108838054
LCCN 2021057952
ISBN9781108937054 electronic book
ISBN1108937055 electronic book
ISBNhardcover
ISBN1108838057
ISBN9781108838054
Standard identifier# 10.1017/9781108937054