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020 a| 9780120885619;

020 a| 0120885611 (hbk.);

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245 00 a| Novel anticancer agentsh| [electronic resource] :b| strategies for discovery and clinical testing /c| editors, Alex A. Adjei, John K. Buolamwini.;

260 a| Amsterdam ;a| Boston :b| Academic Press,;

300 a| xv, 437 p., [20] p. of plates :b| ill. (some col.) ;c| 26 cm.;

504 a| Includes bibliographical references and index.;

505 0 a| A survey of novel molecular targets for anticancer drug discovery -- Microarrays: small spots produce major advances in pharmacogenomics -- Strategies to target chemotherapeutics to tumors -- QSAR and pharmacophore mapping strategies in novel anticancer drug discovery -- Applications of nuclear magnetic resonance and mass spectrometry to anticancer drug discovery -- Antisense strategies for the development of novel cancer therapeutics -- Antibodies and vaccines as novel cancer therapeutics -- Inhibitors as targets for cancer therapy -- Preclinical testing and validation of novel anticancer agents -- Surrogate end points and biomarkers for early trials of novel anticancer agents -- Regulatory considerations in clinical trials of novel anticancer drugs -- Improving the efficacy and safety of anticancer agents: the role of pharmacogenetics -- Imaging of pharmacodynamic end points in clinical trials -- Devising proof-of-concept strategies in oncology clinical trials -- Clinical trial designs for cytostatic agents and agents directed at novel molecular targets -- Cancer gene therapy clinical trials: from the bench to the clinic -- Molecular targets for radiosensitization -- Patient accrual to clinical trials.;

506 a| Available only to authorized users.;

538 a| Mode of access: World Wide Web;

650 0 a| Antineoplastic agentsx| Development.=| ^A1032303;

650 0 a| Antineoplastic agentsx| Testing.=| ^A1335771;

650 2 a| Antineoplastic Agents=| ^A918039;

650 2 a| Drug Therapy=| ^A917921;

650 2 a| Researchx| methods=| ^A918990;

650 2 a| Drug Screening Assays, Antitumor=| ^A1202485;

650 2 a| Clinical Trialsx| methods?| UNAUTHORIZED;

650 2 a| Pharmacogenetics=| ^A923259;

655 0 a| Electronic books.=| ^A491897;

700 1 a| Adjei, Alex A.=| ^A937813;

700 1 a| Buolamwini, John K.=| ^A937812;

856 40 z| Full text available from eBook - Pharmacology, Toxicology and Pharmaceutical Science 1995 - 2006u| https://go.openathens.net/redirector/ecu.edu?url=https%3A%2F%2Fwww.sciencedirect.com%2Fscience%2Fbook%2F9780120885619;

947 a| (OCoLC)ocm60740773;

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999 a| CLICK ON WEB ADDRESSw| ASISc| 1i| 6597343-3001l| MNETm| JMUSICr| Ys| Yt| MNESSBKu| 7/18/2025x| EBOOKz| JERESOURCE;

Novel anticancer agents strategies for discovery and clinical testing / editors, Alex A. Adjei, John K. Buolamwini.

Other author	Adjei, Alex A.
Other author	Buolamwini, John K.
Format	Electronic
Publication Info	Amsterdam ; Boston : Academic Press,
Description	xv, 437 p., [20] p. of plates : ill. (some col.) ; 26 cm.
Supplemental Content	Full text available from eBook - Pharmacology, Toxicology and Pharmaceutical Science 1995 - 2006
Subjects	Antineoplastic agents--Development. Antineoplastic agents--Testing. Antineoplastic Agents Drug Therapy Research--methods. Drug Screening Assays, Antitumor Clinical Trials--methods. Pharmacogenetics

Contents	A survey of novel molecular targets for anticancer drug discovery -- Microarrays: small spots produce major advances in pharmacogenomics -- Strategies to target chemotherapeutics to tumors -- QSAR and pharmacophore mapping strategies in novel anticancer drug discovery -- Applications of nuclear magnetic resonance and mass spectrometry to anticancer drug discovery -- Antisense strategies for the development of novel cancer therapeutics -- Antibodies and vaccines as novel cancer therapeutics -- Inhibitors as targets for cancer therapy -- Preclinical testing and validation of novel anticancer agents -- Surrogate end points and biomarkers for early trials of novel anticancer agents -- Regulatory considerations in clinical trials of novel anticancer drugs -- Improving the efficacy and safety of anticancer agents: the role of pharmacogenetics -- Imaging of pharmacodynamic end points in clinical trials -- Devising proof-of-concept strategies in oncology clinical trials -- Clinical trial designs for cytostatic agents and agents directed at novel molecular targets -- Cancer gene therapy clinical trials: from the bench to the clinic -- Molecular targets for radiosensitization -- Patient accrual to clinical trials.
Bibliography note	Includes bibliographical references and index.
Access restriction	Available only to authorized users.
Technical details	Mode of access: World Wide Web
Genre/form	Electronic books.
LCCN	2006272967
ISBN	9780120885619
ISBN	0120885611 (hbk.)

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Novel anticancer agents strategies for discovery and clinical testing / editors, Alex A. Adjei, John K. Buolamwini.

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