Transmembrane Receptors and Channels.
| Author/creator | Lee, A. G. Editor |
| Format | Electronic |
| Publication Info | Elsevier Science [Imprint] San Diego : Elsevier Science & Technology Books |
| Description | 432 p. ill |
| Supplemental Content | Full text available from eBook - Biochemistry, Genetics and Molecular Biology 1995 - 2006 |
| Subjects |
| Series | Biomembranes. A Multi-Volume Treatise Ser. |
| Summary | Annotation Volume 6 of Biomembranes covers transmembrane receptors and channels. A particularly important role for the membrane is that of passing messages between a cell and its environment. Part I of this volume covers receptors for hormones and growth factors. Here, as in so many other areas of cell biology, the application of the methods of molecular biology have led to the recognition of a number of families of receptors. Typically, such receptors contain an extracellular ligand binding domain, a transmembrane domain, and an intracellular catalytic domain whose activation, as a result of ligand binding, leads to generation of second messengers within the cell and stimulation of a range of cytosolic enzymes. An alternative signaling strategy, exploited in particular in the nervous system, is to use ion channels to allow controlled movement of monovalent (Na+, K+) or divalent (Ca2+) cations in or out of the cell, resulting in changes in membrane potential or alterations in the intracellular concentration of Ca2+. Part II of this volume is concerned with these ion channels and with other, often simpler, ion channel systems whose study can throw light on channel mechanism.<br /> |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| LCCN | 97169007 |
| ISBN | 9781559386630 |
| ISBN | 1559386630 (Trade Cloth) Active Record |
| UPC | 9781559386630 |
| Standard identifier# | 9781559386630 |
| Stock number | 00991439 |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |