Progress in Medicinal Chemistry.
| Author/creator | King, F. D. Author |
| Other author | Oxford,A. W. Author |
| Other author | Ellis,G. P. Author |
| Other author | Luscombe,D. K. Author |
| Format | Electronic |
| Publication Info | Elsevier Science [Imprint] San Diego : Elsevier Science & Technology Books |
| Description | 300 p. 22.000 x 015.000 cm. |
| Supplemental Content | Full text available from Book Series Package - Life Sciences [BSLFSC] |
| Subjects |
| Summary | Annotation This series has a long established reputation for excellent coverage of almost every facet of medicinal chemistry. DESCRIPTION: The Progress in Medicinal Chemistry series is a respected and instructive source of information on the subject. It has a long established reputation for excellent coverage of almost every facet of medicinal chemistry. This volume features a comprehensive account of in vitro and in vivo models and in silico approaches for the prediction of oral absorption and bioavailability. Also discussed is the virtual screening of virtual libraries as a means of identifying lead molecules for drug discovery programs. Includes a thorough review of inhibitors of phosphodiesterase 5 (PDE5) including compounds that have been recently advanced into clinical trials. TABLE OF CONTENTS: Predicting Oral Absorption and Bioavailability; Virtual Screening of Virtual Libraries; -Secretase Inhibitors-From Molecular Probes to New Therapeutics; The Discovery and Development of 5-HT terminal Autoreceptor Antagonists; Orally Bioavailable 3-Adrenergic Agonists as Potential Therapeutic Agents for Obesity and Type II Diabetes; Antagonists of the Corticotropin Releasing Factor Receptor; Phosphodiesterase Type 5 (PDE5) Inhibitors. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| ISBN | 9780444511423 |
| ISBN | 0444511423 (Trade Cloth) Active Record |
| Standard identifier# | 9780444511423 |
| Stock number | 00991439 |