The microbiome and cancer : understanding the role of microorganisms in tumor development and treatment / Nosheen Masood, Azra Yasmin, editors.

Other author Masood, Nosheen.
Other author Yasmin, Azra.
Format Electronic
Publication InfoSingapore : Springer, 2024.
Description1 online resource
Supplemental ContentDirect link to eBook
Subjects
Cancer--Microbiology.
Human body--Microbiology.

Contents Intro -- Foreword -- Preface -- Acknowledgments -- Contents -- Editors and Contributors -- About the Editors -- Contributors -- 1: The Microbiome and Cancer: Understanding the Role of Microorganisms in Tumor Development and Treatment -- 1.1 Introduction -- 1.2 Microbial Metabolites and their Impact -- 1.3 Mechanisms of Microbial Influence on Cancer -- 1.3.1 Implications for Cancer Evasion -- 1.3.2 Metabolic Interactions -- 1.3.3 Direct Interactions with Cancer Cells -- 1.3.4 Microbial Factors Promoting or Inhibiting Tumor Progression -- 1.3.5 Microbiome as a Biomarker for Cancer
Contents 1.3.5.1 Identification of Microbial Signatures in Cancer Patients -- 1.3.6 Diagnostic and Prognostic Applications in Healthcare -- 1.4 Therapeutic Interventions -- 1.4.1 Probiotics and Prebiotics in Cancer Prevention -- 1.5 Fecal Microbiota Transplantation (FMT) -- 1.5.1 Potential Role in Cancer Treatment and Prevention -- 1.5.2 Microbiome-Targeted Therapies -- References -- 2: Microbiome and Its Impact on Human Health: Microbiome in Various Body Organs and Its Association with Human Health and Disease -- 2.1 Human Body Residues of Different Microbiome
Contents 2.2 Human Microbiome Different Role -- 2.3 Microbiota Variation across Human Organs and its Impact on Human Health -- 2.4 Digestive System (Oral Cavity, Gastric, and Intestine) -- 2.5 Role of Microbiome in Human Metabolism -- 2.6 Respiratory System (Nasal Cavity, Pharynx, Larynx, Trachea, and Lungs) -- 2.7 Microbiome for Therapeutic Applications -- 2.8 Probiotic Supplementation -- 2.9 Prebiotic Supplementation -- References -- 3: Bacteria and Cancer -- 3.1 Relationship Between Cancer and Human Microbiome -- 3.2 Role of Bacteria as Cancer Inducer
Contents 3.3 Mechanisms Behind the Carcinogenic Potential of Bacteria -- 3.4 Bacteria Involved in Incidence of Various Types of Cancers and Mechanisms of Carcinogenesis -- 3.5 Association of Bacteria with Various Types of Cancers along with Oncogenic Molecular Pathways -- 3.6 Gastric Cancer -- 3.6.1 Helicobacter pylori and Gastric Carcinogenesis -- 3.7 Gallbladder Cancer -- 3.7.1 Salmonella typhi and Gallbladder Cancer Carcinogenesis -- 3.8 Colorectal Cancer -- 3.8.1 Fusobacterium nucleatum and Colorectal Cancer Carcinogenesis -- 3.9 Lung Cancer
Contents 3.9.1 Chlamydia pneumonia and Lung Cancer Carcinogenesis -- 3.10 Breast Cancer -- 3.11 The Role of Distinct Microbiota in Breast Cancer Tumorigenesis and Metastasis -- 3.12 Role of Bacteria as Tumor Suppressor -- 3.13 Tumor-Targeting Features of Bacteria -- 3.14 Mechanisms of Bacterial Action in Cancer Therapy -- 3.15 Potential Anticancer Mechanisms of Bacteria -- 3.15.1 Anticancer Potential by Triggering Immune Response -- 3.15.1.1 Activation of Cytokines -- 3.15.1.2 Activation of T Cell Lymphocytes -- 3.15.1.3 Activation of Tumor Necrosis
Abstract This book explores the intricate relationship between microorganisms and cancer. It begins by discussing the microbiome of the human body and its role in cancer development. The cellular organization of tumors is also explored in detail. The book then delves into the specific microorganisms that have been associated with various types of cancer. The role of HCV in hepatocellular carcinoma is discussed in depth, as well as cancers associated with EBV. Further, it also explores the link between HPV and urogenital and head and neck cancers, and Kaposis sarcoma-associated Herpes virus. The chapter is dedicated to dispelling myths surrounding Aspergillus and lung cancer and examines the complications associated with fungal infections in cancer treatment. The book then explores the link between parasites and cancer, and the role that protists play in cancer development. Finally, the book concludes with a discussion of cancer management and therapies related to microorganisms. Overall, the book provides a comprehensive overview of the relationship between microorganisms and cancer and sheds light on how this relationship can be harnessed for more effective cancer management and treatment.
Source of descriptionOnline resource; title from PDF title page (SpringerLink, viewed January 7, 2025).
Issued in other formOriginal 9819769477 9789819769476
ISBN9789819769483 (electronic bk.)
ISBN9819769485 (electronic bk.)
Standard identifier# 10.1007/978-981-97-6948-3

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