Gene therapy for neurological disorder : molecular approaches for targeted treatment / Rishabha Malviya, PhD, Arun Kumar Singh, PhD, Priyanshi Goyal, MPharm, Sonali Sundram, MPharm.
| Author/creator | Malviya, Rishabha author. |
| Other author | Singh, Arun Kumar, MPharm, author. |
| Other author | Goyal, Priyanshi, author. |
| Other author | Sundram, Sonali, author. |
| Format | Electronic |
| Edition | First edition. |
| Publication | Palm Bay, FL, USA ; Burlington, ON, Canada : Apple Academic Press, 2025. |
| Description | 1 online resource. |
| Supplemental Content | Direct link to eBook |
| Subjects |
| Contents | Neurodegenerative Disorders and Their Treatment -- Neurodegenerative Disorder: A Mysterious Group of Diseases -- Neurodegenerative Diseases Spread Like Prion Viruses -- Gene Therapy: A Promising Strategy for the Treatment of Brain Disease -- Stem-Cell-Employed Gene Therapy for Neurodegenerative Disorders -- Current Practice and Prospects in Gene Therapy Based on Genomic DNA -- Targeting Oligodendrocytes with Gene-Silencing Sequences through Vector Mediated Transgene Delivery -- Astrocytes: Genetic Treatment Targets for Alzheimer's Disease -- Clinical Studies of Gene Therapy for the Treatment of Neurodegenerative Disorders. |
| Abstract | "Neurological illnesses pose one of the biggest hazards to the healthcare system today. The range of pharmacotherapeutics currently available have a range of palliative effects and are ineffective in treating such neurological illnesses. This new book, Gene Therapy for Neurological Disorders: Molecular Approaches for Targeted Treatment, brings together the latest methods of gene therapy that can be used to treat both inherited and sporadic neurodegenerative diseases. The book presents the most significant advances in gene transfer methods as well as the most recent understandings of the mechanisms behind specific neurodegenerative illnesses, placing these into the context of gene therapy approaches for the central nervous system. The book introduces the basics of neurodegenerative conditions and its physiological basis for their occurrence in humans. It also discusses the various proteins useful in neuro diseases and their viral applications. The book explores how stem cells can be used to learn about the future of gene therapy along with the significance of the sequences that silence genes. It discusses the functionS of astrocytes in the various brain regions, as well as in-vivo research in gene therapy for neurodegenerative disorders. With the latest information on gene therapy in treating neurological disorders, this book is a comprehensive resource on the topic of gene therapy for neurological conditions. This volume will help pharmacologists, clinical researchers, and others to find a solution to treating neurological illnesses."-- Provided by publisher. |
| Bibliography note | Includes bibliographical references and index. |
| Other forms | Issued also in print format. |
| Issued in other form | Print version: Malviya, Rishabha. Gene therapy for neurological disorder. First edition. Palm Bay, FL, USA ; Burlington, ON, Canada : Apple Academic Press, 2025 1774916789 9781774916780 |
| LCCN | 2024038990 |
| ISBN | 9781003494102 (electronic bk.) |
| ISBN | 1003494102 (electronic bk.) |
| ISBN | 9781040052105 (electronic bk. : PDF) |
| ISBN | 104005210X (electronic bk. : PDF) |
| ISBN | 9781040052112 (electronic bk. : EPUB) |
| ISBN | 1040052118 (electronic bk. : EPUB) |
| ISBN | (pbk) |
| Standard identifier# | 9781003494102 |
| Standard identifier# | 10.1201/9781003494102 |
| Stock number | 9781003494102 Taylor & Francis |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |