Charnolophagy in health and disease with special reference to nanotheranostics / Sushil Sharma.
| Author/creator | Sharma, Sushil |
| Format | Electronic |
| Edition | First edition. |
| Publication Info | Boca Raton : CRC Press, Taylor and Francis Group, 2021. |
| Description | 1 online resource (xxii, 584 pages) |
| Supplemental Content | Full text available from Taylor & Francis eBooks |
| Subjects |
| Contents | Charnolophagy as immediate and early autophagy -- Charnolophagy in intramitochondrial and intracellular detoxification -- Charnolophagy as a biomarker of novel drug discovery -- Organ and disease-specific charnolophagy -- Charnolophagy in pressure ulcers -- Charnolophagy in toxicology -- Charnolophagy in congenital diseases -- Charnolophagy in inborn errors of metabolism (recent update) -- Charnolophagy in malnutrition -- Charnolophagy in diet restriction -- Charnolophagy in gastrointestinal disorders -- Charnolophagy in liver diseases -- Charnolophagy in diabetes -- Charnolophagy in obesity -- Charnolohagy in hyperlipidemia -- Charnolophagy in skin and hair diseases -- Charnolophagy in musculoskeletal diseases -- Charnolophagy in pulmonary diseases -- Charnolophagy in cardiovascular diseases -- Charnolophagy in renal diseases -- Charnolophagy in reproductive diseases -- Charnolophagy in opthalamic diseases -- Charnolophagy in neurodegenerative diseases (A) -- Charnolophagy in neurodegenerative diseases (B) -- Charnolophagy in parkinson's disease -- Charnolophagy in alzheimer disease -- Charnolophagy in stroke -- Charnolophagy in inflammatory diseases -- Charnolophagy in cancer (A) -- Charnolophagy in cancer (B) -- Charnolophagy in microbial infections -- Charnolophagy in aging -- Charnolophagy in nanotheranostics (A) -- Charnolophagy in nanotheranostics (B). |
| Abstract | "This book is based on my original discovery of Charnoly body (CB) and illustrates basic molecular mechanism of mitochondrial quality control (MQC) and intracellular detoxification (ICD) by charnolophagy (CP) at the transcriptional and translational level for the targeted, safe, and effective personalized theranostics of neurodegenerative diseases, cardiovascular diseases, chronic pain, inflammation, drug addiction, MDR malignancies, and infectious diseases. The book confers unique strategies and guidelines for the targeted, safe, and effective personalized theranostics of afore-mentioned diseases involving compromised MQC due to functionally-impaired CP, destabilized CS, and IS activation, and its prevention. Diversified physicochemical injuries/insults (DPCI)-induced free radical overproduction trigger CB formation in the most vulnerable cells such as neural progenitor cells and cardiac progenitor cells, derived from induced pluripotent stem cells in the developing embryo. Free radicals are generated as a byproduct of mitochondrial oxidative phosphorylation during ATP synthesis in the electron transport chain"-- Provided by publisher. |
| Bibliography note | Includes bibliographical references and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Source of description | Description based on print version record and CIP data provided by publisher; resource not viewed. |
| Issued in other form | Print version: Charnolophagy in health and disease Boca Raton : CRC Press, Taylor & Francis Group, 2021. 9780367407902 |
| Genre/form | Electronic books. |
| LCCN | 2021702055 |
| ISBN | 9781000298451 ebook |
| ISBN | (hardcover) |
Availability
| Library | Location | Call Number | Status | Item Actions |
|---|---|---|---|---|
| Electronic Resources | Access Content Online | ✔ Available |