Chromatographic method development / edited by Gregory K. Webster, Laila Kott.
| Other author | Webster, Gregory K. |
| Other author | Kott, Laila. |
| Format | Electronic |
| Publication Info | Singapore : Jenny Stanford Publishing Pte Ltd., [2020] |
| Description | xxiii, 542 pages : illustrations ; 23 cm. |
| Supplemental Content | Full text available from Taylor & Francis eBooks |
| Subjects |
| Series | Jenny Stanford series on pharmaceutical analytics ; volume 3 Jenny Stanford series on pharmaceutical analytics ; v. 3. UNAUTHORIZED |
| Contents | 1. A lesson learned from UHPLC / Gregory K. Webster and Laila Kott -- 2. Software for chromatographic methods development / Aoi Ariyasu and Eiki Maeda -- 3. Flash chromatography method development / J. Robert Bickler -- 4. Orthogonality in chromatographic methods / Zachary S. Breitbach and Gregory K. Webster -- 5. Unified approach to reversed-phase and normal-phase chromatographic method development / Gregory K. Webster -- 6. Polysaccharide-derived chiral stationary phases for the separation of enantiomers / Tong Zhang and Pilar Franco -- 7. Chiral chromatography: method development / Laila Kott and Gregory K. Webster -- 8. Aqueous normal-phase chromatography using Type C silica columns / Joseph J. Pesek and Maria T. Matyska -- 9. Ion chromatography columns / Christopher Pohl -- 10. Ion chromatography: method development / Laila Kott -- 11. Fundamentals, properties, and applications of stationary phases for gas chromatography method development / Omprakash Nacham and Jared L. Anderson -- 12. Gas chromatography method development / Tien Ho and John C. Vinci -- 13. Method transfer between HPLC and UHPLC / Susanne Fabel -- 14. Small-molecule pharmaceutical impurities test method validation: precision acceptance criterion / Russell L. Hertzler, Mark D. Johnson, Teodora Moldovan, Michael D. Oberlander, James Reynolds, Holger van Lishaut, and Yanbing Zehng -- 15. Method development strategies for ion exchange chromatography using pH gradient separation for mAbs, antibody drug conjugates (ADCs) and other complex bio-pharmaceuticals / Norman L. Fischer and Scott Allen -- 16. Size exclusion chromatography method development for therapeutic proteins / Alexandre Goyon, Jean-Luc Veuthey, Davy Guillarme, Szabolcs Fekete -- 17. Countercurrent chromatography using biphasic molecular liquids and ionic liquids: is this the future for laboratory and process purifications? / Leslie Brown and Martyn J. Earle. |
| Abstract | "This book is a comprehensive compilation of modern and cutting-edge chromatographic techniques written by pharmaceutical industry experts, academics and vendors in the field. Edited by Greg Webster and Laila Kott, two industrial pharmaceutical analytical chemists with over 50 years' experience combined. This book is an inclusive guide to developing chromatographic methods for liquid chromatography, gas chromatography, supercritical fluid chromatography, ion chromatography, chiral chromatography, flash chromatography and aqueous normal phase chromatography. This book is valuable to both the novice starting out in undergraduate labs or new to the pharmaceutical industry as well has a helpful reference for more seasoned analysts. This book covers modern techniques for developing methods using chromatographic development software, requirements for validations, discussion on orthoganality and how to transfer methods form HPLC to UHPLC. Finally, this book introduces some newer techniques like ion exchange chromatography and size exclusion chromatography that are heavily employed by chemists analyzing proteins and RNAi as well novel techniques like counter current chromatography."-- Provided by publisher. |
| Bibliography note | Includes bibliographical references and index. |
| Access restriction | Available only to authorized users. |
| Technical details | Mode of access: World Wide Web |
| Genre/form | Electronic books. |
| ISBN | 9789814800532 hardback |
| ISBN | ebook |
| ISBN | 9814800538 hardback |