Freeze drying of pharmaceutical products / edited by Davide Fissore, Roberto Pisano, Antonello Barresi.

Other author Fissore, Davide.
Other author Pisano, Roberto (Of Politecnico di Torino)
Other author Barresi, Antonello.
Format Electronic
Publication InfoBoca Raton : CRC Press, [2020]
Descriptionxvii, 192 pages ; 25 cm.
Supplemental ContentFull text available from Taylor & Francis eBooks
Subjects

SeriesAdvances in drying science and technology
Advances in drying science & technology. ^A1318994
Contents The freeze-drying of pharmaceutical products : Introduction and basic concepts / Davide Fissore, Roberto Pisano, Antonello A. Barresi -- Formulation design and optimization using molecular dynamics / Roberto Pisano, Andrea Arsiccio -- Established and novel excipients for freeze-drying of proteins / Ivonne Seifert, Wolfgang Friess -- Infrared Imaging and Multivariate Image Analysis (MIA): A new PAT for freeze-drying Monitoring and Control / Domenico Colucci, Jos©♭ Manuel Prats-Montalb©Łn, Alberto Ferrer, Davide Fissore -- Through vial impedance spectroscopy (TVIS) : A new method for determining the ice nucleation temperature and the solidification end point / Geoff Smith, Yowwares Jeeraruangrattana -- Innovations in freeze-drying control and in-line optimization / Antonello Barresi, Roberto Pisano, Davide Fissore -- Use of a micro freeze-dryer for developing a freeze-drying process / Taylor N. Thompson, Davide Fissore -- Continuous manufacturing in lyophilization of pharmaceuticals : current status and perspectives / Roberto Pisano, Luigi C. Capozzi, Jos A.W.M. Corver -- Use of CFD for the design and optimization of freeze-dryers / Antonello A. Barresi.
Abstract "Pharmaceuticals typically rely on compounds that are unstable as aqueous solutions and therefore need to be dried for an extended shelf lifetime. While lyophilization remains the gold standard in dehydration technology, it is among the most expensive and time-consuming unit operations in pharma manufacturing. This book provides an overview of the most recent and cutting edge developments and technologies in the field, focusing on formulation developments and process monitoring and considering new technologies for process development like the micro freeze dryer. Case studies from freeze dryer manufacturer and pharmaceutical companies are discussed"-- Provided by publisher.
Bibliography noteIncludes bibliographical references and index.
Access restrictionAvailable only to authorized users.
Technical detailsMode of access: World Wide Web
Genre/formElectronic books.
LCCN 2019026901
ISBN9780367076801 (hardback ; alk. paper)
ISBN(ebook)

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