| Contents |
Schiff base metal complexes : structure and chemical, thermal, optical properties and mechanical structure-property relationships / Divyam Bansal, Shaina Joarder, Madhur Babu Singh, Kamlesh Kumari -- Therapeutic approaches of Schiff base metal complexes in the treatment of diabetes mellitus / Amreeta Preetam, Sangeeta Talwar, Sunny Manohar -- Proliferation inhibition of Schiff base metal complexes / Rajesh Kumar, Komal Aggarwal, Khursheed Ahmad -- Biologically active Schiff base metal complexes as antibacterial and antifungal agent / Prashant Tevatia -- Utilization of Schiff base metal complexes as antiviral and anti-parasitic agent / Shaina Joarder, Divyam Bansal, Madhur Babu Singh, Kamlesh Kumari -- Medicinal activities of anti-inflammatory Schiff base metal complexes / Alka, Pallavi Jain, Seema Gautam -- Role of Schiff base metal complexes in the fight against tumors and cancer / Namita Misra -- Advancement of Schiff base metal complexes interacting with DNA / Mansi, Pankaj Khanna, Leena Khanna -- Schiff base metal complexes in nano-medicines / Anuradha, Jagvir Singh -- Schiff base metal complexes-based sensors for application / Sapna Raghav, Jyoti Raghav -- State of the art and future perspective of Schiff base metal complexes in biological treatment / Archana Gautam, Monica Tyagi -- Molecular docking and drug design of Schiff base metal complexes / Ramadan M. Ramadan, Amani F.H. Noureldeen. |
| Abstract |
"Coordination compounds have been well-known for their wide variety of applications for over a century, as well as enhancing the researcher's interest and concern in evaluating their action mechanism. It is certainly one of the most intensely discussed research topics. Coordination compounds involve different metal-ion-ligand phenomenon. The involved metal ions play a significant role in structural association and functioning of several processes in the genetic and metabolism system. In recent years, Schiff base ligands have gained significant interest and received a keen interest of many researchers. Schiff's base ligands have been recognized to hold a wide variety of biological and medicinal activities due to the presence of donor atoms. They have proved exceptional pharmalogical actions such as antimicrobial, anti-tuberclosis, antiplatelet, antidiabetic, antiarthritis, antioxidant, anti-inflammatory, anticancer, antiviral, antimalarial, and analgesic. These biologically active Schiff base ligands have also been shown to inhibit enzyme mobilization and, when bound to a metal ion, exhibit enhanced biological activity, making them useful in a number of fields. As a result, metal complexes of Schiff base ligands are gaining popularity due to their unique properties and functionalities. Schiff base complex-based research for educational and industrial purposes is booming, and the number of publications is gradually increasing. Despite these interests, there is currently no detailed book on Schiff base metal complexes that covers the structures, biological activities, and other non-biological perspectives. This book delves into the structures of Schiff base metal complexes, which are critical in assessing the biological viability of any complex. It also highlights their biological significance in pharma and drug discovery like antibacterial, antifungal, anticancer, anti-inflammatory, anti-arthritis, anti-diabetic, antioxidants, anti-proliferative, antitumor, anticancer, antiviral. The fundamentals of metal complexes are described, as well as an up-to-date outline of developments in synthesis, characterization methods, properties- chemical, thermal, optical, structural, and applications. This book also discusses the other applications of Schiff base metal complexes: as sensor (luminescent, electrochemical, and biosensor), as pigments in dying and paint industries, as photocatalyst to improve the degradation rate"-- Provided by publisher. |
